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All children with Chronic Kidney Disease had low Vitamin D (Pakistan hospital) Jan 2023


25-Hydroxyvitamin-D deficiency in chronic kidney disease stages III, IV, and V in South Asian population: a retrospective cohort

SAGE Open Med 2023 Jan 19;11:20503121221148613. doi: 10.1177/20503121221148613
Muhammad Raheel Abdul Razzaque 1, Sameer Saleem Tebha 2, Alaa Tukruna 3, Aabiya Arif 4, Lucas Marian Kogut 5, Nasir Ali Afsar 6, Dania Shabbir 7, Zain Ali Zaidi 8

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Objective: Vitamin D deficiency in Chronic Kidney Disease is a known fact, but the data regarding the prevalence and extent of vitamin D deficiency in different stages of Chronic Kidney Disease is scarce. This leads to a delay in addressing this issue. We conducted this study to assess vitamin-D deficiency in different stages of Chronic Kidney Disease to improve the evidence available to Physicians and Nephrologists which can help them better address this common finding in Chronic Kidney Disease.

Methods: This retrospective study from a tertiary care hospital in Karachi, Pakistan, included adult Chronic Kidney Disease patients who had their serum 25 Hydroxy vitamin D levels done. The patients were classified according to stages of Chronic Kidney Disease using Estimated Glomerular Filtration Rate values. Appropriate statistical tests were performed to find a correlation between the severity of vitamin D deficiency in different stages of Chronic Kidney Disease with a statistically significant p value of <0.05 and a 95% confidence interval.

Results: In total, 148 patients were included in the study. All patients had serum 25 Hydroxy vitamin D levels less than 30 ng/ml. The severity of vitamin D deficiency was observed to increase progressively from stage 3A Chronic Kidney Disease through stage 5. Vitamin D levels in Chronic Kidney Disease stage 3 were significantly greater than in Chronic Kidney Disease stages 4 and 5 (p value < 0.001), and stage 5 patients had the lowest vitamin D levels in our study. Similar, statistically significant findings were observed for serum phosphate levels, too, with stage 5 Chronic Kidney Disease patients having a greater serum phosphate concentration than stages 3A and 3B (p value = 0.002, 0.006).

Conclusion: All Chronic Kidney Disease patients in our study either had vitamin D insufficiency or deficiency. In addition, we observed a significant decrease in vitamin D levels from Chronic Kidney Disease stage 3 to stage 5. Greater serum phosphate levels were detected in stage 5 compared to stages 3A and 3B.
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66+ VitaminDWiki pages have CKD or CHRONIC KIDNEY DISEASE in title

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Items found: 69
Title Modified
1 in 10 have Chronic Kidney Disease (but only 5% are aware of it) – review Sept 2019 30 Nov, 2023
Chronic Kidney disease 15 X more likely if Vitamin D deficient (Chinese males) – Sept 2023 16 Sep, 2023
Chronic Kidney Disease needs Vitamin D: how much, what kind - many studies 27 Apr, 2023
Seniors raised Vitamin D levels, more COVID survivors, less CKD (Slovakia) – Feb 2023 25 Feb, 2023
All children with Chronic Kidney Disease had low Vitamin D (Pakistan hospital) Jan 2023 06 Feb, 2023
Hyperparathyroidism resulting from CKD eliminated by 8,000 IU of vitamin D daily for 12 weeks– RCT 2018 13 Dec, 2022
Bone biomarkers increased equally by daily, weekly, or monthly Vitamin D (CKD in children in this case) – Nov 2022 02 Nov, 2022
Calcitriol (active Vitamin D) prevents and treats COVID (with Chronic Kidney Disease in this case) June 2022 05 Jul, 2022
Diabetics 5X more-likely to get CKD if have very low Vitamin D – June 2022 30 Jun, 2022
Vitamin D treatment of Chronic Kidney Disease: monthly better than daily – RCT May 2022 10 Jun, 2022
Chronic Kidney Disease study not aware of appropriate forms of vitamin D – March 2014 10 Jun, 2022
4X more Chronic Kidney disease patients are now using vitamin D – March 2014 10 Jun, 2022
Vitamin K2 MK- 7 not as available if have Chronic Kidney Disease - Nov 2021 11 Nov, 2021
More people with Chronic Kidney Disease are now getting Vitamin D prescriptions (India) – Sept 2021 05 Sep, 2021
Vitamin D testers have different test results if there is chronic kidney disease – Sept 2019 16 Feb, 2021
Chronic Kidney Disease decreases Vitamin D in 4 ways – Nov 2017 07 Jan, 2021
Chronic Kidney Disease (stage 3) slowed by 30 ng of Vitamin D and Calcitriol – Dec 2019 06 Dec, 2019
Half as much chronic kidney disease infection if supplement with Vitamin D – 2018 15 Mar, 2019
Chronic Kidney Disease Patients need Vitamin K – Jan 2019 15 Feb, 2019
Chronic Kidney Disease patients need more than 20 ng of Vitamin D – workshop conclusion Oct 2018 09 Oct, 2018
Hypothesis: Magnesium might prevent and treat Chronic Kidney Disease – April 2018 09 Sep, 2018
Just 2 doses of Vitamin D resulted in many benefits (Chronic Kidney Disease)– Jan 2018 06 Jan, 2018
Chronic Kidney Disease and Vitamin D Analogs – commentary Jan 2013 27 Aug, 2017
Depression in Chronic Kidney Disease is predicted to be 6 times more likely if low vitamin D – Feb 2017 25 Aug, 2017
Hemodialysis patients (CKD) helped by weekly 50,000 IU of vitamin D – Jan 2017 27 Jul, 2017
2.4 times more likely to die if have Chronic Kidney Disease and low vitamin D - Sept 2016 18 Jul, 2017
Chronic Kidney Disease mortality is 60 percent less likely if good vitamin D – meta-analysis July 2017 18 Jul, 2017
50 percent of Chronic Kidney Disease treatments in Germany include vitamin D – Dec 2012 13 Jul, 2017
Chronic Kidney disease in 20 percent of seniors in Taiwan – April 2017 30 Apr, 2017
Standard oral vitamin D is not a good way to supplement if have Chronic Kidney Disease – March 2016 20 Mar, 2017
Chronic Kidney disease not helped much by vitamin D provided you ignore dose size – meta-analysis Sept 2013 01 Feb, 2017
7100 IU (50000 weekly) restored vitamin D levels for those with Chronic Kidney Disease – July 2012 21 Sep, 2016
Chronic Kidney Disease not treated by 1400 IU of vitamin D – Nov 2015 20 Nov, 2015
Magnesium reduced calcitriol (active vitamin D) artery calcification in CKD by 50 percent – Oct 2015 22 Oct, 2015
Time-release form of active vitamin D granted a patent for chronic kidney disease – July 2014 26 Jul, 2015
With CKD should measure the active form of vitamin D – April 2012 26 Jul, 2015
Active vitamin D treats Chronic Kidney Disease by stimulating Klotho production – Dec 2012 26 Jul, 2015
Some form of vitamin D may be the lowest cost treatment for CKD – Spanish Sept 2011 16 Mar, 2015
Vitamin D and chronic kidney disease – July 2014 18 Dec, 2014
HFCS or fructose decreases Calcium and vitamin D if have CKD – Feb 2010 30 Jul, 2014
Chronic Kidney Disease reduced with 3600 IU vitamin D (50000 twice a month)– RCT Aug 2012 11 Jun, 2014
Vitamin D receptor activation and Chronic Kidney Disease – Oct 2011 14 May, 2014
4X more Chronic Kidney disease patients using vitamin D – March 2014 11 Apr, 2014
Chronic Kidney disease patients increased use of vitamin D from 10 to 44 percent – March 2014 11 Apr, 2014
Need at least 80 ng of vitamin D if have chronic kidney disease – May 2012 08 Apr, 2014
Chronic Kidney Disease patients need more vitamin D and phosphate – Jan 2014 09 Feb, 2014
Vascular calcification in chronic kidney disease April 2010 21 Dec, 2013
Most Chronic Kidney Disease patients restored their vitamin D levels with just 1,000 IU – Dec 2013 10 Dec, 2013
2000 IU vitamin D3 was not enough for children with chronic kidney disease – Feb 2013 10 Dec, 2013
Chronic Kidney Disease clinical trials of UV in Germany – April 2013 10 Nov, 2013
Inflammation and Vitamin D in Chronic Kidney Disease – May 2013 02 Nov, 2013
Paricalcitol better than vitamin D2 for Chronic Kidney disease – April 2011 13 Jul, 2013
Standard and artificial vitamin D both help Chronic Kidney Disease – meta-analysis April 2013 24 Apr, 2013
Vitamin D reduced risk of death of Chronic Kidney Disease by 30 percent: Meta-analysis March 2013 11 Mar, 2013
Chronic Kidney disease and low vitamin D in disadvantaged populations Nov 2010 21 Jan, 2013
5700 IU of vitamin D helped half with chronic kidney disease if not having dialysis – July 2012 01 Sep, 2012
Chronic kidney disease associated with higher levels of vitamin K1 – July 2012 29 Jul, 2012
Chronic kidney disease and PTH – Calcium – Phosphate – Vitamin D – April 2011 23 May, 2012
Perhaps Vitamin D3 is better than D2 for Chronic Kidney Disease – May 2012 09 May, 2012
Chronic Kidney disease with low vitamin D causes health problems – April 2012 18 Apr, 2012
Chronic Kidney Disease stage not associated with vitamin D levels – March 2012 25 Mar, 2012
Death rate increased 3X for chronic kidney disease if low vitamin D – Nov 2011 04 Nov, 2011
Vitamin D and Chronic Kidney Disease – Aug 2011 02 Sep, 2011
Chronic Kidney Disease meta-analysis of vitamin D – Jan 2011 11 Aug, 2011
Use of vitamin D in chronic kidney disease patients. – May 2010 07 Aug, 2011
33 percent more likely to die of chronic kidney disease if less than 15 ng vitamin D – Aug 2011 07 Aug, 2011
Chronic Kidney disease and vitamin D deficiency – Jan 2011 08 Jan, 2011
Meta-analysis finds vitamin D helps chronic kidney disease – Sept 2010 06 Oct, 2010
Therapeutic window for vitamin D and chronic kidney disease 25 Apr, 2010

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Attached files

ID Name Comment Uploaded Size Downloads
19174 CKD chart.jpg admin 06 Feb, 2023 17.31 Kb 149
19173 CKD S Asia.pdf admin 06 Feb, 2023 152.53 Kb 115