Vitamin D as a Neurosteroid Affecting the Developing and Adult Brain
Annual Review of Nutrition, Vol. 34:117-141 - July 2014, DOI: 10.1146/annurev-nutr-071813-105557
Natalie J. Groves,1 John J. McGrath,1,2,3 and Thomas H.J. Burne1,2, t.burne at uq.edu.au
 Download the PDF from Sci-Hub via VitaminDWiki
Vitamin D deficiency is prevalent throughout the world, and growing evidence supports a requirement for optimal vitamin D levels for the healthy developing and adult brain. Vitamin D has important roles in proliferation and differentiation, calcium signaling within the brain, and neurotrophic and neuroprotective actions; it may also alter neurotransmission and synaptic plasticity. Recent experimental studies highlight the impact that vitamin D deficiency has on brain function in health and disease. In addition, results from recent animal studies suggest that vitamin D deficiency during adulthood may exacerbate underlying brain disorders and/or worsen recovery from brain stressors. An increasing number of epidemiological studies indicate that vitamin D deficiency is associated with a wide range of neuropsychiatric disorders and neurodegenerative diseases. Vitamin D supplementation is readily available and affordable, and this review highlights the need for further research.
Sections include
INTRODUCTION
THE ACTIONS OF VITAMIN D WITHIN THE BRAIN
RODENT MODELS OF VITAMIN D DEFICIENCY
LINKS WITH NEUROPSYCHIATRIC AND NEURODEGENERATIVE DISORDERS
FUTURE DIRECTIONS
CONCLUSION
Related Vitamin items
- Cognitive category listing has
383 items along with related searches - Overview Alzheimer's-Cognition and Vitamin D
- Depression category listing has
263 items along with related searches - Overview Schizophrenia and Vitamin D
- Autism category listing has
157 items along with related searches - Parkinson category listing has
114 items along with related searches - Stroke category listing has
129 items along with related searches - Epilepsy 14 items as of May 2019
- Overview MS and vitamin D
Google Scholar had 251 studies citing this study as of Dec 2023
- The Synaptic and Circuit Functions of Vitamin D in Neurodevelopment Disorders Feb 2023 https://doi.org/10.2147/NDT.S407731 FREE PDF
- Maternal vitamin D deficiency and brain functions: a never-ending story - 2023 10.1039/D3FO00166K - FREE PDF
- Vitamin D and the brain: Genomic and non-genomic actions - Sept 2017, https://doi.org/10.1016/j.mce.2017.05.035
- Vitamin D and Neurological Diseases: An Endocrine View - Nov 2017 https://doi.org/10.3390/ijms18112482 FREE PDF
- Vitamin D and the nervous system - May 2019 https://doi.org/10.1080/01616412.2019.1622872
- Can Brain Health Be Supported by Vitamin D-Based Supplements? A Critical Review - Sept 2020 https://doi.org/10.3390/brainsci10090660
- Associations of vitamin D deficiency with MRI markers of brain health in a community sample - Jan 2021 https://doi.org/10.1016/j.clnu.2020.04.027
- Vitamin D and brain health: the need for vitamin D supplementation and sensible sun exposure- Holick Sept 2014 has the following chart
VitaminDWiki pages with BRAIN in title (94 as of Oct 2022)
This list is automatically updated
No results for query.
Short URL = is.gd/VitDBrain
Variety of evidence that Vitamin D helps the brain – July 201423189 visitors, last modified 21 Dec, 2023, This page is in the following categories (# of items in each category)Attached files
ID Name Uploaded Size Downloads 12013 groves2014.pdf admin 26 May, 2019 1.03 Mb 1692 9790 Brain Holick 2014.jpg admin 02 May, 2018 47.82 Kb 6804