Diabetic Retinopathy 27 percent more likely if low vitamin D – meta-analysis

Retinopathy Linked to Vitamin D Deficiency MedPageToday – with CME

• “In a meta-analysis that included 11 publications and involved studies that included about 6,000 individuals, diabetic patients with vitamin D deficiency were 26.7% more likely to have diabetic retinopathy than patients who were not deficient in the so-called sunshine vitamin (OR 1.267 [95% CI 1.168-1.373, P<0.001]), said Anawin Sanguankeo, MD, a resident in medicine at Bassett Medical Center, Cooperstown, N.Y.”

• . . “annual meeting of the American Association of Clinical Endocrinologists”

• “. . .mean difference of -2.25 ng/mL (95% CI: -3.64 to -0.87, P=0.001),”

• . . “vitamin D deficiency was defined as a serum level less than 20 ng/mL; optimal vitamin D level was defined as a serum level greater than 30 ng/mL.”

  📄 Download the Abstract from VitaminDWiki Publisher wants $36 for the PDF http://dx.doi.org/10.1016/j.jcjo.2016.10.004

Meta-analysis published in 2017 - same 27%, probably the same meta-analysis

**Relationship between vitamin D deficiency and diabetic retinopathy: a meta-analysis

Jason Zhang, MD, Sikarin Upala, MD, MS'Correspondence information about the author MD, MS Sikarin UpalaEmail the author MD, MS Sikarin Upala, Anawin Sanguankeo, MD

DOI: http://dx.doi.org/10.1016/j.jcjo.2016.10.004 |

The purpose of this study was to evaluate the evidence for an association between diabetic retinopathy (DR) and vitamin D deficiency.

Design: Meta-analysis.

Methods: We included 14 observational studies with 10 007 participants who had undergone assessment for both DR and vitamin D deficiency. Pooled odds ratios (ORs) and 95% CIs were calculated using a random-effect, Mantel–Haenszel analysis.

Results: There was a statistically significant association between DR and vitamin D deficiency with an overall pooled* OR of 1.27 *(95% CI, 1.17–1.37; P = 0.001; I2 = 80%; Pheterogeneity = 0.01). There was also a statistically significant lower serum vitamin D level in patient subgroups with DR versus control groups, with an overall mean difference of –1.32 ng/mL (95% CI, –2.50 to –0.15; P = 0.001; I2 = 89%; Pheterogeneity = 0.01).

Conclusion: There is a statistically significant association between vitamin D deficiency and DR.* Publisher wants $36 for the PDF *---

See also VitaminDWiki* Diabetic Retinopathy associated with low Vitamin D - many studies ** Overview Diabetes and vitamin D contains the following summary *{include}

• All items in category Diabetes and Vitamin D * items All items in category Vision and Vitamin D items ** The items in both Diabetes and Vision are listed here: __

{category}