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Low Vitamin D in Mongolia, supplementing would save lives (20 percent have rickets) – Oct 2019

A Review of the Potential Benefits of Increasing Vitamin D Status in Mongolian Adults through Food Fortification and Vitamin D Supplementation

Nutrients 2019, 11(10), 2452; https://doi.org/10.3390/nu11102452
William B. Grant 1,* and Barbara J. Boucher 2

  • 1 Director, Sunlight, Nutrition, and Health Research Center, P.O. Box 641603, San Francisco, CA 94164-1603, USA
  • 2 The Blizard Institute, Barts & The London School of Medicine & Dentistry, Queen Mary University of London, 4 Newark Street, London E12AT, UK
VitaminDWiki

Dr. Grant on vitamin D and mortality in VitaminDWiki

Overview of Rickets and vitamin D contains the following

Rate of rickets is usually < 0.1% of births, unless dark skin, breastfed, preemie, twin, Mongolian, or Russian
Rate of rickets has greatly increased with the drop in vitamin D levels during the past 40 years
400 IU can prevent/treat most rickets Turkey gave vitamin D to EVERY child and eliminated Rickets
Can have rickets without a low serum level of vitamin D (~20% of the time)
Giving enough Vitamin D to the mother (before and after birth) PREVENTS most forms of Rickets
Rate of rickets in some countries varies from 10% to 70% (typically poor health overall)
Rickets has been more than doubling in many countries
Rickets is strongly associated with severe breathing problems (weak ribs)
Bowed legs is not the primary indication of rickets    (3 other indications of rickets are seen more often)
Rickets is typically due to low cellular Vitamin D - April 2024
Some Rickets is due to poor genes - Vitamin D needed lifelong – June 2020
Vitamin D and Rickets consensus took 80 years

Rickets category has 127 items

Mongolia

This study concluded that TB is not treated by Vitamin D

TB is helped by Vitamin D, provided enough is given and Vitamin D receptor activation is increased

Reference #63: High-Dose Vitamin D3 during Tuberculosis Treatment in Mongolia. A Randomized Controlled Trial
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Study found that those with poor VDR were 2X more likely to have TB
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Overview Tuberculosis and Vitamin D has the following summary

Many studies have found that Vitamin D both PREVENTS and TREATS TB

TB and vitamin D 125 items

Items in both categories TB and Vitamin D Receptor gene are listed here:


A poor VDR increases the risk of 54 health problems (such as TB)  click here for details

Items in both categories TB and Radomized Controlled Trials are listed here:

Items in both categories TB and Meta-analysis are listed here:

Vitamin D treats other health problems as well - such as:

COPD fought by Vitamin D - many studies

Overview Stroke and vitamin D

Overview Kidney and vitamin D contains the following summary

 Download the PDF from VitaminDWiki
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   *Deaths/100,000 population ( Population = 3 million, so total deaths are 30X higher)

Serum 25-hydroxyvitamin D (25(OH)D) concentrations are low in Mongolia, averaging 22 ng/mL in summer and only 8 ng/mL in winter. Mongolians have high incidence and/or prevalence of several diseases linked to low 25(OH)D concentrations, including ischemic heart disease, malignant neoplasms, cirrhosis of the liver, ischemic stroke, lower respiratory tract infections, preterm birth complications, and diabetes mellitus. Fortifying regularly consumed foods such as flour, milk, and edible oils with vitamin D3 could raise 25(OH)D concentrations by about 10 ng/mL.
However, to achieve 25(OH)D concentrations of 30–40 ng/mL in adults, vitamin D intakes of 1000 to 4000 IU/day would be required, making personal supplement use necessary. On the basis of prospective observational studies and clinical trials of disease incidence or known mortality rates and adverse pregnancy and birth outcomes, raising mean serum 25(OH)D concentrations to 40 ng/mL would likely reduce incidence and mortality rates for those and other diseases, reduce the rate of adverse pregnancy and birth outcomes, and increase mean life expectancy by one year or more.

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Low Vitamin D in Mongolia, supplementing would save lives (20 percent have rickets) – Oct 2019        
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