Miscarriage 2.5X more likely if second-hand smoke and low vitamin D – Sept 2022

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Maternal Passive Smoking, Vitamin D Deficiency and Risk of Spontaneous Abortion

Nutrients 2022, 14(18), 3674; https://doi.org/10.3390/nu14183674
by Shiqi Lin 1, Jiajia Li 1, Yuan Zhang 2, Xinming Song 1, Gong Chen. 1 and Lijun Pei

• 1 Institute of Population Research and China Center on Population Health and Development, Peking University, Beijing 100871, China
• 2 National Research Institute for Health and Family Planning, Beijing 100081, China

Background: Maternal passive smoking and vitamin D deficiency might elevate risk of spontaneous abortion. The study aimed to investigate the association of co-exposure to passive smoking and vitamin D deficiency with the risk of spontaneous abortion.

Methods: A population-based case-control study was performed among non-smoking women in Henan Province, China, with 293 spontaneous abortion cases and 496 liveborn controls with term, normal birthweight.

Results: Compared to women without exposure to passive smoking nor vitamin D deficiency, women with deficient vitamin D alone and women with exposure to passive smoking alone had increased risk of spontaneous abortion (OR = 1.76, 95%CI: 1.08~2.89; OR = 1.73, 95%CI: 1.11~2.69, respectively).
The risk of spontaneous abortion was even higher for those with co-exposure to passive smoking and vitamin D deficiency (OR = 2.50, 95%CI: 1.63~3.84). A dose-response relationship was found of an incremental risk of spontaneous abortion with rising numbers of exposures to passive smoking and vitamin D deficiency (p < 0.001).

Conclusion: Co-exposure to passive smoking and vitamin D deficiency was associated with an elevated risk of spontaneous abortion, and the risk of spontaneous abortion rose with rising numbers of exposures. Intervention programs need to specifically target the vulnerable groups of pregnant women with both malnutrition and unfavorable environmental exposure.
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VitaminDWiki - Low Vitamin D is worse for your health than smoking

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VitaminDWiki - Miscarriage and low Vitamin D – many studies

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VitaminDWiki - Pregnancy category contains

922 items in Pregnancy category

 - see also

• Overview Pregnancy and vitamin D
• Number of articles in both categories of Pregnancy and:Dark Skin 30;   Depression 21;   Diabetes 44;   Obesity 17;  Hypertension 44;   Breathing 35;  Omega-3 44;  Vitamin D Receptor 24 Click here for details
• All items in category Infant/Child 854 items
• Pregnancy needs at least 40 ng of vitamin D, achieved by at least 4,000 IU – Hollis Aug 2017
• 38+ papers with Breastfed etc, in the title
• Call to action – more Vitamin D for pregnancies, loading doses are OK – Holick Aug 2019
• 53+ preeclampsia studies
• 94+ studies with PRETERM in the title
• Fertility problem (PCOS) reduced by vitamin D, etc: many studies 15+
• 94+ Gestational Diabetes
• Caesarean birth much more likely if low Vitamin D - many studies 15+ studies
• Post-partum depression and low Vitamin D - many studies 15+ studies
• Stillbirth reduced by Vitamin D, Zinc, Omega-3 - several studies 5+ studies
• Search VitaminDWiki for "Assisted reproduction" 33 items as of Aug 2022
• Fertility and Sperm category listing has 142 items along with related searches
• (Stunting OR “low birth weight” OR LBW) 1180 items as of June 2020
• Less labor pain if higher level of vitamin D – August 2021
• Healthy pregnancies need lots of vitamin D
• Ensure a healthy pregnancy and baby - take Vitamin D before conception
  

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VitaminDWiki - Smoking reduces vitamin D - many studies contains

Two pathways are often proposed for how smoking decreases vitamin D:
   1) Smoking decreases Calcium. and Vitamin D is used up in replacing the Calcium
   2) Smoking injures the body, and vitamin D is used up in repairing the body
It appears that taking Vitamin D while smoking will:
   1) Decrease the incidence of the many health problems associated with smoking - even lung cancer
   2) Decrease the desire to smoke (perhaps take fewer smoking breaks?)
   3) Increase breathing capacity
Opinion: If you must smoke, have recently smoked, or are getting 2nd hand smoke:
   take Vitamin D and perhaps Omega-3
    They will extinguish much of the inflammation caused by inhaling tobacco smoke.
Vitamin D should also help people quit smoking
   1) Reduces weight gain associated with quitting smoking
   2) Reduces depression associated with quitting smoking