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Time-release form of active vitamin D granted a patent for chronic kidney disease – July 2014

OPKO Granted Patent from US Patent & Trademark Office for RAYALDEE

Treat secondary hyperparathyroidism in patients with stage 3 or 4 chronic kidney disease (CKD) and vitamin D insufficiency.
US Pat. No. 8,778,373

Notes by VitaminDWiki

Standard vitamin D is not available to much of the body when the kidney is not working
Standard active vitamin D has a very short half life, so time release form should be an excellent improvement - see other options below

See also VitaminDWiki

Calcitriol category listing has 62 items along with related searches
Vitamin D3 vs serum D3 (Calcitriol, HyD) – Jan 2012
Vitamin D3 becomes Calcidiol which becomes Calcitriol
Nano-encapsulated of Vitamin D3, Calcidiol, calcitriol look promising, esp time release – Dec 2012 7 day!!
Overview Kidney and vitamin D
Getting Vitamin D into your body
Modified release active Vitamin D (calcifediol ) for those with poor Kidney function (USD 10,000 per year) – April 2015

See also web

Modified-Release Calcifediol Corrects Vitamin D Deficiency, Secondary Hyperparathyroidism in Chronic Kidney Disease Nov 2014
They found Modified-Release Calcifediol did much better than a placebo. Apparently did not test it against Vitamin D
Modified-release oral calcifediol corrects vitamin D insufficiency with minimal CYP24A1 upregulation Nov 2014
Download the PDF from VitaminDWiki.
One of many charts in the PDF

Time-release form of active vitamin D granted a patent for chronic kidney disease – July 2014

10221 visitors, last modified 26 Jul, 2015,

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Links to this page
- Getting Vitamin D into your body Vitamin D3 becomes Calcidiol which becomes Calcitriol Kidney disease helped by active or high dose Vitamin D - Feb 2014 Chronic Kidney Disease study not aware of appropriate forms of vitamin D – March 2014 Modified release active Vitamin D (calcifediol ) for those with poor Kidney function (USD 10,000 per year) – April 2015 Vitamin D trial for COVID-19 – using their patented slow-release form – Aug 2021 Nanoparticles could be used to increase vitamin D getting to the gut – Oct 2015 Nano-encapsulated of Vitamin D3, Calcidiol, calcitriol look promising, esp time release – Dec 2012 Vitamin D3 vs serum D3 (Calcitriol, HyD) – Jan 2012 Not as much active vitamin D if poor kidney function and low vitamin D – March 2015 Vitamin D and chronic kidney disease – July 2014

This page is in the following categories (# of items in each category)

Kidney 209 Calcitriol 62

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Attached files

ID	Name	Comment	Uploaded	Size	Downloads
4620	MR.jpg		admin 22 Nov, 2014	52.87 Kb	1306
4619	modified release.pdf	PDF 2014	admin 22 Nov, 2014	405.68 Kb	1680

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