Chronic Periodontitis reduced by Vitamin D (60,000 IU weekly for 8 weeks) – RCT July 2023

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Assessment of Outcome of Oral Supplementation of Vitamin D3 as an Adjunct to Scaling and Root Planing in Chronic Periodontitis Patients with Type II Diabetes Mellitus – A Randomized Controlled Clinical Trial

J. of Pharmacy and Bioallied Sciences 15(Suppl 1):p S346-S349, July 2023. DOI: 10.4103/jpbs.jpbs_543_22
Ramaprabha, G1; Khan, Nubesh S.2; Kunusoth, Ramesh3; Kakati, Indrajit4; Hussain Qadri, Syed Shah5; Seshadri, Pavithra Rangarajan6

Background:
Both diabetes and periodontitis affect millions of people worldwide and Vitamin D insufficiency may create a conducive environment for the progression of diabetes and periodontal disease. The aim of the study was to assess the outcome of oral supplementation of Vitamin D3 in patients with Type 2Diabetes Mellitus with generalized chronic periodontitis, as an adjuvant toscaling and root planing.

Methodology:
A total of 92 patients, including 46 each in non-diabetic and diabetec group. Clinical parameters including Plaque Index (PI), Gingival Bleeding Index (GBI), Probing Pocket Depth (PPD), Clinical Attachment Level (CAL), levels of Vitamin D in serum, and Fasting Blood sugar were assessed at the baseline. SRP was finished for each participant in the trial. Following SRP, the first 25 people in each group got 60,000 IU of oral vitamin D3 granules once a week for eight weeks, while the remaining 21 subjects from each group did not. At the conclusion of the 8th week following interventions, all the indicators were reviewed.

Results:
Following SRP and Vitamin D supplementation there was a measurably critical reduction in every one of the periodontal clinical indicators in both groups. In both groups, there was a statistically significant rise in serum vitamin D levels.

Conclusion:
In addition to SRP, vitamin D supplementation shows promise as a host immunomodulatory drug in the management of periodontitis, particularly in patients with diabetes mellitus.
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VitaminDWiki - 7 Dental Interventions

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VitaminDWiki – Dental category contains:

116 Dental items

Some Dental studies

• Vitamin D cut dental caries in half 80 years ago – meta-analysis 2013 80 years ago
• Caries (tooth decay) and Vitamin D - 23+ studies
• Periodontitis reduced by Vitamin D - many studies
  • Periodontal Disease and Vitamin D - interview and transcript - GRH, Grant July 2023
  • Severe periodontitis is half as likely at 60 ng of vitamin D – Sept 2021
  • Vitamin D may provide the most peridontal benefits of all nutraceuticals – May 2018
• Risk of Oral Surgery reduced by Vitamin D – scoping review Nov 2021
• Some Dental Malocclusions 5X more likely if low vitamin D – June 2021
• Grinding teeth while sleeping (sleep bruxism) 6 X more likely if low vitamin D – Jan 2021
• Early tooth decay 1.9 X more likely if a poor Vitamin D receptor – July 2017
• 7 Intervention AND Dental studies
• 19 items listed in BOTH Dental and Infant or Child
• 7 listed in BOTH Dental and Vitamin D Receptor