Hypertension 5 X more likely if low Vitamin D, A, Calcium and Magnesium

ASSOCIATION OF SERUM VITAMIN D AND KEY CO-NUTRIENTS IN RELATION TO HYPERTENSION: A CROSS-SECTIONAL STUDY BASED ON NHANES DATA

Barainca, Pamela – PHD Dissertation, University of MD

Low levels of Hypertension Risk
Vitamin D 1.0
Vitamin D, Calcium, Magnesium 1.75
Vitamin A,
Vitamin D, Calcium, Magnesium		 5.4
See also VitaminDWiki * Hypertension 1.5X more likely if low level of Magnesium - Oct 2014 * Hypertension reduced by Omega-3, especially if previously untreated – meta-analysis July 2014 * Omega-3 not mentioned in the dissertation * Hypertension 30 percent more likely if low vitamin D – meta-analysis March 2013 * Hypertension associated with low Calcium levels– Oct 2011 * Overview Hypertension and Vitamin D Overview * section in Overview: Omega-3, Magnesium and Coenzyme Q10 may each be better than Vitamin D

Observational studies demonstrate strong associations between deficient serum vitamin D (25(OH)D) levels and cardiovascular disease. To further examine the association between vitamin D and hypertension (HTN), data from the 2003-2006 National Health and Nutrition Examination Survey were analyzed to assess whether the association between vitamin D and HTN varies by sufficiency of key co-nutrients necessary for metabolic vitamin D reactions to occur.

Logistic regression results demonstrate independent effect modification by calcium, magnesium, and vitamin A on the association between vitamin D and HTN. Among non-pregnant adults with adequate renal function, those with low levels of calcium, magnesium, and vitamin D levels had 1.75 times the odds of HTN compared to those with sufficient vitamin D levels (p = <0.0001). Additionally, participants with low levels of calcium, magnesium, vitamin A, and vitamin D had 5.43 times the odds of HTN compared to those with vitamin D sufficiency (p = 0.0103).