Covid-19, T cells, and Vitamin D

See VitaminDWiki

• Vitamin D improves T Cell immunity – RCT Feb 2016
• T-cells increased with monthly doses of 140,000 IU vitamin D – April 2014
• Autoimmune diseases and over-active T cells (which are deactivated by vitamin D) – March 2014
• The vitamin D receptor and T cell function – June 2013
• Vitamin D helps T-cell and immune system – overview Aug 2011
• Fight Cancer with more than cut, burn, and poison – Nobel prize for T-Cell – Oct 2018
• Vitamin D associated with reduced T-cell attacks in Multiple Sclerosis – Sept 2012
• Vitamin D-binding protein controls T cell responses to vitamin D in the lab – Sept 2014
• Search for treg OR "t-cell" in VitaminDWiki 1860 items as of July 2020
• COVID-19 and Vitamin D
• Autoimmunity, T Cells and vitamin D: A chemical network analysis – May 2013
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• Adaptive and innate immune system, vitamin D genes, and Rheumatoid Arthritis – June 2019
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VitaminDWiki - Immunity and Virus

COVID and T-Cell Studies from the web

Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19 June 29

• Reported on by : Immunity to COVID-19 is probably higher than tests have shown

COVID-19 progression is potentially driven by T cell immunopathogenesis May 19, 2020

• "Our data further reveal that increased rather than decreased SARS-CoV-2 specific T cell immunity is associated with adverse outcome in COVID-19

Single-Cell Analysis Reveals Macrophage-Driven T Cell Dysfunction in Severe COVID-19 Patients May 26

• "Together, our results suggest that severe SARS-CoV-2 infection causes immune dysregulation by inducing M2 polarization and subsequent T cell exhaustion."

Impaired T cell functions along with elevated activated Tregs at the early stage of asymptomatic SARS-CoV-2 infection

• "Interpretation The T cell activation in the asymptomatic SARS-CoV-2 infection experienced a significant suppression and presented impairment of Th1/Th17 and CD8+ T cell functions"

Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19) peer reviewed May 1
COVID-19 patients can rapidly generate virus-attacking T cells, shows study June 27

• reporting on Phenotype and kinetics of SARS-CoV-2-specific T cells in COVID-19 patients with acute respiratory distress syndrome June 26 FREE PDF

Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases - Jan 26  PDF
Vitamin D deficiency correlates with a reduced number of natural killer cells in intensive care unit (ICU) and non-ICU patients with COVID-19 pneumonia Dec 8  PDF

• Our Bodies’ Best Shot Against Omicron Is an Army of Disgusting Murderers The Atlantic Dec 13, 2021
  • Good description of T cells and vaccines, no mention of Vitamin D
• T Cell Wikipedia
• T helper cell Wikipedia
• Regulatory T cell Wikipedia
• Cells of the Immune System
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• More on T Cells, Antibody Levels, and Our Ignorance July 7, 2020
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COVID-19 treated by Vitamin D - studies, reports, videos

As of March 31, 2024, the VitaminDWiki COVID page had:  trial results,   meta-analyses and reviews,   Mortality studies   see related:   Governments,   HealthProblems,   Hospitals,  Dark Skins,   All 26 COVID risk factors are associated with low Vit D,   Fight COVID-19 with 50K Vit D weekly   Vaccines   Take lots of Vitamin D at first signs of COVID   166 COVID Clinical Trials using Vitamin D (Aug 2023)   Prevent a COVID death: 9 dollars of Vitamin D or 900,000 dollars of vaccine - Aug 2023
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