The prevalence of depressive symptoms in Chinese longevous persons and its correlation with vitamin D status
BMC Geriatrics201818:198, https://doi.org/10.1186/s12877-018-0886-0
Yao Yao†, Shihui Fu†, Hao Zhang, Nan Li, Qiao Zhu, Fu Zhang, Fuxin Luan, Yali Zhao and Yao He †Contributed equally
Tiny subset of table in the PDF
| Characteristics | Depression | No Depression | P |
| Vitamin D deficiency (<20ng) | 48% | 36% | < 0.001 |
| BMI kg/m2, | 17.8 | 18.5 | 0.004 |
| Current alcohol drinker | 8.6% | 11.6% | 0.096 |
| ADL impairments | 72% | 49% | < 0.001 |
| Outdoor activities > 1 h/d, | 53% | 63.0% | 0.001 |
1.5 X more likely to be depressed if < 20 ng of Vitamin D
Pages listed in BOTH the categories Depression and Seniors
- Elderly with low vitamin D were depressed, anxious, or stressed (Saudi Arabia) – March 2024
- Depression in seniors greatly reduced by Vitamin D (50,000 IU weekly) – meta-analysis June 2023
- Frailty 2X less likely in depressed seniors having a good level of vitamin D – Nov 2018
- Centenarians with good vitamin D were 1.5 X less likely to depressed – Aug 2018
- Less depression in seniors taking enough Omega-3 – meta-analysis July 2018
- Senior Depression and Vitamin D – review March 2016
- Mood disorders 11X worse for older adults with low vitamin D – 2006
- Many articles on Senior depression - 35 percent with less than 10 ng – Sept 2010
- Elderly men lacking vitamin D tend to be depressed – Sept 2010
- Depressed people had less than 10 ng of vitamin D – July 2010
- Senior women with less than 20 ng vitamin D were 2X more likely to become depressed May 2010
- Table of outcomes for seniors vs vitamin D level
- Depression category listing has
268 items along with related searches - Vitamin D depression RCT canceled: too many were taking Vitamin D supplements, etc. Feb 2018
- People who get little noon-day sun must supplement with Vitamin D – systematic review June 2017
- Parkinson’s disease 2 times less likely if get 2 hours of daily sun – Nov 2016
13 reasons why many seniors need more vitamin D (both dose and level) - July 2023 has the following
- Senior skin produces 4X less Vitamin D for the same sun intensity
- Seniors have fewer vitamin D receptor genes as they age
Receptors are needed to get Vitamin D in blood actually into the cells - Many other Vitamin D genes decrease with age
- Since many gene activations are not detected by a blood test,
more Vitamin D is often needed, especially by seniors - Seniors are indoors more than when they were younger
not as agile, weaker muscles; frail, no longer enjoy hot temperatures - Seniors wear more clothing outdoors than when younger
Seniors also are told to fear skin cancer & wrinkles - Seniors often take various drugs which end up reducing vitamin D
Some reductions are not detected by a vitamin D test of the blood
statins, chemotherapy, anti-depressants, blood pressure, beta-blockers, etc - Seniors often have one or more diseases that consume vitamin D
osteoporosis, diabetes, Multiple Sclerosis, Cancer, ... - Seniors generally put on weight as they age - and a heavier body requires more vitamin D
- Seniors often (40%) have fatty livers – which do not process vitamin D as well
- Reduced stomach acid means less Magnesium is available to get vitamin D into the cells
- Vitamin D is not as bioavailable in senior intestines
- Seniors with poorly functioning kidneys do not process vitamin D as well
- Glutathione (which increases Vitamin D getting to cells) decreases with age
Seniors category has431 items Additional supplements to reduce depression
- How Omega-3 Fights Depression – LEF July 2016
- Depression treated somewhat by Omega-3 (St. John's Wort better) – RAND org reviews 2015
- Depression greatly reduced by taking 250 mg of Magnesium Chloride daily for 6 weeks– RCT June 2017
Download the PDF from VitaminDWiki
Background
Hypovitaminosis D and depressive syndromes are common conditions in old adults. However, little is known about the relationship between vitamin D and depression in exceptional aged people. The objective of this study is to evaluate the relationship between vitamin D levels and depressive symptoms in Chinese longevous persons.Methods
We used a dataset from a cross-sectional survey of a sample of Chinese longevous people with self-reported age 100 or older, including 175 men and 765 women, was conducted from June 2014 to December 2016 in Hainan Province, China. Data on demographics, lifestyle characteristics and health conditions were collected using a structured questionnaire. Anthropometrics and blood samples were obtained following the standard procedure. Depressive symptoms of the participants were assessed using a shortened version of the Geriatric Depression Scale (GDS-15). Serum vitamin D levels were measured using an automated radioimmunoassay.Results
The prevalence of longevous persons with depressive symptoms among the sample was 32.2% (95% confidence interval: 29.7–34.7%). Serum vitamin D levels were lower in participants with depressive symptoms than in those without (20.8 ± 8.7 vs. 23.7 ± 9.7, ng/mL).
Vitamin D deficiency was an independent risk factor for depression after controlling for the potential covariates (Odds ratio = 1.47, 95% Confidence interval = 1.08–2.00; p = 0.014). A negative relationship between serum vitamin D levels and depressive symptoms was also detected, and the relationship remained significant after adjusting for a wide range of other covariates. The multivariate adjusted odds ratio of depressive symptoms for the lowest versus highest quartiles of vitamin D levels was 1.73 (95% confidence interval: 1.10–2.72), and the adjusted odds ratio with a 5 ng/mL decrement of serum 25OHD levels was 1.10 (95% confidence interval: 1.01–1.19).Conclusions
This study showed an inverse association between vitamin D levels and depressive symptoms among Chinese longevous persons. Depressive symptoms should be screened in longevous persons who had vitamin D deficiency. Further studies on vitamin D supplement and prevention along with treatment of depression are needed among very old population.Centenarians with good vitamin D were 1.5 X less likely to depressed – Aug 2018Printer Friendly Follow this page for updates8694 visitors, last modified 20 Oct, 2018, This page is in the following categories (# of items in each category)