Migraine headaches associated with low vitamin D, 4,000 IU often helps – review

Vitamin D in migraine headache: a comprehensive review on literature

Neurological Sciences, pp 1–19

Zeinab Ghorbani Mansoureh Togha Pegah Rafiee Zeynab Sadat Ahmadi Reyhaneh Rasekh Magham Samane Haghighi Soodeh Razeghi Jahromi Maryam Mahmoudi

* Migraines in youths with low Vitamin D wonderfully treated by Vitamin D – June 2019 * Comparing High-dose vitamin D therapies * Migraine headache 5X less likely if optimal level of vitamin D – Oct 2018 * Migraine headaches cut in half by 4,000 IU of vitamin D – RCT Sept 2018 * Chronic migraine headaches 1.4 X more likely with low vitamin D – July 2018 The items in Headache and Magnesium are listed here: {category} Headache has the following on metals and migraines {include}

📄 Download the PDF from Sci-Hub VitaminDWiki

Introduction

As a primary headache, migraine has been established as the first leading disability cause worldwide in the subjects who aged less than 50 years. A variety of dietary supplements have been introduced for migraine complementary treatment. As an anti-inflammatory and antioxidant agent, vitamin D is one of these agents which has been of interest in recent years. Although higher prevalence of vitamin D deficiency/insufficiency has been highlighted among migraineurs compared to controls, there is not any consensus in prescribing vitamin D in clinical practice. Therefore, in the current review, in addition to observational and case-control studies, we also included clinical trials concerning the effects of vitamin D supplementation on migraine/headache.

Methods

Based on a PubMed/MEDLINE and ScienceDirect database search, this review study includes published articles up to June 2019 concerning the association between migraine/headache and vitamin D status or supplementation.

Results

The percentage of subjects with vitamin D deficiency and insufficiency among migraineurs and headache patients has been reported to vary between 45 and 100%. In a number of studies, vitamin D level was negatively correlated with frequency of headaches. The present findings show that supplementation with this vitamin in a dose of 1000–4000 IU/d could reduce the frequency of attacks in migraineurs.

Conclusion

It seems a high proportion of migraine patients might suffer from vitamin D deficiency/insufficiency. Further, the current evidence shows that in addition to routine drug therapy, vitamin D administration might reduce the frequency of attacks in migraineurs. However, these results have yet to be confirmed.