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Cataracts and Vitamin D - many studies


12+ VitaminDWiki pages with CATARACTS in title

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Items found: 12

Association between vitamin D level and cataract: A systematic review and meta-analysis - Aug 2024

Graefe's Archive for Clinical and Experimental Ophthalmology
Zhenzhen Jue, Ziming Xu, Vincent L. Yuen, Odessa Dik San Chan & Jason C. Yam

Purpose
The association between serum vitamin D level and cataract remains controversial. This study aims to evaluate the association between vitamin D level and cataract.

Methods
In this study, articles in the PubMed, Web of Science, and EMBASE databases were searched up to 30 August 2023 and 626 articles were screened. Four studies involving a total of 10,928 subjects with cataract and 10,117 control subjects met the inclusion criteria.

Results
Decreased serum vitamin D level was associated with higher incidence of cataract (P = 0.047; MD: -4.87; 95%CI: [-9.67, -0.07]). In the subgroup analysis by sex, a significant association was found between serum vitamin D level and cataract in both male (P = 0.01, MD: -2.15,95%CI: [-3.83, -0.46]) and female (P < 0.01; MD: -6.67,95%CI: [-8.20, -5.14]).
In the subgroup analysis by the types of cataract, significant association was found between serum vitamin D level and nuclear (P < 0.01; MD: -10.48; 95%CI: [-12.72, -8.24]) and posterior subcapsular cataract (P = 0.02; MD: -6.05; 95%CI: [-11.30, -0.80]) but not in cortical cataract (P = 0.14; MD: -6.74; 95%CI: [-15.70, 2.22]).

Conclusion
This meta-analysis revealed potential association between serum vitamin D level and cataract, more significant in female, and the subtypes of nuclear and posterior subcapsular cataract.
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60K monthly reduced the risk of cataracts - clipped from PDF

In a recent randomized controlled trial, participants were randomly assigned to receive regular high-dose
vitamin D supplement (60,000 IU once per month) or placebo, and were followed up for a median duration of approximately 5 years.
The results showed no signifcant diference in cataract surgery rates between the experimental group and the placebo group https://doi.org/10.1016/j.ophtha.2022.09.015. We found that high-level serum Vitamin D reduced the risk of cataract, indicating a potential role of vitamin D supplementation in ophthalmologic practice.
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VitaminDWiki – Vision category contains

Vision problems having many studies on VitaminDWiki

109 items in Vision category
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