Nutritional rickets: calcium or vitamin D deficiency? – Editorial
The American Journal of Clinical Nutrition, nqab121, https://doi.org/10.1093/ajcn/nqab121
Roger Bouillon
Sempos et al. (1) in the present issue of the American Journal of Clinical Nutrition studied the interaction between vitamin D status [defined by serum concentration of 25-hydroxyvitamin D or 25(OH)D] and calcium intake in Nigerian children with rickets. They observed that a serum concentration of 25(OH)D below 47.5 (possibly even 65) nmol/l was associated with an increased risk of rickets in children with a very low calcium intake (about 200 mg/d). Indeed, the calcium intake of the ricketic children was similar to that of healthy controls, whereas serum 25(OH)D strongly discriminated between both groups. This 25(OH)D threshold is much higher than the one [25–30 nmol/L (2–4...
See also VitaminDWiki
There is a lot of discussion as to how much Vitamin D is needed to treat each health problem
- Saudi study defines normal Vitamin D level to be 50 to 70 ng (diabetes, etc.) - June 2020
- More than 30 ng of vitamin D is sometimes needed (Kidney needs 50 ng) – March 2019
- Vitamin D is needed for human fertility – goal is 50 ng – Sept 2018
- Optimum Vitamin D for bones might be 40 ng – Oct 2014
- Is 50 ng of vitamin D too high, just right, or not enough
- has the following - click on image for details
Overview of Rickets and vitamin D contains the following summary
Rate of rickets is usually < 0.1% of births, unless dark skin, breastfed, preemie, twin, Mongolian, or Russian
Rate of rickets has greatly increased with the drop in vitamin D levels during the past 40 years
400 IU can prevent/treat most rickets Turkey gave vitamin D to EVERY child and eliminated Rickets
Can have rickets without a low serum level of vitamin D (~20% of the time)
Giving enough Vitamin D to the mother (before and after birth) PREVENTS most forms of Rickets
Rate of rickets in some countries varies from 10% to 70% (typically poor health overall)
Rickets has been more than doubling in many countries
Rickets is strongly associated with severe breathing problems (weak ribs)
Bowed legs is not the primary indication of rickets (3 other indications of rickets are seen more often)
Rickets is typically due to low cellular Vitamin D - April 2024
Some Rickets is due to poor genes - Vitamin D needed lifelong – June 2020
Vitamin D and Rickets consensus took 80 years
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