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Falls and Fractures

Falls and Fractures summary

Falls

Fracture

77+ Hip fracture studies in VitaminDWiki title

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Items found: 48
Title Modified
Less than 3 percent of hip fracture patients prescribed enough Vitamin D to make a difference (Malta in this case) – July 2021 26 Jul, 2021
Recommends vitamin D after hip fracture ( but not enough and no-bone building co-factors) – May 2021 21 May, 2021
A call to action: Vitamin D for hip fracture (50,000 weekly for 8 weeks, then bi-weekly – Holick July 2020 11 Dec, 2020
Risk factors for death after hip fracture surgery – 7 of the 8 are associated with low vitamin D – Aug 2020 09 Aug, 2020
Guideline following hip fracture – 50000 IU vitamin D daily for 7 days – Jan 2013 07 Jun, 2020
3.5 X higher risk of death 2 years after hip fracture surgery if low vitamin D – Jan 2020 07 Mar, 2020
Hip surgery with multiple doses of 50,000 IU of vitamin D weekly both before and after – RCT 2023 16 Jan, 2020
Hip fracture rate increases in winter (subtropical Australia too) – Aug 2019 10 Aug, 2019
Warning - High intake of Vitamin B12 and B6 found to increase risk of hip fracture by 47 percent - 2019 19 May, 2019
Following hip fracture 2,000 IU of vitamin D daily improved quality of life – Feb 2019 23 Mar, 2019
Hip fracture recovery best with home exercise plus Vitamin D – RCT Dec 2018 12 Dec, 2018
Death of older hip fracture patients at least 1.6X more likely if low vitamin D – May 2018 19 Nov, 2018
After hip surgery Vitamin D levels dropped by 32 percent – Sept 2018 26 Sep, 2018
Hip fracture 58 percent more likely if low vitamin D – meta-analysis March 2017 20 Dec, 2017
Hip fracture risk reduced 6 percent for each daily dairy serving (more if full-fat dairy) – Oct 2017 28 Oct, 2017
Vitamin D and exercise after hip fracture surgery – far fewer deaths – July 2016 23 Aug, 2017
Most Hip fracture patients had low vitamin D and protein (needed for strong bones) – May 2017 18 May, 2017
1 in 3 died after hip fracture but only 1 in 14 if add Vitamin D and exercise – RCT April 2017 19 Apr, 2017
Vitamin D loading dose after hip fracture surgery was great – RCT Aug 2016 06 Apr, 2017
Following a stroke, a hip fracture is 6X more likely if low vitamin D – July 2001 04 Mar, 2017
Gene makes Hip Fracture 2.5X more likely unless get more vitamin D - Aug 2015 12 Nov, 2016
Partial (proximal) hip fracture strongly associated with low Vitamin D – Aug 2016 08 Nov, 2016
Hip Fracture 2.5 times more likely if poor Vitamin D Binding Protein gene - Aug 2015 25 Sep, 2016
Hip fracture risk increased 2.5X if problem with Vitamin D Receptor gene (GC) – March 2014 25 Sep, 2016
Hip fracture 50 percent more likely if low in both vitamin D and vitamin K1 – Dec 2015 26 Dec, 2015
Hip fracture 3X more likely if low vitamin D – Dec 2015 26 Dec, 2015
7 X more likely to get hip fracture if have highest level of vitamin A – Jan 2003 31 May, 2015
Delirium 2.7 X more likely after hip fracture and low vitamin D – May 2015 27 May, 2015
Hip fracture outcome 5X more likely to be poor if low vitamin D – Jan 2015 16 Mar, 2015
Hip fracture rate varies with latitude (and thus vitamin D) in Sweden – Nov 2013 20 Feb, 2015
Hip Fracture – 5X more likely to have bad outcome if have less than 20 ng of vitamin D – Dec 2014 22 Jan, 2015
Hip fracture – not getting enough vitamin D – 2013 28 May, 2014
Men with hip fracture were 1.6X more likely to have low vitamin D – Aug 2013 09 Nov, 2013
5X increase in hip fracture rates in 65 years - 1998 27 Aug, 2013
Hip fracture reduced 38 percent with Calcium and just 400 IU of vitamin D – RCT Feb 2013 17 Aug, 2013
Male Hip fracture 1.65X more likely if low vitamin D – May 2013 01 Jun, 2013
Vitamin D needed to prevent and treat hip fracture, but only 20 percent got any – May 2013 31 May, 2013
Having less than 25 ng of vitamin D was associated with severe hip fracture – March 2011 30 Jan, 2013
Hip fracture 19 percent less likely with just 4 ng higher level of vitamin D – Dec 2012 20 Dec, 2012
Hip fracture and vitamin D – Health ABC study – May 2012 28 Sep, 2012
Hip surgery followed by 100000 IU then 1000 IU of vitamin D daily – June 2010 31 Aug, 2012
2X to 3X higher hip fracture rate in Asia in past 30 years – Aug 2012 18 Aug, 2012
30 percent less chance of dying after hip fracture if take vitamin D and other drugs – 2011 24 Jun, 2012
Vitamin D 2nd most recommended way to prevent next hip fracture – Nov 2010 23 Jun, 2012
Hip fracture patients had only 16 ng of vitamin D – May 2011 23 Jun, 2012
Declining hip fracture rates in the United States – unknown reason – June 2010 23 Jun, 2012
Vitamin K1 reduced hip fracture but Vitamin K2 did not – Aug 2011 23 Jun, 2012
Calcium and vitamin D supplements after hip fracture reduced death rate by 25% – Feb 2011 19 Nov, 2011

20% of women will get a hip fracture in their lives

Estimation of the lifetime risk of hip fracture for women and men in Canada March 2012 FREE PDF doi: 10.1007/s00198-011-1652-8

Predict 30 day Hip fracture mortality – the only controllable variable is Vitamin D – Sept 2023

Emergency department prediction model for 30-day mortality after hip fracture: the Spanish National Hip Fracture Registry (RNFC) cohort
Hip Int . 2023 Sep 5;doi: 10.1177/11207000231197818
Javier Sanz-Reig 1, Jesus Mas-Martinez 1, Cristina Ojeda-Thies 2, Maria P Saez-Lopez 3 4, Noelia Alonso-García 5, Juan I Gonzalez-Montalvo 6 7

File is not an image.

Introduction: The aim of this study was to design and validate a predictive model for 30-day mortality in a cohort of patients from the Spanish National Hip Fracture Registry (RNFC) with variables collected at the Emergency Department.

Methods: Retrospective study of a prospective database of hip fracture patients ⩾75 years old between 1 January 2017 and 30 September 2019. Patient characteristics, type of fracture and osteoprotective medication were collected at the Emergency Department. Univariate analysis compared the results between patients alive and deceased 30 days after hospital discharge.
The variables associated with 30-day mortality in the regression analysis were

  • age >85 years,
  • male sex,
  • indoors pre-fracture mobility,
  • Dementia,
  • ASA score >3,
  • pathological fracture, and
  • vitamin D intake. Yes/No

A score scale was created with these variables. Discriminative performance was assessed using the area under the curve (AUC), calibration was assessed by applying Hosmer-Lemeshow goodness-of-fit test and predicted-to-observed mortality was compared.

Results: A total of 29,875 hip fracture cases were included in the study. The 30-day mortality of the overall cohort was 7.7%. A scale of 0-9 points was created, with a cut-off point of 4 points for the determination of patients at high risk of mortality. The AUC was 0.886. RNFC score presented good level of calibration (p = 0.139). The predicted-to-observed ratio was 1.09.

Conclusions: The RNFC predictive model with variables collected at the Emergency Department showed an excellent predictive capacity for 30-day mortality in patients after hip fracture.

PDF can be viewed on DeepDyve

Hip fracture deaths 3X more likely in one year if low vitamin D – Feb 2023

Preoperative Vitamin D Deficiency is Associated with Increased One-Year Mortality in Chinese Geriatric Hip Fracture Patients - A Propensity Score Matching Study
Clin Interv Aging . 2023 Feb 18;18:263-272. doi: 10.2147/CIA.S395228.
Guangtao Fu # 1, Rongjie Wu # 1 2, Ruiying Zhang # 1, Duanyong Chen 1, Haotao Li 1, Qiujian Zheng 1 3, Yuanchen Ma 1

Background: Vitamin D deficiency is a common comorbidity in geriatric hip fracture patients. However, there is still an ongoing debate regarding the influence of preoperative Vitamin D status on postoperative mortality in hip fracture patients.

Methods: Elderly patients (=60 years) who underwent surgical interventions for unilateral hip fracture from 2015 to 2020 in our center were included. We retrospectively retrieved the demographic data from the electronic medical database. Preoperative serum total 25-hydroxy-Vitamin D was set as the independent variable and patients were classified as the Vitamin D deficiency (<20ng/mL) and the control groups consequently. Clinical outcomes include all-cause mortality, walking ability, and major postoperative complications in the first postoperative year. Propensity score matching (PSM) was performed in a ratio of 1:1 in the two groups for further comparison.

Results: A total of 210 patients were included and 121 patients (57.6%) were diagnosed with Vitamin D deficiency. Patients in the Vitamin D deficiency group were much older and therefore preferred peripheral nerve block, and had significantly higher proportions of females, preoperative dementia, higher ASA grade, and lower baseline serum albumin level. Overall, 79 patients were identified in the Vitamin D deficiency and control groups after PSM, respectively.
Patients diagnosed with Vitamin D deficiency showed a significantly higher one-year mortality (21.5% vs 6.3%, P=0.011) and a much lower one-year independent walking rate (67.1% vs.84.8%, P=0.016) after the matching. Regarding the dataset before PSM and after PSM, the AUC for serum Vitamin D for predicting one-year mortality was 0.656 (P=0.006) and 0.695 (P=0.002), respectively.

Conclusion: Our retrospective PSM-design study provides new evidence that Vitamin D deficiency was associated with a significantly higher mortality and poor walking ability in the first year after surgical intervention based on southern Chinese populations.
 Download the PDF from VitaminDWiki

25 Pages listed in BOTH the categories Falls/Fracture and Meta-analysis

12 Pages listed in BOTH the categories Falls/Fracture and infants/Children

24 Falls/Fracture Intervention trials

All Falls and Fractures articles

Falls & Fractures Associated with: Bone - Health 28, Intervention 24, Osteoporosis 16, Seniors 14, Infant-Child 11, Vitamin K 9, Intervention - non-daily 9, ...

Cost savings 8 Calcium 7 Parkinson 7 Mortality 6 Magnesium 5 Trauma and surgery 5 Sports 5 Cardiovascular 5 Women 5   as of Feb 2024

Falls and Fractures        
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20072 Hip mortality.jpg admin 06 Sep, 2023 37.84 Kb 67
19302 3X hip fracture death_CompressPdf.pdf admin 27 Feb, 2023 373.84 Kb 211