Hypothesis: Soy isoflavones synergistically aid vitamin D in building bones

Created May 2013

Vitamin D interactions with soy isoflavones on bone after menopause: a review.

Park CY, Weaver CM.

Department of Nutrition Science, Purdue University, 700 W State St, West Lafayette, IN 47907, USA. cypark@purdue.edu

There might also be BAD Soy= with Glysophate * GMO soybeans have high levels of glyphosate – June 2014 * 20 X more Parkinson's and 100X more Autism with GMO soy in China * Huge increases in health problems – risk factors include Vitamin D, Antibiotics, and Roundup * Note: soy does not increase risk of Breast Cancer in Japan(no GMO), but soy does in the US (GMO) Soy milk was associated with more rickets - probably because it was not fortified with Vitamin D (in the US)- It has been fortified since about 2016 * Vitamin D deficiency rickets due to soybean milk 2004

Vitamin D is known to increase Ca absorption in adults. However, the threshold vitamin D status to benefit Ca absorption is lower than the target vitamin D status for higher bone mineral density and lower fracture risk, pointing to another pathway for vitamin D to benefit bone. One possibility is by affecting osteoblast and osteoclasts directly. Vitamin D-related bone metabolism may also be affected by soy isoflavones, which selectively bind to the estrogen receptor ^6; and may reduce bone loss in postmenopausal women. We discuss a possible synergistic effect of soy isoflavones and vitamin D on bone by affecting osteoblast and osteoclast formation and activity in postmenopausal women.

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PMID: 23201836

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Tags: Bone