The relationship between balance control and vitamin D in Parkinson's disease-a pilot study.
Mov Disord. 2013 Jul;28(8):1133-7. doi: 10.1002/mds.25405. Epub 2013 Apr 2.
Peterson AL1, Mancini M, Horak FB.
BACKGROUND:
Balance problems and falls are a major source of morbidity and mortality in patients with Parkinson's disease.
Vitamin D supplementation reduces falls and sway in neurologically intact elderly fallers, but effects in Parkinson's disease are not established.
METHODS:
To study this relationship and select outcome measures for a vitamin D intervention study, balance function and vitamin D concentration were quantified in a series of Parkinson's patients in a cross-sectional, observational study. Participants underwent a battery of 5 balance tests.
RESULTS:
Serum vitamin D concentrations were correlated inversely with Parkinson's severity, as measured by the motor Unified Parkinson's Disease Rating Scale. Among the balance measures, vitamin D concentrations were correlated with automatic posture responses to backwards translation, specifically with response strength and stance weight asymmetry.
CONCLUSIONS:
These findings support the hypothesis that vitamin D plays a role in balance among patients with Parkinson's disease and identify specific outcome measures for detecting effects of vitamin D upon balance.
PMID: 23554003
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See also VitaminDWiki
- Parkinson’s Disease relationship to Vitamin D
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- Overview Parkinson's and Vitamin D contains the following summary
- Vitamin D associated with Parkinson’s Disease in 55 studies, more studies needed- March 2022
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117 studies - Parkinson’s Disease and Vitamin D – review of 52 studies – May 2022
- Parkinson patients: 60 % taking Vitamin D – Dec 2019
- Low Vitamin D increases Parkinson's by 3X– July 2010 "only" a 30 year test, need more study
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- 10 clinical trials for PD with vitamin D intervention as of June 2023
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- Associated with PD are: Meta-analyses (
12 ), Cognition ( 24 studies), Multiple Sclerosis ( 18 studies), VIRUS ( 4 studies), Omega-3 ( 3 studies), Vitamin D Receptor ( 11 studies) - Note by the Founder of VitaminDWiki: I have twice recommended lots of Vitamin D to treat PD. Both got much better, but one had his doctor him cut back to just 2,000 IU. All of his recovery got reversed. With lots of vitamin D he could sing and bike, but now he can barely talk or walk
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