Magnesium in depression.
Pharmacol Rep. 2013;65(3):547-54.
Serefko A, Szopa A, Wlaź P, Nowak G, Radziwoń-Zaleska M, Skalski M, Poleszak E.
Chair and Department of Applied Pharmacy, Medical University of Lublin, Chodźki 1, PL 20-093 Lublin, Poland. ewa.poleszak at umlub.pl; michal.skalski at wum.edu.pl.
Magnesium is one of the most essential mineral in the human body, connected with brain biochemistry and the fluidity of neuronal membrane. A variety of neuromuscular and psychiatric symptoms, including different types of depression, was observed in magnesium deficiency. Plasma/serum magnesium levels do not seem to be the appropriate indicators of depressive disorders, since ambiguous outcomes, depending on the study, were obtained. The emergence of a new approach to magnesium compounds in medical practice has been seen.
Apart from being administered as components of dietary supplements, they are also perceived as the effective agents in treatment of
- migraine,
- alcoholism,
- asthma,
- heart diseases,
- arrhythmias,
- renal calcium stones,
- premenstrual tension syndrome etc.
Magnesium preparations have an essential place in homeopathy as a remedy for a range of mental health problems. Mechanisms of antidepressant action of magnesium are not fully understood yet. Most probably, magnesium influences several systems associated with development of depression. The first information on the beneficial effect of magnesium sulfate given hypodermically to patients with agitated depression was published almost 100 years ago. Numerous pre-clinical and clinical studies confirmed the initial observations as well as demonstrated the beneficial safety profile of magnesium supplementation. Thus, magnesium preparations seem to be a valuable addition to the pharmacological armamentarium for management of depression.
Table in the PDF
PMID: 23950577
PDF is attached at the bottom of this page
See also VitaminDWiki
- Overview Magnesium and vitamin D
- Depression is associated with low Magnesium – meta-analysis April 2015
- Magnesium and Vitamin D category listing has
369 items along with related searches - Depression category listing has
268 items along with related searches Pages listed in BOTH the categories Magnesium AND Depression
- Anxiety, depression, and suicide have recently surged (Note: Vitamin D, Omega-3, and Magnesium help) – May 2022
- Mental health not helped by vitamin D monotherapy (adding Omega-3 and Magnesium help) – review Nov 2021
- Weekly Vitamin D plus daily Magnesium is great (reduced depression in obese women in this case) – July 2021
- Depression treatments: diet, exercise, bright light, Vitamin D, B12, Omega-3, Zinc, Music, etc. – May 2019
- Depression treated by Omega-3, Magnesium, Zinc, probiotics, etc - Sept 2017
- Magnesium Puts Psychiatric Drugs to Shame for Depression – March 2019
- Dr. Coimbra discusses Vitamin D, Magnesium, Folic Acid, B12, Autism, Depression, etc – Sept 2018
- Magnesium in Healthcare (Rickets, Stones, Pregnancy, Depression, etc.) with level of evidence – Sept 2017
- Depression greatly reduced by taking 250 mg of Magnesium Chloride daily for 6 weeks– RCT June 2017
- MAGNESIUM IN MAN - IMPLICATIONS FOR HEALTH AND DISEASE – review 2015
- Depression is associated with low Magnesium – meta-analysis April 2015
- Depression is sometimes associated with low Magnesium – review 2013
- Magnesium reduces depression etc. – Aug 2013
- Depression, vitamin D, Magnesium: no agreement Jan 2012
See also web
- A Cure for Depression using Magnesium? huge web page
Which has the following chart
Magnesium reduces depression etc. – Aug 20139145 visitors, last modified 14 Oct, 2015, This page is in the following categories (# of items in each category)Attached files
ID Name Uploaded Size Downloads 5538 Mg and depression.jpg admin 30 May, 2015 107.58 Kb 1195 2916 Magnesium, depresssion, etc.pdf admin 23 Aug, 2013 129.01 Kb 1705 - Depression category listing has