Immune system and vitamin D, with emphasis on Inflammatory Bowel Disease

The Role of Vitamin D in Immune System and Inflammatory Bowel Disease

Journal of Inflammation Research Volume 2022:15 Pages 3167—3185 https://doi.org/10.2147/JIR.S363840

Wu Z , Liu D, Deng F Zengrong Wu,1,2 Deliang Liu,1,2 Feihong Deng1,2 dfh411@csu.edu.cn

1Department of Gastroenterology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, People’s Republic of China;

2Research Center of Digestive Disease, Central South University, Changsha, Hunan, 410011, People’s Republic of China

PDF Table of Contents

Chart: Immune system and Vitamin D

Chart Intestines, Vitamin D and immune system

Inflammatory bowel disease (IBD) is a nonspecific inflammatory disease that includes ulcerative colitis (UC) and Crohn’s disease (CD). The pathogenesis of IBD is not fully understood but is most reported associated with immune dysregulation, dysbacteriosis, genetic susceptibility, and environmental risk factors. Vitamin D is an essential nutrient for the human body, and it not only regulates bone metabolism but also the immune system, the intestinal microbiota and barrier. Vitamin D insufficiency is common in IBD patients, and the abnormal low levels of vitamin D are highly correlated with disease activity, treatment response, and risk of relapse of IBD. Accumulating evidence supports the protective role of vitamin D in IBD through regulating the adaptive and innate immunity, maintaining the intestinal barrier and balancing the gut microbiota. This report aims to provide a broad overview of the role vitamin D in the immune system, especially in the pathogenesis and treatment of IBD, and its possible role in predicting relapse.

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VitaminDWiki pages with IBD or IBS in title (25 as of May 2022)

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VitaminDWiki pages with CROHN in (35 as ofMay 2022)

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VitaminDWiki - Overview Gut and vitamin D contains

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Along with gut-friendly information

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VitaminDWiki - Gut category contains

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VitaminDWiki - Immunity category contains

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Note: Gut-Friendly Vitamin D is far better for those with gut problems

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Note: A time-release vitamin D would probably be good for gut problems - but do not know of a supplier as of May 2022

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VitaminDWiki pages with Colitis in (15 as of May 2022)

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