Senior men with good vitamin D exercised more and had less metabolic syndrome – May 2023

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Healthy lifestyles are associated with better vitamin D status in community-dwelling older men: The Health In Men Study (HIMS)

Clin Endocrinol (Oxf) . 2023 May 10. doi: 10.1111/cen.14926
Xiaoying Liu 1, Kaye E Brock 1, Tara C Brennan-Speranza 1, Leon Flicker 2 3, Jonathan Golledge 4 5, Graeme J Hankey 2 6, Christian M Girgis 1 7, Bu B Yeap 2 8

Objective: Older people are more prone to vitamin D deficiency than younger populations. Individual lifestyle factors have been associated with vitamin D status. We examined the influence of a combination of lifestyle factors on vitamin D status in older men.

Participants and measurements: In a population-based cohort study of older men (age ≥65 years), a lifestyle score was calculated from eight prudent health-related behaviours (smoking, exercise, alcohol, fish and meat consumption, adding salt, milk choices and obesity) collected via questionnaire at baseline. Blood samples were collected 5 years afterwards to measure plasma 25-hydroxyvitamin D (25OHD) levels. Associations between lifestyles and the likelihood of having plasma 25OHD levels of ≥75 versus <75 nmol/L and ≥50 versus <50 nmol/L were tested using logistic regression models.

Results: Of the 2717 men analysed, mean plasma 25OHD was 69.0 ± 23.5 nmol/L, with 20.7% having plasma 25OHD <50 nmol/L. Men engaging in ≥4 healthy lifestyle behaviours had 20% higher odds of plasma 25OHD ≥75 nmol/L (adjusted OR = 1.20, 95% CI: 1.01-1.45) compared to those with <4 healthy behaviours. No association was found for 25OHD ≥50 nmol/L.
Higher physical activity was the only individual component significantly associated with vitamin D sufficiency (highest vs. lowest quintiles of physical activity, adjusted OR = 2.01, 95% CI: 1.47-2.74 for 25OHD ≥50 nmol/L, adjusted OR = 2.35, 95% CI: 1.81-3.06 for 25OHD ≥75 nmol/L).

Conclusion: Multiple healthy lifestyle behaviours are associated with better vitamin D status in older men. Further work is needed to determine the effects of promoting healthy lifestyle behaviours, including physical activity, on vitamin D sufficiency.
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VitaminDwiki – Metabolic Syndrome contains

106 items

See also

• Overview Metabolic Syndrome and vitamin D
• Overview Diabetes and vitamin D
• Overview Obesity and Vitamin D
• Diabetes, Metabolic Syndrome and Magnesium - many studies
• Arteries and Atherosclerosis and Vitamin D - many studies
• Metabolic Syndrome risk decreases by 20 percent with each 10 ng increase in Vitamin D - April 2021
• Metabolic Syndrome and Vitamin D - review of 33 studies - March 2021
• Metabolic Syndrome far less likely if high Vitamin D – 3 meta-analyses 2021
• Metabolic Syndrome 11X more likely if have a poor Vitamin D Receptor – 2018
• Vitamin D is linked to metabolic syndrome and obesity – Aug 2019
• Risk of Metabolic syndrome for senior women reduced 42 percent by 1,000 IU of vitamin D – RCT June 2019
• Metabolic Syndrome risk reduced 3.7 X by nuts (Magnesium, Omega-3) – Dec 2018
• Metabolically Healthy – only 1 in 50 seniors in the US – Nov 2018
• Metabolic Syndrome indicators inversely proportional to vitamin D below 46 ng – Nov 2018
• Metabolic Syndromes fought by Vitamin D in 6 ways – Oct 2023
  

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Metabolic Syndrome Associations with other categories

 Obesity 19;  Diabetes 15;  Cardiovascular 12;  Magnesium 8;  Seniors 8;  Women 5; 5;  Hypertension 5;  Intervention 5;  Omega-3 4;  Youth 4;  Meta-analysis 4

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