Dosing Error With Over-the-Counter Vitamin D Supplement: A Risk for Vitamin D Toxicity in Infants.
Clin Pediatr (Phila). 2012 Apr 5.
Rajakumar K, Reis EC, Holick MF.
Instead of 400 IU an infant was given 12,000 IU of vitamin D daily for 20 days
Due to parents giving 1 mil liter as they were used to instead of 1 drop, from the new product
Authors were extremely concerned about infant toxicity
However, no problems at all:
Small excerpt from the paper
The infant was clinically stable with no symptoms and was feeding and acting well.
The infant had no history of irritability, constipation, or abnormal movements. Examination revealed a calm, alert, well-appearing infant (weight 5.6 kg; 3rd-15th World Health Organization percentile) with no focal findings except slightly increased patellar deep tendon reflexes; no clonus was present. Serum calcium (10.5 mg/dL, reference range 8.8-10.8 mg/dL), phosphorus (6.4 mg/dL, reference range 4.5-6.5 mg/dL), electrolyte panel, creatinine, and blood urea nitrogen were normal.
20 days at 12,000 IU per day = 240,000 IU
Blood level was 400 ng/ml, which dropped down naturally to 50ng in 4 months
There continues to be is so much fear from vitamin D toxicity – even with decades of experience around the world with very young humans and other mammals with very high levels of vitamin D
Download the PDF from VitaminDWiki
See also VitaminDWiki
- High-dose Vitamin D safe for children (10,000 IU daily, 600,000 IU bolus) – meta-analysis April 2022
- Infants in Finland who got 2000 IU vitamin D daily grew to normal height – March 2011
- Rare infant vitamin D toxicity – due to errors which resulted in more that 240,000 IU – Jan 2014
- 600,000 IU of vitamin D2 given to infants every 4 months for decades in East Germany
- Lambs get 10X more vitamin D3 in their milk formula than humans = 2,000 IU per pint of milk
- All items in category Infant-Child and Vitamin D
853 items - Overview Toxicity of vitamin D which has the following graph for adults
Many weeks for a really large DAILY dose of vitamin D to become toxic for adults
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