Topical Vitamin D provides more benefits than oral sometimes - many studies
It appears that ~10% of people will benefit from Topical more than the Oral form of Vitamin D
It appears that ~20% of people having specific health problems will get more benefit from Topical than Oral
Preeclampsia. Food Allergy, PTSD, Ear infection, Infertility, MS, Colon Cancer, TB, Asthma, COPD, Epilepsy, Atrial Fibrillation. Liver
Also suspect for those people with poor guts: Cystic Fibrosis, Diabetes
However, Topical forms of Vitamin D are:
10X-100X more expensive
Harder to use than oral for most people
Do not easily allow high doses - for loading doses or non daily dosing (biweekly etc)
- Vitamin D cream might be OK - 5 squirts of cream = 50,000 IU
Most body tissues can fully activate Vitamin D locally (without the Liver and Kidneys)
Tissues such as the skin, the inside of the cheeks, the lungs, and the nose
Some people have a poor vitamin D binding gene
Limits the amount of semi-activated Vitamin D from the liver
The vitamin D binding gene does not appear to limit vitamin D that is activated by tissue
An increasing number of people have poor Vitamin D genes
Starting in the 1930's people with poor immune systems have been surviving due to better hygiene, antibiotics, vaccines, etc.
Since then, poor immune system genes have more frequently been passed on to future generations
Before there was "Survival of the Fittest", but there is "Survival of the Survivors"
43 reasons for Vitamin D deficiency includes the following chart

VitaminDWiki – Topical Vitamin D category contains
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Topical Vitamin D sources include:
Sun
UV - sunbed or make UV lamp at home
Topical Vitamin D oil
Topical Vitamin D cream Amazon 10.000 IU Amazon 15,000 IU
Topical Vitamin D water (open up and dissolve 50,000 IU powder in 1/2 tsp of water)
Keep Vitamin D water under tongue for a few minutes
Apply Vitamin D water to skin
Spray inside of the cheek or on the skin Amazon 100+ companies Oct 2019
Vitamin D patches Amazon, 5,000 IU in 8 hours
Inhaled Vitamin D - make at home
Note: Topical Vitamin D may also be BETTER than most oral forms if you:
Have Gut problems
Dislike swallowing pills
Have a low/poor blood level response to vitamin D supplementation- e.g., poor CYP27A1 gene (in your liver)
Have poor Vitamin D Binding Protein (in your blood)
Vitamin D Binding Protein category in VitaminDWiki has items and starts with:
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Vitamin D Binding Protein list of health problems includes:
Preeclampsia, Food Allergy, PTSD, Poor Response to Oral Vitamin D, Ear infection, Multiple Sclerosis, Colorectal Cancer, Prostate Cancer - blacks,
Infertility. TB, Asthma, COPD, Epilepsy, Atrial Fibrilation, and Obesity
Getting Vitamin D into your blood and cells shows all of the sources


Note: Vitamin D Binding protein does NOT restrict topical or sublinqual Vitamin D
Mystery of why UVB is better than oral supplementation resolved after 7 years
- A 2012 study found that:
For years people speculated that the Sun/UVB produced something in addition to Vitamin D
But, studies have found many health problems, such as MS. to be assocated with poor genes:
- MS studies and Vitamin D Binding Protein ( ), Vitamin D Receptor ( ), Genes ( )
Mystery solved: Oral and topical sources will produce same blood level, but topical will get more activated vitamin D to the tissues if poor VDBP
Remaining mystery: Why does Vitamin D from UV last 2X longer in the body than from oral sources
Might there be a better storage location for UV or topical Vitamin D in tissue (muscle?)
Might non-UV, topical sources also have a 2X longer half-life in the body?
TOP articles in Forms of Vitamin D:
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4 Reasons why you have not heard that Vitamin D is good for the skin:
1) Vitamin D has been patented to help the skin - and companies do not want to pay royalties
WO/2006/133829 USE OF 25-HYDROXY-VITAMIN D3 - cream for many skin problems
(WO/2006/094064) Sept 2006 METHOD OF REDUCING SCARS WITH VITAMIN D
WO/2011/019617 VITAMIN D3 AND ANALOGS THEREOF FOR TREATING ALOPECIA - delivered to the skin March 2011
Who said vitamin D could not be patented - VitaminDWiki
- A patent is one of the 22 Criteria to associate a health problem with low vitamin D in VitaminDWiki
2) FDA requires a LOT of data to allow a claim that a supplement can improve health
FDA allows 2 specific Vitamin D and 2 Omega-3 health claims - 2019
3) Only recently have Vitamin D doses been large enough to really help (200X)
| < year 2000 | 2019 | increase | |
| Drops | 10 IU/drop | 2,000 IU | 200X |
| Capsule | 200 IU | 50,000 IU | 250X |
4) Doctors rarely suggest applying the Vitamin D directly to the skin
They often incorrectly believe that the Vitamin D must be first processed by the liver and the kidneys