Topical Vitamin D provides more benefits than oral sometimes - many studies

It appears that ~10% of people will benefit from Topical more than the Oral form of Vitamin D

It appears that ~20% of people having specific health problems will get more benefit from Topical than Oral

  • Preeclampsia. Food Allergy, PTSD, Ear infection, Infertility, MS, Colon Cancer, TB, Asthma, COPD, Epilepsy, Atrial Fibrillation. Liver

  • Also suspect for those people with poor guts: Cystic Fibrosis, Diabetes

    However, Topical forms of Vitamin D are:

  • 10X-100X more expensive

  • Harder to use than oral for most people

  • Do not easily allow high doses - for loading doses or non daily dosing (biweekly etc)

    • Vitamin D cream might be OK - 5 squirts of cream = 50,000 IU

    Most body tissues can fully activate Vitamin D locally (without the Liver and Kidneys)

    Tissues such as the skin, the inside of the cheeks, the lungs, and the nose

Some people have a poor vitamin D binding gene

  • Limits the amount of semi-activated Vitamin D from the liver

  • The vitamin D binding gene does not appear to limit vitamin D that is activated by tissue

    An increasing number of people have poor Vitamin D genes

  • Starting in the 1930's people with poor immune systems have been surviving due to better hygiene, antibiotics, vaccines, etc.

  • Since then, poor immune system genes have more frequently been passed on to future generations

  • Before there was "Survival of the Fittest", but there is "Survival of the Survivors"



43 reasons for Vitamin D deficiency includes the following chart

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VitaminDWiki – Topical Vitamin D category contains

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Topical Vitamin D sources include:

Vitamin D Binding Protein category in VitaminDWiki has items and starts with:

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Vitamin D Binding Protein list of health problems includes:

    Preeclampsia, Food Allergy, PTSD, Poor Response to Oral Vitamin D, Ear infection, Multiple Sclerosis, Colorectal Cancer, Prostate Cancer - blacks,

    Infertility. TB, Asthma, COPD, Epilepsy, Atrial Fibrilation, and Obesity

Getting Vitamin D into your blood and cells shows all of the sources

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Note: Vitamin D Binding protein does NOT restrict topical or sublinqual Vitamin D

Mystery of why UVB is better than oral supplementation resolved after 7 years
  • A 2012 study found that:
  • For years people speculated that the Sun/UVB produced something in addition to Vitamin D

  • But, studies have found many health problems, such as MS. to be assocated with poor genes:

    • MS studies and Vitamin D Binding Protein ( ), Vitamin D Receptor ( ), Genes ( )
  • Mystery solved: Oral and topical sources will produce same blood level, but topical will get more activated vitamin D to the tissues if poor VDBP

    Remaining mystery: Why does Vitamin D from UV last 2X longer in the body than from oral sources

  • Might there be a better storage location for UV or topical Vitamin D in tissue (muscle?)

  • Might non-UV, topical sources also have a 2X longer half-life in the body?


TOP articles in Forms of Vitamin D:

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4 Reasons why you have not heard that Vitamin D is good for the skin:

1) Vitamin D has been patented to help the skin - and companies do not want to pay royalties

It appears to cost >$30,000 to prepare, present, and defend a single health claim for a supplement

< year 2000 2019 increase
Drops 10 IU/drop 2,000 IU 200X
Capsule 200 IU 50,000 IU 250X

4) Doctors rarely suggest applying the Vitamin D directly to the skin

They often incorrectly believe that the Vitamin D must be first processed by the liver and the kidneys


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