Inverse Relationship between Metabolic Syndrome and 25-Hydroxyvitamin D Concentration in Elderly People without Vitamin D deficiency
Scientific Reports volume 8, Article number: 17052 (2018) https://doi.org/10.1038/s41598-018-35229-2
Chun-Min Wang, Chin-Sung Chang, Yin-Fan Chang, Shin-Jiuan Wu, Ching-Ju Chiu, Meng-Tzu Hou, Chuan-Yu Chen, Ping-Yen Liu & Chih-Hsing Wu
- Overview Metabolic Syndrome and vitamin D
- Metabolic Syndrome 13 percent more likely for every 10 ng less vitamin D – Meta-analysis Jan 2014
- Metabolic Syndrome 2.5 X more likely if less than 25 ng of vitamin D – Oct 2018
- Metabolic Syndrome risk increases about 70 percent if poor Vitamin D Receptor
- Metabolic syndrome 1.9 X more likely if senior women had less than 30 ng of Vitamin D – Oct 2017
- Upsurge in Metabolic diseases may be due to low vitamin D – May 2016
- Metabolic Syndrome risk reduced 44 percent when vitamin D levels increased by 30 nanograms – Aug 2015
- Incidence of 22 health problems related to vitamin D have doubled in a decade - with charts
Metabolic Syndrome 250 %, Hypertension (women) 160 %,Diabetes 66 %
In addition to Vitamin D
Download the PDF from VitaminDWiki
Vitamin D vs number of Metabolic Syndrome Features
Note: Could not find a list of the 5 MS features
Vitamin D status is inversely associated with the prevalence of metabolic syndrome (MetS). Whether this is true in the elderly without vitamin D deficiency is rarely investigated. Our data source is a cross-sectional survey of 1,966 community-dwelling elderly Taiwanese in 2012. An overnight fasting blood were obtained for biochemistry variables. Vitamin D deficiency was defined as serum 25-hydroxyvitamin D3 [25(OH)D] concentration <20 ng/mL. MetS is defined using modified ATP-III criteria. Of 523 participants without vitamin D deficiency (Men/Women = 269/254, age = 76.0 ± 6.2 years old [65–102 years old]), mean 25(OH)D was 44.0 ± 11.1 ng/mL, and the MetS prevalence of MS was 46.5%. Serum 25(OH)D was negatively associated with osteocalcin, the homeostatic model assessment insulin resistance (HOMA-IR) index, body mass index (BMI), and glycated hemoglobin A1c. Participants with more MetS features have lower serum 25(OH)D and osteocalcin. Binary logistic regression models showed that 25(OH)D, physical activity, and osteocalcin were negatively independent MetS factors, but that the HOMA-IR index, BMI, and being female were positively independent factors. The risk of MetS was progressively lower along with the increased 25(OH)D concentration, even above 60 ng/mL. In conclusion, a low 25(OH)D concentration is an independent risk factor for MetS in elderly people without vitamin D deficiency.
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