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Osteopenia in 40 percent of Indian women – May 2018

Prevalence of osteoporosis and osteopenia in an apparently healthy Indian population - a cross-sectional retrospective study

Osteoporosis and Sarcopenia, https://doi.org/10.1016/j.afos.2018.04.002, online 5 May 2018
Neelam Kaushala, , Divya Vohoraa, , , Rajinder K. Jalalib, Sujeet Jhac, ,

VitaminDWiki

From a health checkup by high income Indian women – average age 50
Based on measurement of Bone-Mineral-Density (BMD)
They found strong associations of osteopenia with

  1. Smoking
  2. Alcohol
  3. Little exercise

The study did not look for any association of osteopenia with

  1. Excessive clothing
  2. Low Magnesium
  3. Low Vitamin K

The study did not find an association of Vitamin D and osteopenia


See also VitaminDWiki

Some countries have been increasing Vitamin D taken have found decreased bone problems

Overview Osteoporosis and vitamin D contains the following summary

  • FACT: Bones need Calcium (this has been known for a very long time)
  • FACT: Vitamin D improves Calcium bioavailability (3X ?)
  • FACT: Should not take > 750 mg of Calcium if taking lots of vitamin D (Calcium becomes too bio-available)
  • FACT: Adding vitamin D via Sun, UV, or supplements increased vitamin D in the blood
  • FACT: Vitamin D supplements are very low cost
  • FACT: Many trials, studies. reviews, and meta-analysis agree: adding vitamin D reduces osteoporosis
  • FACT: Toxic level of vitamin D is about 4X higher than the amount needed to reduce osteoporosis
  • FACT: Co-factors help build bones.
  • FACT: Vitamin D Receptor can restrict Vitamin D from getting to many tissues, such as bones
  • It appears that to TREAT Osteoporosis:
  •        Calcium OR vitamin D is ok
  •        Calcium + vitamin D is good
  •        Calcium + vitamin D + other co-factors is great
  •        Low-cost Vitamin D Receptor activators sometimes may be helpful
  • CONCLUSION: To PREVENT many diseases, including Osteoporosis, as well as TREAT Osteoporosis
  • Category Osteoporosis has 188 items
  • Category Bone Health has 267 items

Note: Osteoporosis causes bones to become fragile and prone to fracture
  Osteoarthritis is a disease where damage occurs to the joints at the end of the bones

Osteoporosis category includes the following

Pages in BOTH the categories Osteoporosis and Meta-analysis

 Download the PDF from VitaminDWiki
Image
Note the huge decrease in osteopenia/osteoporosis for those aged 70+
Suspect the decrease is due to

  1. Death due to hip fracture
  2. Less able to get to hospital for health checkup


Image

Objectives
An understanding of bone mineral density (BMD) pattern in a population is crucial for prevention and diagnosis of osteoporosis and management of its complications in later life. This study aimed to screen the bone health status and factors associated with osteoporosis in an apparently healthy Indian population.

Methods
A retrospective review of medical records was done in a tertiary-care hospital for the subjects who had undergone preventive health-check-ups that included BMD measurements at femur-neck, total-femur, and lumbar-spine.

Results
We evaluated 524 subjects (age, 50.0 ± 12.4 years) including 41.2% female and 58.8% male subjects. Osteoporosis was present in 6.9% subjects (female, 11.1%; male, 4.2%) and osteopenia in 34% subjects (female, 40.3%; male, 29.9%). Absolute BMD was higher in male subjects (P < 0.001) compared to female subjects at all bone sites. Prevalence of osteoporosis increased with age in female subjects, but not in male subjects.
Osteoporosis rates in the age-groups of 30–39, 40–49, 50–59, 60–69, and ≥70 years were 3%, 3.4%, 14.3%, 18.6%, and 36.4%, respectively in female subjects while prevalence in male subjects was 0%, 4%, 6.5%, 4.3%, and 5.6%, respectively, at lumbar spine. Height (r = 0.234–0.358), weight (r = 0.305–0.388), body mass index (r = 0.143–0.285) and physical activity (r = 0.136–0.153) were positively; and alkaline phosphatase (r = −0.133 to −0.203) was negatively correlated with BMD (all P < 0.01) at all sites. These parameters retained significant correlation after controlling for age and sex. No correlation of serum 25-hydroxy-vitamin-D and calcium was noted with BMD (P > 0.05) at any site.

Conclusions
Further data on absolute BMD, T scores, and prevalence rates of osteoporosis/osteopenia on multiple bone sites have been presented in this article.

Created by admin. Last Modification: Sunday May 6, 2018 15:27:25 GMT-0000 by admin. (Version 6)

Attached files

ID Name Comment Uploaded Size Downloads
9813 O&O.jpg admin 06 May, 2018 14:53 62.79 Kb 222
9812 OO correlations.jpg admin 06 May, 2018 14:22 57.86 Kb 191
9810 Prevalence of osteoporosis and osteopenia.pdf PDF 2018 admin 06 May, 2018 14:21 355.25 Kb 495
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