- Omega-3 fatty acid supply in pregnancy for risk reduction of preterm and early preterm birth
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45 studies in both categories Omega-3 and Pregnancy - 156+ VitaminDWiki pages have PREEMIE or PRE-TERM in the title
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Omega-3 fatty acid supply in pregnancy for risk reduction of preterm and early preterm birth
Am J Obstet Gynecol MFM. 2024 Feb;6(2):101251. doi: 10.1016/j.ajogmf.2023.101251
Irene Cetin 1, Susan E Carlson 2, Christy Burden 3, Eduardo B da Fonseca 4, Gian Carlo di Renzo 5, Adamos Hadjipanayis 6, William S Harris 7, Kishore R Kumar 8, Sjurdur Frodi Olsen 9, Silke Mader 10, Fionnuala M McAuliffe 11, Beverly Muhlhausler 12, Emily Oken 13, Liona C Poon 14, Lucilla Poston 15, Usha Ramakrishnan 16, Charles C Roehr 17, Charles Savona-Ventura 18, Cornelius M Smuts 19, Alexandros Sotiriadis 20, Kuan-Pin Su 21, Rachel M Tribe 22, Gretchen Vannice 23, Berthold Koletzko 24; Clinical Practice Guideline on behalf of Asia Pacific Health Association (Pediatric-Neonatology Branch), Child Health Foundation (Stiftung Kindergesundheit), European Academy of Paediatrics, European Board & College of Obstetrics and Gynaecology, European Foundation for the Care of Newborn Infants, European Society for Paediatric Research, and International Society for Developmental Origins of Health and DiseaseThis clinical practice guideline on the supply of the omega-3 docosahexaenoic acid and eicosapentaenoic acid in pregnant women for risk reduction of preterm birth and early preterm birth was developed with support from several medical-scientific organizations, and is based on a review of the available strong evidence from randomized clinical trials and a formal consensus process.
We concluded the following.- Women of childbearing age should obtain a supply of at least 250 mg/d of docosahexaenoic+eicosapentaenoic acid from diet or supplements, and
- in pregnancy an additional intake of ≥100 to 200 mg/d of docosahexaenoic acid.
Pregnant women with a low docosahexaenoic acid intake and/or low docosahexaenoic acid blood levels have an increased risk of preterm birth and early preterm birth. Thus, they should receive a supply of approximately 600 to 1000 mg/d of docosahexaenoic+eicosapentaenoic acid, or docosahexaenoic acid alone, given that this dosage showed significant reduction of preterm birth and early preterm birth in randomized controlled trials. This additional supply should preferably begin in the second trimester of pregnancy (not later than approximately 20 weeks' gestation) and continue until approximately 37 weeks' gestation or until childbirth if before 37 weeks' gestation. Identification of women with inadequate omega-3 supply is achievable by a set of standardized questions on intake. Docosahexaenoic acid measurement from blood is another option to identify women with low status, but further standardization of laboratory methods and appropriate cutoff values is needed. Information on how to achieve an appropriate intake of docosahexaenoic acid or docosahexaenoic+eicosapentaenoic acid for women of childbearing age and pregnant women should be provided to women and their partners.
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45 studies in both categories Omega-3 and Pregnancy This list is automatically updated
- Intestinal permeability during pregnancy - maintained by Vitamin D, Omega-3, etc. - March 2025
- Should Omega-3 be mandatory in Pregnancy (yes) – July 2024
- Vitamin D and Omega-3 benefits to pregnancy and infants
- Omega-3 fatty acid in pregnancy reduces risk of preterm and early preterm birth – Feb 2024
- Omega-3 fatty acid in pregnancy reduces risk of preterm and early preterm birth – Feb 2024
- Stillbirth reduced by Vitamin D, Zinc, Omega-3 - several studies
- Preterm birth decreased by Omega-3, etc. - many studies
- Preterm birth reduction by nutrients - Vitamin D is the best, Omega-3 is next best – May 2022
- Omega-3 improves pregnancies – Meta-analysis May 2022
- Omega-3 supplementation reduced preterm birth rate by 4X – RCT July 2020
- Conception 1.5 X more likely if taking any amount of Omega-3 – Feb 2022
- Pre-term birth rate cut in half with 1000 milligrams of Omega-3 (if initially low) – RCT May 2021
- Omega-3 recommended in Australia during pregnancy - April 2021
- Pregnancy recommendations – huge differences in Vitamin D, Mg, iron, Iodine, DHA, etc – April 2021
- Seafood (Omega-3) during pregnancy increased childhood IQ by 8 points – review Dec 2019
- Pregnant women in Australia to take Omega-3 when told of reduction in preterm births – Dec 2019
- Fat-soluble vitamins critical for conception, pregnancy and breast feeding (pigs) – Sept 2019
- Preterm Births reduced by Omega-3, Zinc, and Vitamin D – Aug 2019
- Depression after childbirth 5 X less likely if good Omega-3 index – April 2019
- Infant Problem-Solving Skills Linked to Mother’s DHA Omega-3 Level During Pregnancy – April 2019
- Omega-3 during pregnancy and breastfeeding is recommended – May 2019
- Preterm Births decreased by Omega-3 (analysis of 184 countries) – April 2019
- Preterm Births - promising preventions – anti-oxidants, Vitamin D, Omega-3, Zinc, etc. – Jan 2019
- Preterm birth might be prevented by Vitamin D, Omega-3, etc. (International survey) – Jan 2019
- Omega-3 index of 5 greatly decreases the risk of an early preterm birth – Dec 2018
- Omega-3 added during pregnancy helps in many ways – Cochrane Review of RCTs Nov 2018
- Omega-3 helps conception as well as pregnancy – many studies
- More pregnancies and fewer abortions when Omega-3 was added (cows in this case) July 2018
- PCOS treated by a combination of Vitamin D and Omega-3 – RCT Oct 2018
- Omega-3 – fewer than 5 percent of adult women get the RDA – April 2018
- Omega-3, Vitamin D, Folic acid etc. during pregnancy and subsequent mental illness of child – March 2018
- Supplementation while pregnant and psychotic – 20 percent Omega-3, 6 percent Vitamin D – June 2016
- Importance of Vitamin D and fish rarely mentioned during midwife-led prenatal booking visits – July 2017
- Preterm birth rate of pregnant smokers cut in half if take Omega-3 – RCT May 2017
- Gestational diabetes treated by Vitamin D plus Omega-3 – RCT Feb 2017
- Asthma reduced 31 percent when Omega-3 taken during pregnancy – RCT Dec 2016
- Preterm births strongly related to Vitamin D, Vitamin D Receptor, Iodine, Omega-3, etc
- Typical pregnancy is now 39 weeks – Omega-3 and Vitamin D might restore it to full 40 weeks
- Omega-3 supplementation during pregnancy reduce early preterm births (save 1500 USD per child) – Aug 2016
- Rancid Omega-3 increased the odds of newborn mortality by 13 times (rats) – July 2016
- Preterm birth extended by 2 weeks with Omega-3 – Meta-analysis Nov 2015
- Stillbirth rate typically 1 in 200, perhaps only 1 in 800 with Omega-3
- Omega-3 helps pregnancy in many ways: preterm 26 percent less likely etc – review July 2012
- Pregnancy and infants healthier with Omega-3 supplementation - many studies
- Vitamin D, DHA, Folic, Iodine benefits during pregnancy – July 2012
156+ VitaminDWiki pages have PREEMIE or PRE-TERM in the title
This list is automatically updated
Related to: Omega-3, Vitamin D, VDR, Zinc and Selenium
VitaminDWiki - Stillbirth reduced by Vitamin D, Zinc, Omega-3 - several studies (7+)
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