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3 tanning sessions raised vitamin D levels about 4 nanograms for about 4 weeks – July 2016

Sustained Increase of 25-Hydroxyvitamin D Levels in Healthy Young Women during Wintertime after Three Suberythemal UV Irradiations-The MUVY Pilot Study.

PLoS One. 2016 Jul 19;11(7):e0159040. doi: 10.1371/journal.pone.0159040. eCollection 2016.
Biersack MG1, Hajdukiewicz M1, Uebelhack R2, Franke L2, Piazena H3, Klaus P1, Höhne-Zimmer V1, Braun T1, Buttgereit F1, Burmester GR1, Detert J1.
1Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, Germany.
2Department of Psychiatry and Psychotherapy, Charité-Universitätsmedizin Berlin, Germany.
3Medical Photobiology Group, Department of Internal Medicine, Charité-Universitätsmedizin Berlin, Germany.

VitaminDWiki

The peak Vitamin D increase a few days after the 3 tanning sessions
Image

  • The benefit was inversly proportional to the initial level of vitamin D
  • The study dose not indicate the duration of the benefit, but generally it (half-life) is also inversely proportional to the vitamin D level
  • They used broad-band UV source (not narrow band) - similar to that of the sun - so there was a lot of UVA

from PDF

  • . . "a dose regime of 1.0–1.5–1.875 SED for women with skin types II and III and 0.8–1.2–1.5 SED for women with skin type I. . "
  • "After the third and last UVR exposure one participant experienced skin dryness, another skin pain, and three mild redness"
  •   . . "all of the symptoms disappeared within the same evening"

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OBJECTIVES:
Vitamin D (VitD) deficiency is a health problem prevalent not only in the elderly but also in young adults. The primary objective of our observational pilot study "MUVY" (Mood, UVR, Vitamin D in Young women) was to test both the short-term and long-term effects of a series of three suberythemal UV radiation (UVR) exposures on the VitD status and well-being of young healthy women during winter in a repeat measure design.
METHODS:
20 healthy young women (Fitzpatrick skin types I-III, aged 21-25 years) received three full body broad band UVR exposures with an escalating erythemally weighted dose schedule during one week in winter, and completed self-report questionnaires monitoring symptoms of depression (Beck Depression Inventory, BDI) and affective state/well-being (Profile of Mood States, POMS) at baseline and three days after the last UVR exposure. 25-hydroxyvitamin D (25(OH)D) and 1,25-dihydroxyvitamin D (1,25(OH)2D) were measured in serum at baseline, and at study days 8, 36 and 50.
RESULTS:
Mean baseline 25(OH)D level was 54.3 nmol/L (standard deviation (s.d.) = 24.1), with seven women having VitD deficient status. Relevant symptoms of depression, as indicated by low BDI total scores (0-8), were absent. After the three UVR exposures the increment of 25(OH)D was an average of 13.9 nmol/L (95% confidence interval (CI) = 9.4-18.4) and 26.2 pmol/L (95%CI = 7.2-45.1) for 1,25(OH)2D. ?25(OH)D, and corresponding baseline levels were significantly and inversely associated (rho = -0.493, p = 0.027). Only 25(OH)D remained significantly increased above baseline for at least six weeks after the last UVR exposure. A strong inverse correlation of the POMS subscale "Vigor/Activity" and the increment in 1,25(OH)2D was found (rho = -0.739, p<0.001) at day 8.
CONCLUSIONS:
Three suberythemal whole body UVR exposures during one week are a simple and suitable method for improving 25(OH)D levels during winter, for at least six weeks, and especially in young women with VitD deficient status.

TRIAL REGISTRATION:: German Clinical Trials Register (Deutsches Register Kinischer Studien) DRKS00009274.
PMID: 27434043

Attached files

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6892 3 tan F2.jpg admin 21 Jul, 2016 12:28 29.30 Kb 716
6891 3 tan sessions.PDF PDF 2016 admin 21 Jul, 2016 12:27 897.43 Kb 573
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