Systematic Reviews and Vitamin D - Vitamin D Council

What are systematic reviews and are they useful in vitamin D research April 2014

• In summary, systematic reviews are meant to save doctors, researchers and health professionals time and help them come to the right conclusions and recommendations on various topics.

• Random Controlled Trials are expensive

Comment by VitaminDWiki

Unfortunately most Systematic Reviews and Meta-analysis treat all studies equally - ignoring the dose size, which can range from 400 IU to 40,000 IU.

Since most of the studies have been with very low doses, the average amount of vitamin D dose size studied is about 1,000 IU

Imagine trying to make a meta-analysis of some simple drug, say aspirin, where the studies were conducted with doses ranging from 10 mg to 600 mg of aspirin.

The meta-analysis would probably conclude that apirin is not good for anything, not even headache (based on average dose size of perhaps 30 mg)

See also VitaminDWiki

• Fractures reduced with any amount of vitamin D and some Calcium - Cochraine April 2014 example of a study in which Vitamin D just squeeked thru

• Anti-depression medication about as good as big increase in vitamin D – meta-analysis of flawless data April 2014

  •     Which is a rare meta-analysis which discarded data from low dose vitamin D studies

• Search VitaminDWiki for "systematic review" 966 items as of April 2014

• 2311 Systematic Reviews or Meta-Analyses of Vitamin D in PubMed - Nov 2020

• All items in category Meta-analysis and Vitamin D items

• Proof that Vitamin D Works has the following summary

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