Vitamin D levels might be raised very quickly

Quickly raising Vitamin D levels has been proven to

        Save lives,     Reduce pain,     Reduce ICU & hospital time/costs

• Sepsis is both prevented and treated by Vitamin D - many studies

• Ventilator-associated pneumonia death rate cut in half by Vitamin D injection (300,000 IU) – RCT July 2017

• ICU cost reduced by at least 27,000 dollars if get high dose vitamin D in first week - April 2017

• Vitamin D and Glutamine reduced Trauma Center deaths by half – Matthews March 2017

• 18 fewer hospital days if given 500,000 IU of vitamin D while ventilated in ICU – RCT June 2016

• ICU survival increased with vitamin D single 540K IU loading dose - JAMA Sept 2014

• Vitamin D deficiency in pediatric critical illness: Time to move on from observational studies – Nov 2016

• Flu stopped in 2-3 days by a single 50,000 IU dose of vitamin D

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Proven ways which take 2 days & possible ways which might take 2 hours

Injection

Proven to raise vitamin D levels in 2 days with a single injection of standard vitamin D into muscle

Possibly faster if inject into multiple locations at the same time

Possibly faster if inject multiple times over a 3 day period

Possibly faster if inject near to trauma location (exploiting local paracrine and autocrine activation)

Intravenous - possible

Inject directly into blood (should be faster than injection into the muscle)

Oral Loading dose

Proven to raise Vitamin D levels in 3-5 days

150,000 IU seem to respond in 1 day

Topical loading dose near trauma site

Vitamin D is quickly absorbed thru the skin and becomes activated locally, without needing liver and kidney

Apply as a spray or liquid

DMSO might speed it up

Nanoemulsion appears to be good

Sublingual loading dose

20-30 sprays of 6,000 IU per spray - under the tongue, inside cheek

Standard form - nanoemulsion may be much faster

Which form should be used when?

Oil-based and Water-based forms probably have similar response times

Semi-activated (Calcidiol) - probably get benefits sooner - perhaps 12 hours

• Calcifediol soft capsules US Patent application]

• 

• Note: In many countries Calcidiol is available only by prescription - which can take many days

Fully-activated (Calcitriol)- probably get benefits sooner

• probable prescription delay as above

Nanoemulsion swished in the mouth or topical appears to create a response in just a few hours

Magnesium might speed-up the healing

The body requires Magnesium during 8 stages of Vitamin D processing

Having an adequate level of Magnesium might speed up processing

A majority of people are low in both Magnesium and Vitamin D

Magnesium injections have been routine in hospitals for decades

Should consider giving Magnesium as an injection or orally when getting emergency Vitamin D

Non-emergency - raise the vitamin D level in a week or so

Scheduled surgery

Chronic pain/health problem which wants to be treated in days, not months

Pregnancy - many fetal deaths and infant problems can be avoided if have good level of vitamin D during the 1st trimester, vsthe 2nd trimester

Future? spray vitamin D during surgery

I anticipate that Vitamin D will be applied to many body tissues in future surgeries

As of 2017 topical Vitamin D has improved tooth transplants in dogs

Future: Other transplants, spinal cord surgery, wounds, sutures, bone healing. . .

    perhaps even have suture thread covered with Vitamin D