- Association Between Vitamin D and Influenza: Meta-Analysis and Systematic Review of Randomized Controlled Trials
- VitaminDWiki - Overview Influenza and vitamin D
- VitaminDWiki – Flu contains
- It took 50 years for companies to become aware that one dose size is not approprite for all body weights (Aspirin)
Association Between Vitamin D and Influenza: Meta-Analysis and Systematic Review of Randomized Controlled Trials
Front. Nutr., 07 January 2022 https://doi.org/10.3389/fnut.2021.799709
Zhixin Zhu Xiaoxia Zhu Lanfang Gu Yancen Zhan Liang Chen Xiuyang Li*
Department of Epidemiology and Biostatistics, Center for Clinical Big Data and Statistics, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China
Background: Vitamin D supplementation improves the immune function of human body and can be a convenient way to prevent influenza. However, evidence on the protective effect of vitamin D supplementation on influenza from Randomized Controlled Trials (RCTs) is inconclusive.
Methods: RCTs regarding the association between vitamin D supplementation and influenza were identified by searching PubMed, Cochrane library, Embase and Chinese Biomedical Database (CBM) from inception until present (last updated on 10 November 2021). Studies that reported dosages and durations of vitamin D supplementation and number of influenza infections could be included. Heterogeneity was assessed using Cochran's Q test and I2 statistics, the meta-analysis was conducted by using a random-effects model, the pooled effects were expressed with risk ratio (RR) with 95% confidence interval (95% CI).
Results: 10 trials including 4859 individuals were ultimately eligible after scanning. There was no evidence of a significant heterogeneity among studies (I2 = 27%, P = 0.150). Meta-regression analysis finding indicated that country, latitude, average age, economic level, follow-up period and average daily vitamin D intake did not cause the statistical heterogeneity. The study finding indicates that substitution with vitamin D significantly reduces the risk of influenza infections (RR = 0.78, 95% CI:0.64–0.95). No evidence of publication bias was observed. Omission of any single trial had little impact on the pooled risk estimates.
Conclusions: The meta-analysis produced a corroboration that vitamin D supplement has a preventive effect on influenza. Strategies for preventing influenza can be optimized by vitamin D supplementation.
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VitaminDWiki - Overview Influenza and vitamin D
VitaminDWiki – Flu contains
Vitamin D fights all phases of Influenza
- FACT: Vitamin D PREVENTS Influenza 7X lower risk
- FACT: Vitamin D SUPRESSES Influenza ( Vitamin D Hammer )
- Single dose of 50,000 IU of vitamin D stops Influenza symptoms
- FACT: Vitamin D PREVENTS & SUPRESSES Sepsis which is a rare but deadly consequence of Influenza
- FACT: Vitamin D enhances the activity of vaccines.
- FACT: improves Flu vaccine effectiveness and reduces side effects
- FACT: Vitamin D has virtually no side effects
- but 1 in 300 get people get muscle pain or itching due to lower magnesium levels
- FACT: Vitamin D prevents/suppresses over 120 health problems (left column)
- FACT: Both COVID-19 and Influenza are enveloped viruses
- FACT: Do not take vitamin D if Sarcoidosis, excess Calcium, Chemotherapy
- CONCLUSION To help protect/suppress influenza, take 50,000 IU of Vitamin D once a week
during the flu season if you are an average weight adult
A high dose of vitamin D fights Influenza:
Influenza prevented by 40 ng levels or treated with vitamin D hammer (50,000 IU) – June 2015
It took 50 years for companies to become aware that one dose size is not approprite for all body weights (Aspirin)
Meta-analyses of Vitamin D might not adust response to dose size (and duration) for many more decades