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Overview Autism and vitamin D

Did you know?
  • Autism has seen huge increases around the world in the past few decades
  • There are many proposed reasons for the increase; including antibiotics, Roundup, genetics, vaccines, viral infections, heavy metals,
  • There are 27+ reasons to associate Autism with low vitamin D
  • Children of women who had higher levels of vitamin D have a lower risk of autism
          (More Autism info below)

Learn how Vitamin D is essential for good health
  Watch a 5 minute video "Does Less Sun Mean more Disease?"
  Browse for other Health Problems and D in left column or here
  see also Supplementing and More in the menu at the top of every page
If you have a disease associated with low Vit D take Vit D
Raising your Vit D levels will substantially prevent other low-Vit D health problems
Proof that Vitamin D Works   Getting Vitamin D into your body

Is 50ng enough?   How to restore levels quickly  VitaminDWiki interview and transcript - Jan 2022
Books and Videos 266   Diseases that may be related via low vitamin D
Reasons for low response to vitamin D   Why are doctors reluctant
Cancer studies include:   Breast 254   Colon 141   Lung 55   Prostate 101   Pancreatic 57   Skin 121
Colds and flu   Dark Skin 464   Diabetes 544   Obesity 436   Pregnancy 901   Seniors 431
COVID-19 treated by Vitamin D - studies, reports, videos
  • FACT: Studies have shown many associations between autism to low Vitamin D
  • FACT: Clinical trial has prevented Autism with Vitamin D during pregnancy
  • FACT: Clinical trial has treated autism in children
  • RECOMMENDATION: Take extra vitamin D when pregnant
    There is a tiny risk in taking vitamin D during pregnancy, but a major risk in not doing so if you already have an autistic child

Table of contents

VitaminDWiki - Autism category contains

Autism category has 157 items

 - see also Overview Autism and vitamin D,  Autoimmune ,   Cognitive,    ADHD
Interesting Autistic studies
Autism associated with low Vitamin D

Autism treated by Vitamin D

Autism reduced by vitamins before and during pregnancy

Autism and Vitamin D Receptor (not enough Vit D gets to the cells)
This list is automatically updated

Autism - other risk factors

6 Autism and Virus/Vaccines

Dr. Cannell on Autism and Vitamin D in VitaminDWiki

7 studies: Autism reduced by Omega-3

Summary of this page by CHAT-GPT-4 Sept 2023

Facts:

  • Many studies have shown associations between autism and low Vitamin D levels.
  • Clinical trials have shown that Vitamin D during pregnancy can prevent Autism.
  • Clinical trials have also treated autism in children with Vitamin D.
  • The recommendation is to take extra vitamin D when pregnant. While there's a small risk in taking vitamin D during pregnancy, the risk of not doing so is significant, especially if you already have an autistic child.

Highlighted Studies and Information:

  • Autism was 20X more likely if acetaminophen (Tylenol) was used from age 12 - 18 months (July 2023).
  • There were over 200 studies suggesting a link between vaccines and autism as of 2023.
  • The US saw an explosion of autism cases, with the cost associated with autism reaching $223 billion/year in 2020.
  • Almost 7% of 8-year-old boys in California had autism in 2020, with males being 3.8X more likely to have autism than females.
  • Autism symptoms, in some cases, disappeared by changing the diet.
  • A 3X increase in autism in boys by age 3 was observed if they had 3 hours of daily screen time before age 1 (potentially due to less vitamin D exposure) as of Feb 2022.
  • Autism may be synergistically treated by Vitamin D and probiotics (July 2022).
  • Autism was 2X to 3X more likely if there was a poor Vitamin D Receptor (June 2020).
  • Vaccinations resulted in increased office visits for children 16 months later (Nov 2020).
  • Dr. Cannell, who is associated with the Vitamin D Council, has written and spoken extensively about the relationship between autism and Vitamin D. He suggests that autism can be treated with Vitamin D levels between 80 – 120 ng.

Could You be a "Little Bit Autistic?": The Nonvisible Part of the Spectrum - May 2024

6 minute video by the author
The Nonvisible Part of the Autism Spectrum : Could You be a "Little Bit Autistic?" (Optimistic Autism Book 1) Amazon $10
includes a substantial free portion of his book

Autism treated by a combination of Vitamin D plus Omega-3 - case report 2020

Omega-3 PUFAs and vitamin D co-supplementation as a safe-effective therapeutic approach for core symptoms of autism spectrum disorder: case report and literature review
Nutritional Neuroscience. An International J. on Nutrition, Diet and Nervous System. Vol 23, 2020 - Issue 10 https://doi.org/10.1080/1028415X.2018.1557385
Marco Infante,Barry Sears,Angela Maria Rizzo,Daniela Mariani Cerati,Massimiliano Caprio,Camillo Ricordi

Introduction: Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized by abnormal development of cognitive, social, and communicative skills. Although ASD aetiology and pathophysiology are still unclear, various nutritional factors have been investigated as potential risk factors for ASD development, including omega-3 polyunsaturated fatty acids (PUFAs) and vitamin D deficiency. In fact, both omega-3 PUFAs and vitamin D are important for brain development and function.

Case report: Herein, we report the case of a 23-year-old young adult male with autism who was referred to our Unit due to a 12-month history of cyclic episodes of restlessness, agitation, irritability, and oppositional and self-injurious behaviors. Laboratory tests documented a markedly altered omega-6/omega-3 balance, along with a vitamin D deficiency, as assessed by serum levels of 25-hydroxyvitamin D. Omega-3 and vitamin D co-supplementation was therefore started, with remarkable improvements in ASD symptoms throughout a 24-month follow-up period. A brief review of the literature for interventional studies evaluating the efficacy of omega-3 or vitamin D supplementation for the treatment of ASD-related symptoms is also provided.

Conclusion: To our knowledge, this is the first case reporting remarkable beneficial effects on ASD symptoms deriving from omega-3 and vitamin D combination therapy. This case report suggests omega-3 and vitamin D co-supplementation as a potential safe-effective therapeutic strategy to treat core symptoms of ASD. However, larger studies are needed to evaluate the real efficacy of such therapeutic approach in a broader sample of ASD patients.
 Download the PDF from VitaminDWiki

Autism 20X more likely if acetaminophen (Tylenol) from age 12 - 18 months - July 2023

200+ studies: Vaccines ==> Autism - 2023

If vaccines don't cause autism, then how do you explain all this evidence? Substack June 2023]

  • "There are large cohorts with a no vaccination policy which have NO autism."
  • Clinical pediatric practice for 35 years gave no vaccines and had ZERO autistic children.

Two of his charts: many more health problems in vaccinated
Image

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See also in VitaminDWiki: Problems after childhood vaccinations - many studies

US Explosion of Autism

updated from http://autisminnb.blogspot.com/2011/01/autism-speaks-cdc-autism-prevalence.html
The chart is adapted from http://autisminnb.blogspot.com/2011/01/autism-speaks-cdc-autism-prevalence.html
Autism cases in U.S. jump to 1 in 45 Nov 2015 - based on 2014 data
In 2014, it was 75 % boys, 25 % girls.
Autism – 1 in 40 children in the US (as of 2016) – Nov 2018
CDC update: 1 in 88 as of 2008 Reported March 2012
This is a 78 % increase in (2003-2008) for ALL children
110% increase for Hispanics and 91% increase for black children (2003-2008) (dark skin strongly points to vitamin D)
CDC PDF of the 2008 study which was finally published in 2012 is attached to the bottom of this page
Prevalence of Autism Spectrum Disorder Among US Children and Adolescents, 2014-2016 JAMA 2018
Leveling out? 1.46% (1 in 68) based on a survey of parents - has the child been diagnosed with Autism
Image
1 child in 68 CDC March 2014
An increase of about 30% from 2008 to 2010, which is also a 120% increase in the decade since 2000/2002

Autism Tsunami - US cost $223 billion/year in 2020

Autism Tsunami: the Impact of Rising Prevalence on the Societal Cost of Autism in the United States - May 2021
Journal of Autism and Developmental Disorders May 2021 https://doi.org/10.1007/s10803-021-05120-7
Mark Blaxill • Toby Rogers • Cynthia Nevison

The cost of ASD in the U.S. is estimated using a forecast model that, for the first time, accounts for the true historical increase in ASD. Model inputs include ASD prevalence, census population projections, six cost categories, ten age brackets, inflation projections, and three future prevalence scenarios.
Future ASD costs increase dramatically: total base-case costs of

  • $223 (175-271) billion/year are estimated in 2020;
  • $589 billion/year in 2030,
  • $1.36 trillion/year in 2040, and
  • $5.54 (4.29-6.78) trillion/year by 2060,

with substantial potential savings through ASD prevention. Rising prevalence, the shift from child to adult-dominated costs, the transfer of costs from parents onto the government, and the soaring total costs raise pressing policy questions and demand an urgent focus on prevention strategies.
- - - - - -
A modern day witch trial substack by Rogers in May 2023

  • "The titans of the autism industry have officially banned any discussion of the prevalence, causes, and costs of autism in order to continue profiting from the mass poisoning of children."
  • "A societal cost of autism model (or really any cost of disease model) is pretty straightforward. One just has to calculate the prevalence of the condition in the population and then estimate the costs across several categories — lost parental wages, lost personal wages (for the person with the condition), educational costs, healthcare costs, supportive services (particularly housing) costs — and then just multiply the number of people afflicted times the average cost per person to come up with a number for the whole society."

Almost 7% of 8-year-old California boys (1 in 15) had Autism in 2020 (males 3.8X that of females)

Newly released autism prevalence estimates show that the iatrogenocide is expanding - Rogers Substack March 2023

Autism: mitochondria, toxins, probably helped by supplements - Mercola Dec 2021

  • "More recent investigations looking at mitochondrial biomarkers and electron transport chain activity suggest mitochondrial abnormalities may be involved in as many as 80% of cases."

 Download the PDF from VitaminDWiki

Autism and Dr. Cannell (who is Autistic) at the Vitamin D Council (closed ~2018)

  1. Both have strong inheritance features – Vitamin D about 60%
  2. Both have gotten substantially worse in last 30 years
  3. Vitamin D is known to be involved in brain development
  4. All autistic children are VitD deficient, but not all children who are deficient are autistic: genes are involved
  5. When giving vitamin D to cure children of rickets “mental dullness” decreases as well
  6. Children with genes which give them too much (Williams Syndrome) have to reverse of autism – too sociable
  7. Mothers having lots of fish (and thus more vitamin D) give birth to kids with less autistic symptoms
  8. Both associated with weak bones
  9. Both worse around the age of weaning
  10. Autism is more common in rich families – more likely to apply sun screen and stay indoors
  11. Autism increases with drugs which lower levels of vitamin D
  12. Seizures are common with Autism - Vitamin D has been shown to reduce seizures
  13. Fewer autistic symptoms (such as sleep problems) during summer: when child gets more vitamin D from the sun
  14. Both worse with latitude
  15. Both vary with Ultraviolet light
  16. Both vary with time of year (more birth of autistics in March in Northern hemisphere)
  17. 2X more urban autism – less UVB in urban environments
  18. Both worse with pollution
  19. Both worse with increased clouds and rain
  20. Both worse with closely spaced pregnancies
  21. Autistics have abnormal immune response – similar to that of vitamin D deficiency
  22. Low levels of vitamin D in mother animals reduces brain function in offspring
  23. Vitamin deficient rat pups have similar brain abnormalities to that of human autistic children
  24. Autistic children get less vitamin D in their blood for the same amount of sun exposure
  25. The 4 males/1 female ratio - Note estrogen increases vitamin D in the brain (testosterone does not)
  26. Both worse in African Americans (A-A 2-3 increased autism rate)
  27. Both worse in Dark-skinned immigrants in Europe
  • Study out of China finds correlation between vitamin D status and autism severity Vitamin D Council Oct 2013
    Serum 25-hydroxyvitamin D levels in Chinese children with autism spectrum disorders. - Oct 2013
  • Autism and Vitamin D - by John Cannell, MD Life Extension Jan 2014
  • Autism Causes, Prevention and Treatment: Vitamin D Deficiency etc. – Book April 2015

    • Image

    • Animal study finds that suggests vitamin D may help prevent and treat autistic symptoms. Vitamin D Council Feb 2016
      ". . . "if you want your children to be free of autism, we recommend both mom and dad supplement with 5,000 IU/day of vitamin D for at least 3 months before conception (this dose will also improve both male and female fertility). Then, the pregnant woman should remain on 5,000 IU/day, and perhaps 10,000 IU/day, which is the No Observed Adverse Effects Level (NOAEL) level for vitamin D intake throughout her pregnancy."
      "After the child is born, he or she should supplement with at least 1,000 IU/25 pounds of body weight per day. When the child reaches 125 pounds, he or she should take 5,000 IU/day. If the child shows any signs or symptoms of autism, the dose should be increased to 2,000 IU/per day/per 25 pounds of body weight."

    Vitamin D Council Autism Infographic April 2016
    Image

    140+ VitaminDWiki pages have AUTISM OR AUTISTIC in the title

    This list is automatically updated

    VitaminDWiki - 7 studies in both categories Autism and Omega-3

    This list is automatically updated


    See also:
    Omega-3 polyunsaturated fatty acids and/or vitamin D in autism spectrum disorders: a systematic review - Aug 2023
    https://doi.org/10.3389/fpsyt.2023.1238973 FREEE PDF

    Autism and Vitamin D from Google Scholar 25,300 items Nov 2023

    • Effects of Vitamin D Supplementation on Children with Autism Spectrum Disorder: A Systematic Review and Meta-analysis - May 2023 doi: 10.9758/cpn.2023.21.2.240 FREE PDF
    • Vitamin D Status in Children with Autism Spectrum Disorders: Determinants and Effects of the Response to Probiotic Supplementation - July 2022 FREE PDF
    • Steroid hormone pathways, vitamin D and autism: a systematic review - Feb 2023 FREE PDF
    • Research Progress on the Role of Vitamin D in Autism Spectrum Disorder - May 2022 FREE PDF
    • Vitamin D receptor gene variants and serum vitamin D in childhood autism spectrum disorder - Aug 2022 FREE PDF
    • Vitamin D: Before, during and After Pregnancy: Effect on Neonates and Children - May 2022 - FREE PDF
      • "...while in infants, the clinical conditions are low birth weight, lower bone mass and possible relationship with the development of such diseases as bronchiolitis, asthma, type 1 diabetes, multiple sclerosis, and autism included as VD non-classical actions."
    • The effect of vitamin D supplementation in the treatment of children with autism spectrum disorder: a systematic review and meta-analysis of randomized controlled trials - Sept 2020 FREE PDF
    • The Role of Vitamin D Supplementation in Children with Autism Spectrum Disorder: A Narrative Review - Dec 2021 FREE PDF
    • Maternal Vitamin D Levels During Pregnancy and Offspring Autism Spectrum Disorder - Dec 2021 - https://doi.org/10.1016/j.biopsych.2021.07.012 1.4X increased risk if < 30 nmol
    • The Relationship between Vitamin D and Autism Spectrum Disorder - Dec 2021   FREE PDF

    Autism and Vitamin D on the web

    Image

    Is it Time to Give Up on a Single Diagnostic Label for Autism? Scientific American May 2018

    +"That was the ruling by the editors of the authoritative Diagnostic and Statistical Manual in 2013, but it remains controversial" +"All autistic individuals share core features, including social and communication difficulties, unusually narrow interests, a strong need for repetition and, often, sensory issues. Yet these core features vary enormously in how they are manifested and in how disabling they are." +"There are huge disparities in many areas, such as language development or IQ, and in the presence or absence of co-occurring medical conditions and disabilities"

    HYPOTHESIS Vaccine ==> increased Autism

    The Clear Legal Basis that Vaccines Cause Autism Green Med Info Sept 2018
    Lengthy abstract of book How to End the Autism Epidemic Amazon published Sept 2018,
       #1 Best Seller in Pediatrics Sept 19, 2018

    • The Vaccine Act has a 3-year statute of limitation, and virtually all Autistic behavior is not detected until after the 3-year limitation
    • The one case in which Autism did start within the 3-year time limit was conceded by the govt (and the evidence was sealed), but the 5,500 other Autism claims were thrown out

    Table Of Contents
    Image

    Clinical Review of Autism and Vitamin D 2012 - excellent

    CLICK HERE if registered (free) for VitaminDWiki

    Roundup and Autism

    Powerful chart of the increase in Autism and increase in GMO food
    from http://www.examiner.com/article/data-show-correlations-between-increase-neurological-diseases-and-gmos
    Image

    Roundup May Be Most Important Factor in Development of Autism . . Mercola June 2013
    Dr. Seneff publications many on interactions of roundup on Autism
    Seneff Nov 2014 Winston Price Conference
    Image

    See also VitaminDWiki

    Which has many charts of increases in diseases with Glyphosate - which are HIGHLY LIKELY
    Image

    Perhaps many Females are autistic - but they have very different symptoms than males.

    • Why It’s So Difficult to Diagnose Autism in Girls Slate Oct 2015
      "Some researchers theorize that girls are better than boys at camouflaging their symptoms, particularly during highly structured interactions such as clinic visits. For instance, a colleague of mine described girls with autism as “caricatures” in social interactions. These girls may be motivated to interact, but their behaviors seem exaggerated."
    • The Invisible Women With Autism Atlantic Mag Oct 2015
      Similar article to Slate - very interesting
      Wonder if the perceived ratio of male/female will decrease in the future
    • Vitamin D and Autism Spectrum Disorder: A Literature Review - 2016, 35 pages
       Download the PDF from VitaminDWiki

    Autism appears to be somewhat treated by Omega-3; I wonder if it might prevent it as well

    Items in both categories Autism and Omega-3 are listed here:

    Half of Autistic children have sleep problems such as insomnia

    Autism and Sleep - What Parents Need to Know - Nov 2019

    • 65% have shorter REM sleep, and many autistic children have sleep apnea
    • Bright light in the morning seems to help - similar to helping people with Seaonal Affective Disorder

    It appears that Autistics supplemented with Vitamin D sleep better
    Items in both categories, Autism and Sleep, are listed here:

    Many autism symptoms disappear by changing the food

    sulforaphane
    Fever Benefits for Autism in a Food Video and Transcript -Dr. Greger March 2021
    Nobel Prize for Medicine for brain ailments went to the “father of fever therapy,”
    When the brain gets too hot, it generates heat shock proteins to protect itself
    sulforaphane, the active ingredient in cruciferous vegetables such as broccoli, kale, and collard greens, activates the heat shock response.
    His 2nd video on Autism and Food points out that four different aspects of Autism are treated by sulforaphane

    • shock proteins are released to boost synaptic transmission,
    • Nrf2 is activated to wipe out the free radicals,
    • mitochondrial function is restored,
    • suppress the inflammation triggered by NF-kappa-beta

    Broccoli Compound Eases Autism Symptoms by Mimicking a Child's Fever HealthLine, 2014?
    "During the 18-week study, between 35 and 60 percent of those taking sulforaphane showed decreases in characteristic autism symptoms like repetitive movements, irritability, hyperactivity, and communication problems. "

    A Randomized Controlled Dietary Trial for Autism June 2021, Dr. Greger
    All had symptoms reduced after a gluten- and casein-free diet for a year

    3X increase in Autism in boys by age 3 if 3 hours of daily screen time before age 1 (less vitamin D) - Feb 2022

    Screen time in first year may raise autism risk at age 3 MDEdge   FREE PDF

    16p11.2 deletion syndrome: gene defect associated with Multiple Sclerosis and low vitamin D - June 2022

    Pesticides may increase the risk of Autism - Oct 2021

    Autism Spectrum Disorder and Prenatal or Early Life Exposure to Pesticides: A Short Review - Oct 2021 https://doi.org/10.3390/ijerph182010991 FREE PDF

    • "Conclusions: Among the different environmental pollutants, pesticides should be considered as emerging risk factors for ASD."

    See also: Pesticides 8 X less likely to result in female infertility if take vitamin D – Sept 2023

    3+ Virus pages have AUTISM OR AUTISTIC in the title

    This list is automatically updated

    Autism is associated with other categories: Pregnancy 30, Infant-Child 19, ADHD 15, Intervention 11, Cognitive 10, Omega-3 7, Virus 6, Depression 6, Vitamin D Receptor 5, etc.

    Books, videos on Vitamin D 4, Antibiotics, probiotics 4, Skin - Dark 4 ,Youth 4, Sleep 4; as of May 2024

    Short url = http://is.gd/DAutism

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    20343 Autism case report 2020_CompressPdf.pdf admin 09 Nov, 2023 222.94 Kb 95
    19830 Autism and acetaminophen.pdf admin 21 Jul, 2023 267.35 Kb 139
    19668 Vacc -more problems.jpg admin 17 Jun, 2023 26.71 Kb 619
    19667 Vacc vs unvacc.jpg admin 17 Jun, 2023 33.79 Kb 756
    17745 Sabrina NYT_CompressPdf.pdf admin 05 Jun, 2022 3.71 Mb 332
    16784 Autism Mercola Dec 22, 2021.pdf admin 23 Dec, 2021 275.01 Kb 552
    15784 RCT diet autism 2002.pdf admin 22 Jun, 2021 732.09 Kb 575
    10566 Vaccine autism ToC.jpg admin 19 Sep, 2018 36.22 Kb 7103
    9107 Autism JAMA Jan 2018.jpg admin 03 Jan, 2018 283.67 Kb 10478
    8718 Autsim Omega-3 2017.pdf admin 11 Nov, 2017 623.69 Kb 1488
    6949 Vitamin D and Autism Spectrum Disorder 2016.pdf admin 07 Aug, 2016 370.82 Kb 2065
    6602 Austim VDC April 2016.jpg admin 27 Apr, 2016 138.50 Kb 26615
    4855 Seneff Nov 2014.jpg admin 08 Jan, 2015 114.98 Kb 22347
    4819 Glyphosate and Autism.jpg admin 04 Jan, 2015 45.68 Kb 2164
    4818 Autism prevalence.jpg admin 04 Jan, 2015 68.62 Kb 23765
    4756 Autism book.jpg admin 23 Dec, 2014 47.27 Kb 20992
    4304 Autism - lack of pruning.pdf admin 21 Aug, 2014 3.05 Mb 2197
    4303 Lack of pruning of splines with autism.jpg admin 21 Aug, 2014 19.48 Kb 18496
    4171 Genetic aspect of Autism - 200 to 400 genes.jpg admin 23 Jul, 2014 80.74 Kb 24973
    2623 Autism and air polution.jpg admin 23 Jun, 2013 46.34 Kb 21477
    2622 Autism and air polution.pdf admin 23 Jun, 2013 705.64 Kb 2364
    2438 Autism Spectracell.jpg admin 01 May, 2013 109.30 Kb 35062
    2327 Autism-infographic.png admin 09 Apr, 2013 806.96 Kb 14380
    1270 CDC Autism 2012- reporting on 2008.pdf admin 25 Apr, 2012 637.09 Kb 3524
    1249 Autism Denmark.jpg admin 17 Apr, 2012 12.23 Kb 28267
    1248 ASD CDC 2008.jpg admin 17 Apr, 2012 29.52 Kb 25659
    518 Autism increase with time.jpg admin 30 Mar, 2011 106.10 Kb 12471
    117 season and autism.gif admin 16 Jul, 2010 15.42 Kb 12016
    116 Marc.gif admin 16 Jul, 2010 16.40 Kb 14698