Angina dramatically reduced by injections of vitamin D twice a month (300,000 IU)

Vitamin D replacement therapy in patients with cardiac syndrome X

Perfusion January 2015 vol. 30 no. 1 60-63

A Andishmand, Z Ansari, MH Soltani, H Mirshamsi mirshamsih@yahoo.com, S Raafat

Cardiovascular Research Center, Afshar Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

Hamide Mirshamsi Cardiovascular Department Afshar Hospital, Jomhoori Blvd Yazd, 8917945556 Iran.

Aims: The aim of present study was to assess whether vitamin D, with proven beneficial effects on the cardiovascular system, has any effect on angina and exercise-induced ischemia in patients with cardiac syndrome X and low serum vitamin D.

Methods: Patients with cardiac syndrome X and low serum vitamin D3 were studied before and after treatment with an intramuscular injection of vitamin D3 (300,000 units, every other week for 2 months). We determined the angina episode (per day) and several indices of exercise capacity.

Results: At the end of the treatment course (75±6 day),

• a significant increase of serum vitamin D3 occurred and was within the normal range (45±8 ng/ml) and

• the frequency of angina improved significantly (p=0.003).

• Exercise duration and maximal work capacity increased significantly (p<0.001).

• Maximal ST-segment depression (mm) decreased significantly (p=0.001).

• The calculated Duck treadmill score improved significantly (p=0.001).

Conclusions: Our findings show that vitamin D replacement therapy in patients with cardiac syndrome X and vitamin D deficiency dramatically improves symptoms and signs of ischemia.

📄 Download the PDF from VitaminDWiki

It appears that the main benefit of injection is that the doctor get more income and does not have to worry about compliance

secondary reason for using injection - poor digestion

300,000 IU averaged over 14 days could be as well accomplished by other means

Example: 50,000 IU of vitamin D every 2nd day

See also VitaminDWiki

• Overview Cardiovascular and vitamin D

• Search VitaminDWiki for ANGINA 286 items as of Nov 2022

• Review of Vitamin D (including free, frequency, injection, how much.) – Sept 2013

• Vitamin D supplementation protocols: loading, injection, etc – RCT June 2014

• Overview Pain and Vitamin D

  Injection contains

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VitaminDWiki Cardiovascular pages with "Cardiac syndrome X" in title (3 as of Nov 2022)

This list is automatically updated

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See also web

• Effect of Vitamin D on Anginal Episodes in Vitamin D Deficient Patients with Chronic Stable Angina on Medical Management Aug 2016
  • 60,000 IU weekly for 8 weeks ==> 20% reduction in # of episodes
  • 📄 Download the PDF from VitaminDWiki