Type 1 Diabetes might be prevented by vitamin D - Dec 2025
Type 1 Diabetes Autoimmunity: To What Extent Vitamin D is Beneficial
Biochem Res Int. 2025 Dec 4:2025:3557065. doi: 10.1155/bri/3557065
Haitham Al-Madhagi 1
Autoimmune disorders, characterized by an overactive immune system attacking healthy tissues, are a significant global health concern. A common thread among these disorders is vitamin D deficiency. While the exact relationship between vitamin D and autoimmunity remains a hot research arena, plenty of reports have suggested a strong association between vitamin D and autoimmune conditions, including systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, and Type 1 diabetes, among others.
Type 1 diabetes, in particular, has been extensively studied in relation to vitamin D. Evidence suggests that vitamin D deficiency may play a role in the development of this autoimmune disease. Beyond its well-known function in bone health, vitamin D acts as a key regulator of both innate and adaptive immune responses. This review sought to explore the complex interplay between vitamin D and the immune system, with a particular focus on its potential role in autoimmunity, especially Type 1 diabetes. Moreover, the coupled therapy and clinical trials that have investigated the use of vitamin D as a therapeutic intervention for autoimmune disorders were also examined, highlighting both successes and limitations.
Related in VitaminDWiki
- Take Vitamin D to prevent prediabetes from progressing into diabetes – American Diabetic Association – 2024
- Type 1 Diabetes (Autoimmune) and Vitamin D, Vitamin D Receptor and Cathelicidin
- Type 1 diabetes trial having problems getting participants – too many taking Vitamin D or Omega-3
- Early Type 1 Diabetes May Shorten Women’s Lives by 18 Years
- Type 1 diabetes patients may be pissing away vitamin D
- 99.7% of people who got Diabetes had been regularly consuming food emulsifiers - May 2024
- T1 Diabetes 3X lower risk if high vitamin D (over 40 ng) – Meta-analysis Nov 2020
- Type 1 Diabetes is prevented and treated by Vitamin D – review of 16 studies – Sept 2019
- Prediabetes 1.5 X more likely to go away if take Vitamin D – meta-analysis July 2020
- Type 1 Diabetes is prevented and treated by Vitamin D – review of 16 studies
- 7X less T1 diabetes for children who had taken 2,000 IU of vitamin D daily - Hipponen 2011
