Use of vitamin D and infection in patients with chronic kidney disease.
Rev Bras Enferm. 2018;71(suppl 6):2792-2799. doi: 10.1590/0034-7167-2018-0640.
[Article in English, Portuguese]
Silva ECD1, Taminato M1, Fonseca CDD1, Moraes GM1, Longo MCB1, Grothe CE1, Belasco AGS1, Barbosa DA1. ~ha~ dulce.barbosa at unifesp.br
Study amazingly does not state the size of loading nor maintenance doses
Unsure the time period for infection statistics – 0-6 months, 3-6 months? 5-6 months?
Did all chronic kidney patients get maintenance dose?
Kidney category starts with
Overview Kidney and vitamin D contains the following summary
- FACT: The Kidneys are not the primary way to activate vitamin D; the tissues are
- FACT: When the Kidney has problems, there is less active vitamin D (Calcitriol) for the body
- FACT: When the Kidney has problems, there is increased death due to many factors - many of which are associated with lack of Calcitriol
- FACT: There are many ongoing intervention clinical trials trying to determine how much of what kind of vitamin D is needed to treat the problem
- FACT: One Randomized Controlled Trial has proven that Vitamin D treats CKD
- FACT: 38% of seniors have Chronic Kidney Disease and most are unaware of it CDC statistics 2020
- FACT: Taking extra Vitamin D, in various forms, does not cause health problems - even if poor kidney
- Suggestion: Increase vitamin D getting into body now - and increase co-factors so that the vitamin D can be better used
Sun, UV lamp, Vitamin D supplement - probably > 5,000 IU,
Nanoemulstion vitamin D (inside cheek, topically) gets activated Vitamin D to the cells without the need for healthy kidney, liver, or intestine
Calcitriol - which bypasses the need for the kidney to activate vitamin D
Problems with Calcitriol however: typically only lasts for a few hours, also, possible complications
Update: Pre-cursor of active vitamin D made from plants is better than calcitriol – Sept 2012 - Category Kidney and Vitamin D contains
232 items Download the PDF from VitaminDWiki
Supplement Infection Vitamin D 16 % No D 32 % Blood level Loading Dose Maint. Dose <20 ng/mL 3 months 3 months? 20–19 ng/mL 3 month; 3 months? >30 ng/mL no maintenance dose
3 month or 6 month?
OBJECTIVE:
To evaluate the effectiveness of vitamin D supplementation as protection factor against infection of patients with chronic kidney disease on conservative treatment.METHOD:
Retrospective cohort study carried out between 2013 and 2016 in the Conservative Treatment Outpatient Clinics (Ambulatório de Tratamento Conservador) of the Hypertension and Kidney Hospital (Hospital do Rim e Hipertensão) of the Universidade Federal de São Paulo. Data on sociodemographic factors, comorbidity, infection episodes and use or nonuse of vitamin D supplementation for at least 6 months were collected from medical records. The primary outcomes considered in both groups were: presence or absence of infection anywhere on the body (bloodstream, urinary, respiratory and surgical sites).RESULTS:
A total of 263 patients were included and those who received (n=43) vitamin D had 59% less chance of developing infections (OR=0.41; 95%CI; 0.15-0.99), when compared to those who did not receive.CONCLUSION: Vitamin D supplementation was a protective factor against infections of all causes.
Half as much chronic kidney disease infection if supplement with Vitamin D – 2018Printer Friendly Follow this page for updates3723 visitors, last modified 15 Mar, 2019, This page is in the following categories (# of items in each category)