Type 1 diabetes helped with 50,000 IU of vitamin D every two weeks

Effect of vitamin D on hba1c levels of children and adolescents with diabetes mellitus type 1.

Minerva Pediatr. 2014 Nov 20.

Ordooei M1, Shojaoddiny-Ardekani A, Hoseinipoor SH, Soleimanizad R, Miroliai M, Zare-Zardini H.

AIM:

Studies show the relationship between vitamin D deficiency and glucose metabolism disorders. The aim of this study is evaluation of the effect of vitamin D administration in management of diabetes mellitus type 1.

METHODS:

We evaluated the effect of supplementation with vitamin D on HbA1c levels of children and adolescents with diabetes mellitus type 1. In this before-after study, 70 subjects with diabetes mellitus type 1 were enrolled. Fasting serum 25-hydroxyvitamin D, calcium, phosphate, alkaline phosphatase, glucose and HbA1c were measured at the initiation and after the administration of 50,000 IU of vitamin D3 biweekly for 3 months. The results were then compared using paired t-test. Between 70 patients, Five patients excluded from the study because they did not completed the study and finally, 65 subjects finished the study.

RESULTS:

Finally, 65 patients including 35 children and 30 adolescents were recruited. Forty three (66.1%) subjects had vitamin D deficiency (<30ng/ml). Vitamin D administration leads to decrease of fast blood sugar and HbA1c levels significantly in treated group without effect on calcium and alkaline phosphatase levels. So, No significant alterations occurred in calcium and alkaline phosphatase levels after supplementation with vitamin D.

CONCLUSION:

This study showed that HbA1c may be reduced by administration of vitamin D to children and adolescents with diabetes mellitus type 1 without changing the dose of insulin.

Publisher wants about $100 for the PDF

Vitamin D Council has some details from the PDF behind a $5/month paywall

Iran, NOT a random controlled trial

Approximate averages for boys and girls

See also VitaminDWiki

• Overview Diabetes and vitamin D

• Type 1 diabetes strongly associated with low vitamin D – March 2013

• Type 1 Diabetes probability reduced by 2X if have more than 40 ng of vitamin D – Feb 2013

• Type 1 Diabetes associated with low vitamin D, especially in dark skinned youths – Dec 2012

• T1 Diabetes associated with low vitamin D - Nov 2014

• Prevent half of T1 Diabetes with vitamin D levels of 50 ng – Dec 2012

• Probability of Type I diabetes reduced 29 percent with vitamin D – systematic review July 2012

• 44 percent less Type 1 diabetes if high level of vitamin D – white skinned military – March 2013

• T1 diabetes OR type1 diabetes in title 125 in VitaminDWiki as of July 2017

• Type 1 diabetes starting to decrease in Finland, they started Vitamin D fortification in 2003 – July 2013

• HbA1c levels (Diabetes) reduced by monthly 50,000 IU of vitamin D – Dec 2017

pages listed in BOTH of the categories Diabetes and Infant/Child

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See also web

• INTERVENTION Clinical Trials for Type 1 Diabetes and Vitamin D 101 trials as of Oct 2023