Hypertension in US pregnancies: 3% in 1989, 10% in 2024 — why?
Details in Claude AI
Hypertension pregnancy Claude.pdf
and
Ruled out:
- More mothers with darker skin: the change in racial mix explains none of the rise.
- Falling vitamin D: measured 25(OH)D within each group was flat or rising while hypertension surged.
Partly explains it:
- Better recording on birth certificates. ( Broader diagnostic criteria (2013).
- Older mothers.
- Obesity contributes, but rates rose just as fast in normal-weight mothers (+79%) as in all mothers (+73%) from 2016 to 2024.
birth certificates didn’t record BMI until 2016
Open questions:
- The strong birth-cohort effect: women born in 1996–2004 have 2.6 times the risk of those born in 1951–1959.
- Why the US and Canada are rising while Norway and Australia are falling.
- Candidate exposures such as ultra-processed food that haven’t been tested against the trend.
Health consequences of Hypertension while pregant
Hypertension in pregnancy harms the mother and the baby, both around the birth and for decades afterward. Preeclampsia and chronic hypertension carry most of the risk; mild gestational hypertension carries the least.
Mother: during pregnancy and just after birth
- Death: hypertensive disorders are a leading cause of pregnancy-related death in the US. They account for about 7.4% of pregnancy-related deaths, and nearly a third of women who died during their delivery hospitalization had one documented. [[MMWR 2022](https://www.cdc.gov/mmwr/volumes/71/wr/mm7117a1.htm)] [Bruno 2022]
- Heart attack and stroke: these are the severe complications most strongly tied to hypertension in pregnancy. [MMWR 2022]
- Other complications, mainly with preeclampsia: stroke, retinal detachment, organ damage or failure, and eclamptic seizures. [PhillyVoice / USPSTF]
- Placental abruption and organ failure are also on the NCHS list of maternal harms. [NCHS]
- Eclampsia: the rate nearly halved in the US from 1989 to 2020. [Bruno 2022]
- After delivery: blood pressure problems can persist or get worse in the weeks after childbirth, so postpartum monitoring matters. [NBC Palm Springs]
Baby
The fetal and newborn harms on the NCHS list are stillbirth, neonatal death, fetal growth restriction, preterm birth and low birth weight. [NCHS] Hypertension in pregnancy is the leading reason doctors deliver babies early. [Victoria 2025]
Risk depends heavily on the type of hypertension. In one hospital cohort (Karachi, 2019–2021), compared with mothers with normal blood pressure: [Pakistan cohort 2022]
| Subtype | Stillbirth aOR | Preterm birth aOR | Low birth weight aOR |
|---|---|---|---|
| Gestational hypertension | 1.39 (not significant) | 1.54 (not significant) | 0.98 (not significant) |
| Preeclampsia | 2.66 | 5.71 | 5.45 |
| Chronic hypertension | 3.03 | 6.25 | 6.19 |
Absolute risks in US hospitals are likely lower, but the ranking by subtype is typical.
Longer term for the child: a meta-analysis of 61 articles found that children exposed to these disorders before birth had higher odds of autism (aOR 1.35) and ADHD (aOR 1.29). Findings for other neurodevelopmental outcomes were inconsistent. [Maher 2018, JAMA Psychiatry]
Mother: decades later
| Outcome after preeclampsia | Relative risk | Source |
|---|---|---|
| Chronic hypertension | 3.70 (mean 14 years later) | Bellamy 2007 |
| Heart failure | 4.19 | Wu 2017 |
| Coronary/ischaemic heart disease | 2.16–2.50 | Bellamy 2007 Wu 2017 |
| Cardiovascular death | 2.21 | Wu 2017 |
| Stroke | 1.81 | Bellamy 2007 Wu 2017 |
| Venous thromboembolism | 1.79 | Bellamy 2007 |
| All-cause death | 1.49 | Bellamy 2007 |
| Cancer | 0.96 (no increase) | Bellamy 2007 |
Hypertensive disorders of pregnancy are also linked to end-stage kidney disease later in life. [Swedish registry] The American Heart Association now treats a history of these disorders as a "risk-enhancing factor" for lifetime cardiovascular disease, with a 2- to 4-fold higher risk of heart failure. [Cameron 2022]
Why this matters for the trend
With about 1 in 10 US mothers now affected, this rise will feed into more maternal heart failure, chronic hypertension and kidney disease over the next 10–30 years. It will also add to early deliveries now.
Sources:
- [Ford 2022, MMWR]
- [Bruno 2022, Obstet Gynecol]
- [NCHS NVSR 75-4]
- [PhillyVoice, USPSTF screening]
- [NBC Palm Springs]
- [Victoria, Australia 2025]
- [Karachi cohort 2022]
- [Maher 2018, JAMA Psychiatry]
- [Bellamy 2007, BMJ]
- [Wu 2017, preeclampsia and CVD]
- [Swedish registry, kidney disease]
- [Cameron 2022, JAMA Netw Open]
Related in VitaminDWiki
- Comparing Preeclampsia and Gestational Hypertension
- Vitamin D supplementation decreased the risk of preeclampsia by 39% – meta-analysis
- Risk of preeclampsia should drop to nearly zero at 60 ng of Vitamin D
- Preeclampsia reduced by Vitamin D - many studies
- Preeclampsia 2.7 X less likely if 50,000 IU of Vitamin D every 2 weeks – meta-analysis
- Preeclampsia 4X less likely if vitamin D levels increased by 8 ng during pregnancy