Calcium and vitamin-D supplementation on bone structural properties in peripubertal female identical twins: a randomised controlled trial.
Osteoporos Int. 2011 Feb;22(2):489-98. Epub 2010 Jun 11.
Greene DA, Naughton GA david.greene at acu.edu.au
Centre of Physical Activity Across the Lifespan, School of Exercise Science, Australian Catholic University, Locked Bag 2002, Strathfield, NSW, 2763, Australia.
A randomised controlled trial was used in assessing the impact of 6 months of daily calcium and vitamin-D supplementation on trabecular and cortical bone acquisition at distal tibial and radial sites using peripheral quantitative computed tomography (pQCT). Daily supplementation was associated with increased bone density and bone strength at the distal tibia and radius.
INTRODUCTION: pQCT has not been used to assess bone responses to calcium and vitamin-D supplementation on peripubertal children. This randomised controlled trial aimed to assess the impact of a 6-month daily calcium and vitamin-D supplementation on trabecular and cortical bone acquisition at distal tibial and radial sites using pQCT.
METHODS: Twenty pairs of peripubertal female identical twins, aged 9 to 13 years, were randomly assigned to receive either 800 mg of calcium and 400 IU of vitamin D3, or a matched placebo. Bone structural properties at the distal tibia and distal radius were acquired at baseline and 6 months.
RESULTS: The calcium-supplemented group showed greater gains in trabecular density, trabecular area and strength strain index at the 4% of distal tibial and radial sites compared with the placebo group (p=0.001). Greater gains in cortical area at the 38% and 66% of tibial sites were also found in twins receiving the calcium supplement (p=0.001).
CONCLUSIONS: Daily supplementation for a period of 6 months was associated with increased trabecular area, trabecular density and strength strain index at the ultra-distal tibia and radius and increased cortical area at tibial mid-shaft. PMID: 20544178
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Note: the abstract does not mention the Magnesium, it was in the full paper
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For building bone in young girls (ages 9 to 13), a study found benefit with a supplement providing, on a daily basis, 800 mg of calcium (from calcium citrate and calcium carbonate), 400 IU of vitamin D3, and 400 mg of magnesium (from magnesium citrate) when taken regularly for six months (Greene, Osteoporosis Int 2011). The supplement (Active Calcium Chewable, USANA Health Sciences, Inc.) was taken as four chewable tablets, two with breakfast and two with dinner.
Comment by VitaminDWiki
It would probably be best to have ALL of the vitamin D co-factors needed for building bones
- All items in category Calcium and vitamin D
- Overview Magnesium - there are MANY different kinds
- CLICK HERE for low-cost co-factors
- All items in category Supplements and Vitamin D
- Overview of Bone Fractures
- Magnesium may be more important to kids’ bone health than calcium – May 2013
Full paper is attached to the bottom of this page400 IU of vitamin D Magnesium and Calcium helped Twin bones – Feb 2011
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