Those raising Vitamin D above 30 ng were 1.4 X less likely to die of Heart Attack (VA 19 years)
The Effects of Vitamin D Supplementation and 25-hydroxyvitamin D Levels on The Risk of MI and Mortality
Prakash Acharya M.D., Tarun Dalia M.D., Sagar Ranka M.D., Prince Sethi M.D., Olurinde A. Oni M.B.B.S., M.P.H.j, Maya S. Safarova M.D., PhD, * Deepak Parashara M.D. *tî, Kamal Gupta M.D. *, Rajat S. Barua M.D., Ph.D rajat.barua@va. gov|J
- Department of Cardiovascular Medicine, University of Kansas Medical Cente City, KS
Objective: Aim of the study was to examine the effects of the vitamin D (Vit-D) treatment and non-treatment on Vit-D-deficient patients without a prior history of myocardial infarction (MI).
Materials and Methods: This is an retrospective, observational, nested case-control study of patients (N=20,025) with low 25-hydroxyvitamin D [(25-OH)D] levels (<20 ng/ml) who received care at the Veterans Health Administration from 1999-2018. Patients were divided into three groups: Group A (untreated, levels <20 ng/ml), Group B (treated, levels 21-29 ng/ml), and Group C (treated, levels >30 ng/ml). The risk of MI and all-cause-mortality were compared utilizing propensity score-weighted cox-proportional hazard models.
Results. Among the cohort of 20,025 patients, the risk of MI was significantly lower in Group C, compared to Group B [hazard ratio (HR) 0.65, 95% CI; 0.49-0.85, P=.002] and Group A (HR 0.73, 95% CI; 0.55-0.96), P=.02). There was no difference in the risk of MI between Group B and Group A (HR 1.14, 95% CI; 0.91-1.42, P=.24]. Compared to Group A, both Group B (HR 0.59, 95% CI; 0.54-0.63, P<.001] and Group C ( HR 0.61 , 95% CI; 0.56-0.67, P<.001] had significantly lower all-cause-mortality. There was no difference in all-cause- mortality between Group B and Group C (HR 0.99, 95% CI; 0.89-1.09, P=.78).
Conclusions. In patients with Vit-D-deficiency and no prior history of MI, treatment to the (25-OH)D level of >20 ng/ml and >30 ng/ml was associated with a significantly lower risk of all-cause-mortality. The lower risk of MI was observed only in individuals maintaining the (25-OH)D levels >30 ng/ml.
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Description of the study at MedPage Today Interview of the lead author Video of study by Dr. Campbell Oct 2021
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Cardiovascular Disease is treated by Vitamin D - many studies
Giving free vitamin D to every Iranian would pay for itself by just reducing CVD – Oct 2021
During the 19 year study period it was thought that rasing vitamin D levels to 30 ng was enough
Suspect that>50 ng would be much betterAll items in category Optimum Vitamin D items
Suspect Magnesium and/or Omega-3 would also reduce cardiovascular deaths even more
articles are in both Cardiovascular and Magnesium categories
articles are in both Cardiovascular and Omega-3 categories
Cardiovascular category
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Items in both categories Cardiovascular and Mortality
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VA found less testing for vitamin D resulted in increased health costs – Jan 2012
Veterans and Vitamin D - many studies
Perhaps 4,000 dollars annual less health care costs if supplement with 5 dollars of Vitamin D
- Chart of VA hospital data of current study compared with German hospital data published in 2017
