Diarrhea and Vitamin D - several studies

9+ VitaminDWiki pages have DIARRHEA in the title
Childhood diarrhea 7X higher risk if less than 20 ng of Vitamin D - meta-analysis – 2024

9+ VitaminDWiki pages have DIARRHEA in the title

This list is automatically updated

Items found: 9

Title		Modified
Diarrhea and Vitamin D - several studies		19 Feb, 2024
IBS diarrhea treated by weekly 50,000 IU of Vitamin D – RCT March 2020		25 Mar, 2020
Rotavirus diarrhea is 6X more likely if vitamin D is less than 20 ng – Aug 2015		28 Feb, 2017
Rotavirus diarrhea (nearly every child gets it) is strongly associated with low vitamin D – Aug 2015		27 Feb, 2017
Diarrhea more common in children having low vitamin D - Nov 2014		29 Dec, 2016
Children low on vitamin D were 2X more likely to have diarrhea and vomiting - June 2013		19 Aug, 2015
Hypothesis: A hospital diarrhea epidemic caused vitamin D deficiency – Oct 2012		06 Dec, 2014
2X more childhood diarrhea or ear infection if less than 20 ng of vitamin D – Jan 2013		13 Feb, 2014
100,000 IU of vitamin D every 90 days was not frequent enough to prevent Diarrhea – Sept 2013		09 Sep, 2013

Childhood diarrhea 7X higher risk if less than 20 ng of Vitamin D - meta-analysis – 2024

The relationship of vitamin D deficiency and childhood diarrhea: a systematic review and meta-analysis
BMC Pediatrics (2024) 24:125 https://doi.org/10.1186/s12887-024-04599-0
Glen Lazarus , I Gusti Ngurah Sanjaya Putra, Michelle Clarissa Junaidi1, Jessica Sylvania Oswarl1 and Hanifah Oswari1

Introduction Vitamin D deficiency may increase the risk of childhood diarrhea. We aim to carry out a review and meta-analysis of the evidence relating vitamin D insufficiency to childhood diarrhea.

Methods We searched PubMed, Ovid, Scopus, and Cochrane Library (from inception to August 2022), then independently reviewed the eligibility, and read full-text reviews for selected articles. Keywords used were 'vitamin D, '25-hydroxyvitamin D, 'vitamin D deficiency', 'diarrhea', 'gastroenteritis', 'children', and 'pediatric' The search was limited to studies only in English and with available full-text. Year limitation was not applied in our search. Unpublished trials, dissertations, preliminary reports, conference abstracts, and repositories were excluded from the study. NewcastleOttawa Scale was used as the risk of bias assessment tool. Meta-analysis using the random-effects model was done.

Results Out of 5,565 articles, 12 articles were included in our systematic review, however only 7 articles were eligible for meta-analysis. Meta-analysis showed a statistically significant association between vitamin D deficiency and diarrhea in children in developing countries (OR = 1.79; 95% CI = 1.15 to 2.80; p=0.01). On the secondary outcome, the association of vitamin D deficiency and duration or recurrences of diarrhea are conflicting.

Conclusions There is an association between vitamin D deficiency and the prevalence of diarrhea. Future studies should evaluate the causal association, the impact of vitamin D deficiency on the severity of diarrhea, and whether vitamin D deficiency treatments affects the prevalence of diarrhea.
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