The American Journal of Clinical Nutrition, nqz186, https://doi.org/10.1093/ajcn/nqz186
Editorial Rolf Jorde, Guri Grimnes
There is no doubt about vitamin D's role in the development and maintenance of a healthy skeleton. Based on observational studies, one could also be hopeful that vitamin D could prevent much more than rickets—as a “silver bullet” for many diseases. High intakes of vitamin D, sun exposure, and high serum concentrations of 25-hydroxyvitamin D [25(OH)D; the marker of vitamin D status] are all associated with good health. Conversely, low serum 25(OH)D concentrations are consistently associated with the presence of chronic disease risk factors, including hypertension, and predict future diseases such as cancer, cardiovascular disease, diabetes, and even mortality (1). Furthermore, the receptor for the active form of vitamin D (1,25-dihydroxyvitamin D) is found in practically every tissue in which...
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Note: stating average was 46 nmol.they ignored those who ended up less having less than 75 nmol - assuming non-compliant
Intervention of Vitamin D for Depression
- Major Depressive Disorder RCTs often use Vitamin D: 50,000 IU weekly or single 300,000 IU - Review May 2025
- Depression cost-effectively reduced by 50,000 IU of Vitamin D monthly (Iranian teens) – July 2023
- Infants getting an additional 800 IU of vitamin D for 2 years had 60% fewer psychiatric symptoms at age 7 – RCT May 2023
- Anxiety and Depression decreased in senior prediabetics with weekly 25,000 IU of Vitamin D – RCT Sept 2022
- Depression decreased by Vitamin D (12th study in VitaminDWiki) – RCT Nov 2022
- Overweight needed more EPA (4 grams) to fight depression – RCT Aug 2022
- Smoking depression, etc. reduced by Vitamin D (bi-weekly, 50,000 IU) - RCT Dec 2021
- Omega-3 did not prevent depression (they failed to reduce Omega-6, which blocks Omega-3) – RCT Dec 2021
- Weekly Vitamin D plus daily Magnesium is great (reduced depression in obese women in this case) – July 2021
- Depression in psychiatric youths reduced 28 percent after just 1 month of vitamin D – RCT Feb 2020
- Yet another study confirms Depression is treated by weekly Vitamin D (50,000 IU)– RCT Dec 2019
- Depression decreased after vitamin D (50,000 IU weekly to elderly in the case) – RCT Oct 2019
- Vitamin D - no cure for depression (when you use only 1200 IU) – Aug 2019
- Depression reduced in Diabetics with 3 months of 4,000 IU of vitamin D – RCT July 2019
- Vitamin D treatment of diabetes (50,000 IU every 2 weeks) augmented by probiotic – RCT June 2018
- Women had better sexual desire, orgasm and satisfaction after Vitamin D supplementation – Feb 2018
- Vitamin D depression RCT canceled: too many were taking Vitamin D supplements, etc. Feb 2018
- Depression in adolescent girls reduced somewhat by 50,000 IU weekly for 9 weeks – July 2017
- Perinatal depression decreased 40 percent with just a few weeks of 2,000 IU of vitamin D – RCT Aug 2016
- Just 1500 IU of Vitamin D significantly helps Prozac – RCT March 2013
- Reduced depression with single 300,000 IU injection of vitamin D – RCT June 2013
- 40,000 IU vitamin D weekly reduced depression in many obese subjects – RCT 2008
- 50,000 IU Vitamin D weekly Improves Mood, Lowers Blood Pressure in Type 2 Diabetics – Oct 2013
Meta-analyses of Vitamin D and Depression
- Depression reduced by 8,000 IU of Vitamin D daily – meta-analysis Nov 2024
- Depression 1.6 X more likely if low Vitamin D, taking Vitamin D reduces depression – umbrella of meta-analyses – Jan 2023
- Depression in seniors greatly reduced by Vitamin D (50,000 IU weekly) – meta-analysis June 2023
- Depression reduced if take more than 5,000 IU of vitamin D daily – umbrella meta-analysis – Jan 2023
- Depression reduced if use more than 2,800 IU of vitamin D – meta-analysis Aug 2022
- Depression is treated by 2,000 IU of Vitamin D – 2 meta-analyses July 2022
- Depression treated by 50K IU Vitamin D weekly (but not 1,000 IU daily) – meta-analysis Jan 2021
- Mental disorders fought by Omega-3 etc. - meta-meta-analysis Oct 2019
- Depression less likely if more Vitamin D (12 percent per 10 ng) – meta-analysis July 2019
- Anxiety severity reduced if more than 2 grams of Omega-3 – meta-analysis Sept 2018
- Less depression in seniors taking enough Omega-3 – meta-analysis July 2018
- Unipolar depression treated by Omega-3, Zinc, and probably Vitamin D – meta-analysis Oct 2017
- Depression is associated with low Magnesium – meta-analysis April 2015
- Clinical Trials of vitamin D can have “biological flaws” – Jan 2015
- Slight depression not reduced by adding vitamin D if already had enough (no surprise) – meta-analysis – Nov 2014
- Anti-depression medication about as good as big increase in vitamin D – meta-analysis of flawless data April 2014
- Depression might be reduced by vitamin D – meta-analysis March 2014
- Low vitamin D and depression - Study and meta-analysis, April 2013
- 2X more likely to be depressed if low vitamin D (cohort studies) - Meta-analysis Jan 2013
Depression category listing has 273 items along with related searches
10 most recently added items in Depression category in VitaminDWiki
Vitamin D - no cure for depression (when you use only 1200 IU) – Aug 2019
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10 most recently added items in Depression category in VitaminDWiki
| 6523 visitors, last modified 31 Oct, 2019, |
| ID | Name | Uploaded | Size | Downloads | |
|---|---|---|---|---|---|
| 12894 | 1200 IU depression.pdf | admin 31 Oct, 2019 | 699.94 Kb | 538 | |
| 12562 | Depression 1200 IU.jpg | admin 31 Aug, 2019 | 68.86 Kb | 646 |