Prenatal or Childhood Serum Levels of Vitamin D and Dental Caries in Paediatric Patients: A Systematic Review.
Oral Health & Preventive Dentistry, 03 Sep 2020, 18(1):653-667, DOI: 10.3290/j.ohpd.a45089
Carvalho Silva C, Mendes R, Manso MDC, Gavinha S, Melo P
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PURPOSE:To assess the association between low prenatal or childhood levels of 25-hydroxyvitamin D (25(OH) D) and dental caries experience in children. MATERIALS AND
METHODS:PubMed, B-On, Web of Science, Scopus, and Cochrane Library databases were searched. The inclusion criteria were randomised controlled trials, cohort and cross-sectional studies published between 1998 and 2019; caries outcomes expressed as prevalence or based on the decayed missing and filled index for primary and permanent teeth/surfaces; and vitamin D levels assessed by laboratory analysis. Two authors independently selected studies, collected data, and assessed risk of bias. The quality of the studies was also assessed. A narrative synthesis of the studies was performed without quantitative pooling of data due to clinical and methodological heterogeneity.
RESULTS:Out of 399 studies identified, 13 were included in the data synthesis. Even though many of the included studies had a cross-sectional design, 11 were considered high quality. The studies indicated that vitamin D has an important role in caries experience, but also revealed that vitamin D levels equal to or above 75 nmol/l seem to be more closely related to caries experience than the reference value of the Institute of Medicine.
CONCLUSION:Evidence of an association exists between low 25(OH) D levels (<75 nmol/l) and caries experience in children. Hence, low vitamin D levels should be considered a potential factor associated with caries in children. Clinicians should be aware that good prenatal nutrition and early childhood diet might influence caries experience.
21 Items in both categories Dental and Infant/Child:
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Upper canine teeth extracted faster if take Calcitriol (a form of Vitamin D) - RCT Feb 2025
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Childhood Dental Caries about 2X more likely if Vitamin D is less than 20 ng – review April 2024
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Early Childhood Caries 1.4 times more likely if 20-30 ng of Vitamin D – meta-analysis Jan 2024
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Caries in deciduous teeth about 2X more likely if low vitamin D – Review Nov 2023
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Severe infant caries 10X higher risk if low vitamin D (under 14 ng) - Dec 2021
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Virtually all infants in Poland got 400 IU of Vitamin D daily (not enough, non-daily is better) – April 2021
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More dental caries in children who have less than 30 ng of Vitamin D – Review Sept 2020
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Vitamin D cut dental caries in half in 1930's – meta-analysis 2013
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Teeth from 19th century London indicate that most children were Vitamin D Deficient - Oct 2019
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Half as many tooth enamel defects in child if 2400 IU Vitamin D in late pregnancy – RCT Aug 2019
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Half as many teeth problems if higher cord blood level of vitamin D – March 2019
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No tooth decay in children with adequate Vitamin D (small study) – June 2018
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Early tooth decay 1.9 X more likely if a poor Vitamin D receptor – July 2017
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Severe childhood dental problems 2.4 X more likely if breastfed for more than two years (low vitamin D) – June 2017
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Dental Caries risk in children cut in half if more than 20 nanogram of Vitamin D – Nov 2015
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Teeth enamel problems (MIH) 11 percent less likely with just 4 ng more vitamin D – Dec 2014
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3X fewer infant dental caries if good level of vitamin D while pregnant – April 2014
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Severe tooth decay in children unless supplemented with Vitamin D drops – Oct 2013
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UVB added in classroom reduced cavities, increased height, increased academics. etc
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Dental caries cut in half by vitamin D, review of 24 old clinical trials – Nov 2012
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Children with severe caries were 2X more likely to have inadequate vitamin D – July 2012
There have been 3199 visits to this page
More dental caries in children who have less than 30 ng of Vitamin D – Review Sept 2020
87 visitors, last modified 08 Jun, 2025,
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Printer Friendly
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This page is in the following categories (# of items in each category)
- Upper canine teeth extracted faster if take Calcitriol (a form of Vitamin D) - RCT Feb 2025
- Childhood Dental Caries about 2X more likely if Vitamin D is less than 20 ng – review April 2024
- Early Childhood Caries 1.4 times more likely if 20-30 ng of Vitamin D – meta-analysis Jan 2024
- Caries in deciduous teeth about 2X more likely if low vitamin D – Review Nov 2023
- Severe infant caries 10X higher risk if low vitamin D (under 14 ng) - Dec 2021
- Virtually all infants in Poland got 400 IU of Vitamin D daily (not enough, non-daily is better) – April 2021
- More dental caries in children who have less than 30 ng of Vitamin D – Review Sept 2020
- Vitamin D cut dental caries in half in 1930's – meta-analysis 2013
- Teeth from 19th century London indicate that most children were Vitamin D Deficient - Oct 2019
- Half as many tooth enamel defects in child if 2400 IU Vitamin D in late pregnancy – RCT Aug 2019
- Half as many teeth problems if higher cord blood level of vitamin D – March 2019
- No tooth decay in children with adequate Vitamin D (small study) – June 2018
- Early tooth decay 1.9 X more likely if a poor Vitamin D receptor – July 2017
- Severe childhood dental problems 2.4 X more likely if breastfed for more than two years (low vitamin D) – June 2017
- Dental Caries risk in children cut in half if more than 20 nanogram of Vitamin D – Nov 2015
- Teeth enamel problems (MIH) 11 percent less likely with just 4 ng more vitamin D – Dec 2014
- 3X fewer infant dental caries if good level of vitamin D while pregnant – April 2014
- Severe tooth decay in children unless supplemented with Vitamin D drops – Oct 2013
- UVB added in classroom reduced cavities, increased height, increased academics. etc
- Dental caries cut in half by vitamin D, review of 24 old clinical trials – Nov 2012
- Children with severe caries were 2X more likely to have inadequate vitamin D – July 2012
There have been 3199 visits to this page
More dental caries in children who have less than 30 ng of Vitamin D – Review Sept 2020
87 visitors, last modified 08 Jun, 2025,
(Cached)
Printer Friendly
Follow this page for updates
This page is in the following categories (# of items in each category)
| 87 visitors, last modified 08 Jun, 2025, |