Vitamin D levels and Cancer Incidence in 217.244 individuals from Primary Health Care in Denmark
International Journal of Cancer, https://doi.org/10.1002/ijc.32105
Fie Juhl Vojdeman PhD Christian Medom Madsen MD Kirsten Frederiksen PhD Darshana Durup PhD Anja Olsen PhD Louise Hansen PhD …
Wonder why a few cancers show increased rates with higher levels of vitamin D
They excluded those people who already had (some form of) Cancer.
Is this exclusion a clue?
Cancer category starts with the following
- Cancer
295 items Overview Cancer and vitamin D - Cancer and Vitamin D - many studies
- After Cancer Diagnosis
113 items - Bladder Cancer
28 items - Breast Cancer
259 items Overview Breast Cancer and Vitamin D - Colon Cancer
145 items Overview Cancer-Colon and vitamin D - Leukemia
19 items - Liver Cancer
17 items - Lung Cancer
55 items Overview Lung cancer and vitamin D - Lymphoma Cancer
26 items - Other Cancer
66 items - Ovarian Cancer
26 items - Pancreatic Cancer
58 items - Prostate Cancer
103 items Overview Prostate Cancer and Vitamin D - Skin Cancer
121 items Overview Suntan, melanoma and vitamin D - Childhood Cancers - Vitamin D can help - many studies
- Easiest way to treat cancer – take Vitamin D – Nov 2022
- 13 Cancers are helped by Vitamin D – Biobank July 2023
- 2X increase of 14 cancers in non-seniors in 20 years (low vitamin D) – Sept 2022
- Vitamin D prevents and treats cancer in many ways – May 2021
- Those with recent cancer diagnosis had 7X increased risk of COVID-19 (more if A-A )- Dec 2020
- Deaths from many types of Cancer associated with low vitamin D- review of meta-analyses Sept 2020
- Cancer incidence and mortality is decreased if 40-60 ng of Vitamin D – April 2019
- 8 ways that Cancer might be prevented by Vitamin D - June 2019
- Cancer stem cells and Vitamin D - many studies
- Vitamin D Reduces Cancer Risk - Why Scientists Accept It but Physicians Do Not - Feb 2019
- Overview of Vitamin D Actions in Cancer – 31 page chapter in a book – 2018
- Vitamin D prevents breast cancer, reduces BC mortality, and reduces BC chemotherapy problems – Sept 2018
- Diagnosed with breast cancer – take vitamin D to cut chance of death by half – July 2018
- Melanoma 25 X more likely if low vitamin D – Feb 2018
- Better Cancer survival if higher vitamin D a decade earlier (esp. Melanoma, Kidney, Prostate)– Aug 2018
Cancers get less Vitamin D when there is a poor Vitamin D Receptor- Vitamin D Receptor pages in VitaminDWiki with CANCER in title 86 as of July 2023
- Cancer and the Vitamin D Receptor, a primer – Sept 2017
- Vitamin D Receptor (Cancers OR Viruses) - many studies
- Risk of Cancer increased if poor Vitamin D Receptor – meta-analysis of 73 studies Jan 2016
- Cancer (general) and VDR
23 articles - Breast Cancer and VDR
24 articles - Colon Cancer and VDR
13 articles - Prostate Cancer and VDR
7 articles - Skin Cancer and VDR
10 articles - Note some Health problems, such as some Cancers, protect themselves
by actively reducing Receptor activation
Download the Sci-Hub via PDF from VitaminDWiki
The following charts are probably for
Melanoma, Non-melanoma, Prostate, Hematological, Non-Hodgkin, Lymphoma, Lung
(the figures in the submitted PDF was not clearly labeled)
Vitamin D has been linked to cancer development in both pre‐clinical and epidemiological studies. This study examines the association between serum levels of vitamin D and cancer incidence in the Capital Region of Denmark. Individuals who had vitamin D analyzed at The Copenhagen General Practitioners Laboratory between April 2004 and January 2010 were linked to Danish registries with end of follow‐up date at Dec 31st 2014, excluding individuals with pre‐existing cancer. Cox regression models adjusted for age in one‐year intervals, sex, month of sampling, and Charlson Comorbidity Index were applied. The study population of 217,244 individuals had a median vitamin D level of 46 nmol/L (IQR 27‐67 nmol/L).
Non‐melanoma skin cancer was the most frequent form of cancer, followed by breast‐, lung‐, and prostate cancers.
No associations were found between increments of 10nmol/L vitamin D and incidence of breast, colorectal, urinary, ovary or corpus uteri cancer.
However, higher levels of vitamin D were associated with higher incidence of- non‐melanoma (HR 1.09 [1.09‐1.1]) and
- melanoma skin cancer (HR 1.1 [1.08‐1.13]) as well as
- prostate (HR 1.05 [1.03‐1.07]) and
- hematological cancers (HR 1.03 [1.01‐1.06]),
but with lower incidence of
- lung cancer (HR 0.95 [0.93‐0.97]).
In this study, vitamin D levels are not associated with the incidence of several major cancer types, but higher levels are significantly associated with a higher incidence of skin, prostate, and hematological cancers as well as a lower incidence of lung cancer. These results do not support an overall protective effect against cancer by vitamin D.
Rates of some newly diagnosed Cancers increased with higher Vitamin D (217,000 Danes) – Jan 2019(Cached) Printer Friendly Follow this page for updates4418 visitors, last modified 08 Jan, 2019, This page is in the following categories (# of items in each category)Attached files
ID Name Uploaded Size Downloads 11178 Denmark Cancer 7.jpg admin 08 Jan, 2019 29.69 Kb 1044 11177 Denmark Cancer 6.jpg admin 08 Jan, 2019 29.58 Kb 1082 11176 Denmark Cancer 5.jpg admin 08 Jan, 2019 30.21 Kb 1070 11175 Denmark Cancer 4.jpg admin 08 Jan, 2019 27.55 Kb 1013 11174 Denmark Cancer 3.jpg admin 08 Jan, 2019 31.44 Kb 990 11173 Denmark Cancer 2.jpg admin 08 Jan, 2019 37.97 Kb 1031 11172 Denmark Cancer 1.jpg admin 08 Jan, 2019 26.60 Kb 803 11171 Denmark Cancer-min.pdf admin 08 Jan, 2019 357.15 Kb 558 - Breast Cancer and VDR