Chapter 94 - Overview of Vitamin D Actions in Cancer
Vitamin D (Fourth Edition), Volume 2: Health, Disease and Therapeutics, 2018, Pages 711-742
https://doi.org/10.1016/B978-0-12-809963-6.00094-8
Throughout the last 2 or 3 decades it has become evident that vitamin D has effects beyond calcium and bone metabolism. A wide variety of cells and tissues are affected by vitamin D. These targets include tumor cells and the findings have led to a vast series of studies on the actions of vitamin D on cell growth regulation, treatment of cancer and development of potent synthetic vitamin D analogues as inhibitors of cancer cell growth. Various specialized chapters in this book will discuss in detail the effects of vitamin D on specific cancers. In this chapter our goal is to set the stage by providing an overview of the history and current state of knowledge of the field. We will address several areas: recent developments in studies of vitamin D and cancer, regulation of tumor cells, possible mechanisms, and clinical applications.
Cancer category starts with the following
- Cancer
295 items Overview Cancer and vitamin D - Cancer and Vitamin D - many studies
- After Cancer Diagnosis
113 items - Bladder Cancer
28 items - Breast Cancer
259 items Overview Breast Cancer and Vitamin D - Colon Cancer
145 items Overview Cancer-Colon and vitamin D - Leukemia
19 items - Liver Cancer
17 items - Lung Cancer
55 items Overview Lung cancer and vitamin D - Lymphoma Cancer
26 items - Other Cancer
66 items - Ovarian Cancer
26 items - Pancreatic Cancer
58 items - Prostate Cancer
103 items Overview Prostate Cancer and Vitamin D - Skin Cancer
121 items Overview Suntan, melanoma and vitamin D - Childhood Cancers - Vitamin D can help - many studies
- Easiest way to treat cancer – take Vitamin D – Nov 2022
- 13 Cancers are helped by Vitamin D – Biobank July 2023
- 2X increase of 14 cancers in non-seniors in 20 years (low vitamin D) – Sept 2022
- Vitamin D prevents and treats cancer in many ways – May 2021
- Those with recent cancer diagnosis had 7X increased risk of COVID-19 (more if A-A )- Dec 2020
- Deaths from many types of Cancer associated with low vitamin D- review of meta-analyses Sept 2020
- Cancer incidence and mortality is decreased if 40-60 ng of Vitamin D – April 2019
- 8 ways that Cancer might be prevented by Vitamin D - June 2019
- Cancer stem cells and Vitamin D - many studies
- Vitamin D Reduces Cancer Risk - Why Scientists Accept It but Physicians Do Not - Feb 2019
- Overview of Vitamin D Actions in Cancer – 31 page chapter in a book – 2018
- Vitamin D prevents breast cancer, reduces BC mortality, and reduces BC chemotherapy problems – Sept 2018
- Diagnosed with breast cancer – take vitamin D to cut chance of death by half – July 2018
- Melanoma 25 X more likely if low vitamin D – Feb 2018
- Better Cancer survival if higher vitamin D a decade earlier (esp. Melanoma, Kidney, Prostate)– Aug 2018
Cancers get less Vitamin D when there is a poor Vitamin D Receptor- Vitamin D Receptor pages in VitaminDWiki with CANCER in title 86 as of July 2023
- Cancer and the Vitamin D Receptor, a primer – Sept 2017
- Vitamin D Receptor (Cancers OR Viruses) - many studies
- Risk of Cancer increased if poor Vitamin D Receptor – meta-analysis of 73 studies Jan 2016
- Cancer (general) and VDR
23 articles - Breast Cancer and VDR
24 articles - Colon Cancer and VDR
13 articles - Prostate Cancer and VDR
7 articles - Skin Cancer and VDR
10 articles - Note some Health problems, such as some Cancers, protect themselves
by actively reducing Receptor activation
Vitamin D Receptor has the following types of Cancer as of March 2019
Risk Increase Cancer 4.6 Breast Cancer 16.9 X another study 3.1 Colon Cancer survival 2.7 Gastric Cancer 2.4 Lung Cancer 2 Melanoma Non-melanoma Skin Cancers 1.6 Prostate Cancer while black  Download the PDF from Sci-Hub via VitaminDWiki
TABLE 94.1 Vitamin D Receptor in Tumors and Malignant Cell Types
Basal Cell Carcinoma
Breast Carcinoma
Bladder Cancer
Cervical Carcinoma
Colonic Adenocarcinoma
Colorectal Carcinoma
Gall Bladder Carcinoma
Glioblastoma
Kaposi Sarcoma
Lung Carcinoma
Lymphocytic Leukemia
Malignant B-Cell Progenitors
Malignant Melanoma
Medullary Thyroid Carcinoma
Myeloid Leukemia
Multiple Myeloma
Osteogenic Sarcoma
Ovarian Carcinoma
Neuroblastoma
Non-Hodgkin’s Lymphoma
Pancreatic Carcinoma
Parathyroid Adenoma
Pituitary Adenoma
Prostate Carcinoma
Renal cell Carcinoma
Squamous cell Carcinoma
Transitional cell Bladder Carcinoma
Uterine CarcinosarcomaTable of contents
Overview of Vitamin D Actions in Cancer – 31 page chapter in a book – 20186623 visitors, last modified 15 Mar, 2019, This page is in the following categories (# of items in each category)Attached files
ID Name Uploaded Size Downloads 11566 Cancer ToC.jpg admin 15 Mar, 2019 32.53 Kb 683 11565 VDR Cancer.jpg admin 15 Mar, 2019 45.52 Kb 339 11564 Overview Vit D and Cancer.pdf admin 15 Mar, 2019 1.71 Mb 764 - Breast Cancer and VDR