Vitamin D and Diseases - many different associations
Low Vitamin D Increased risk of Disease
- Low Vitamin D in blood ==> Disease
- Low Calcitriol ==> Disease (not noticed by blood test)
- Low Vitamin D in cell ==> Disease (not noticed by blood test
Disease lowers 1 or more forms of Vitamin D
Disease ==> low Vitamin D in blood (consumes D or changes gene activation)
Disease ==> low Calcitriol (consumes D or changes gene activation)
Disease ==> low D in cell (changes gene activation)
Related in VitaminDWiki
- 97+ Diseases that may be related via low vitamin D in blood
- Genes that increase the risk of Osteoporosis: Vitamin D Receptor is number one in Asians
- Genes which reduce blood-level vitamin D increase the risk of Alzheimer’s disease
- Genes which regulate active vitamin D worsen with age
- Genes are one of the reasons for low response to vitamin D
- Many cancers protect themselves by deactivating Vitamin D activated genes
- Colon Cancer protects itself by changing the VDR and CYP3A4 genes
- Some diseases reduce vitamin D getting to blood or cells
- Restrict conversion of light into vitamin D in the skin
- Restrict oral absorption in the gut
- Restrict semi-activation in the liver
- Restrict free semi-activated vitamin D from getting to the kidneys
- Restrict full activation in the kidneys
- Restrict semi and fully activation in the cells
- Restrict activated Vitamin D from entering cell mitochondria (VDR)
- Destroy the vitamin D before it gets to the cells
- Some diseases restrict vitamin D without changing genes
- The disease just uses/consumes the vitamin D
- The disease upsets the gut, which reduces bioavailability of oral form
- Genetics has the following chart
