Breast Cancer medicine pain reduced with 4300 IU vitamin D – RCT
Highlight from Vitamin D May Help Breast Cancer Survivors Stay on Track Medscape Medical News
2012 Annual Meeting of the American Society of Clinical Oncology®
- aromatase inhibitors
- half of the women have severe musculoskeletal pain from these agents, and 18% to 30% report fatigue, [resulting in] a discontinuation rate of about 10% each year,"
30,000 IU of oral vitamin D3 weekly on starting letrozole therapy achieved significant benefits in terms of fatigue, joint pain, and disability from joint pain.
Using the Simple Descriptive Pain Intensity
- 37% of women receiving vitamin D3
- 51% of those in the placebo group
- adverse quality of life events = 42% vs 72%