Teeth enamel problems (MIH) 11 percent less likely with just 4 ng more vitamin D

Elevated Serum 25(OH)-Vitamin D Levels Are Negatively Correlated with Molar-Incisor Hypomineralization.

J Dent Res. 2014 Dec 10. pii: 0022034514561657. [Epub ahead of print]

Kühnisch J1, Thiering E2, Kratzsch J3, Heinrich-Weltzien R4, Hickel R5, Heinrich J6; for the GINIplus study group; the LISAplus study group; for the GINIplus study group. Collaborators (49)

1Department of Conservative Dentistry and Periodontology, School of Dentistry, Ludwig-Maximilians-University of Munich, Munich, Germany jkuehn@dent.med.uni-muenchen.de.

2Institute of Epidemiology I, Helmholtz Zentrum Munich, German Research Centre for Environmental Health, Neuherberg, Germany Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.

3Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany.

4Department of Preventive and Paediatric Dentistry, Friedrich-Schiller-University of Jena, Jena, Germany.

5Department of Conservative Dentistry and Periodontology, School of Dentistry, Ludwig-Maximilians-University of Munich, Munich, Germany.

6Institute of Epidemiology I, Helmholtz Zentrum Munich, German Research Centre for Environmental Health, Neuherberg, Germany

To date, the precise etiology of molar-incisor hypomineralization (MIH) is uncertain. Vitamin D plays a key role in hard tissue formation. Therefore, this study aimed to analyze the relationship between serum 25-hydroxy-vitamin D (25(OH)D) status and dental health data obtained from 1,048 children in a 10-year follow-up of the Munich GINIplus and LISAplus birth cohorts. The dental examination included the diagnosis of MIH and recording of (non-)cavitated caries lesions in primary and permanent teeth. Serum 25(OH)D concentrations were taken from blood samples of the 10-year investigation and measured with a fully automated, modular system. Different logistic regression and Poisson hurdle models were calculated. MIH was diagnosed in 13.6% of the study population. Approximately 16.4% of the children demonstrated caries-related defects (D3-4MFS > 0). The mean season-adjusted concentration of 25(OH)D was 75.8 nmol/l (standard deviation 22.0 nmol/l).

After adjusting for sex, age, body mass index, parental education, equivalent income, and television/personal computer (TV/PC) viewing hours, a 10 nmol/l increase in serum 25(OH)D concentrations was significantly associated with a lower odds ratio of having MIH ( OR = 0.89 ; P = 0.006). Furthermore, higher 25(OH)D values were associated with a lower number of caries-affected permanent teeth. It is concluded that elevated serum 25(OH)D concentrations were associated with better dental health parameters.

PMID: 25503610

Map of MH problems around the world

Notice: Except for Brazil (40%!), the problems are not near the equator

See also VitaminDWiki

• Tooth loss reduction by 15 percent associated with 10 ng higher vitamin D – May 2014

• Dental health improved with more than 800 IU of vitamin D – June 2013

• UVB added in classroom reduced cavities, increased height, increased academics. etc

  Review of Dental Caries at Vitamin D Council (Sept 2014) includes the following

• Taking vitamin D supplements resulted in a 47% reduced rate of dental caries.

• Taking vitamin D supplements had no effect on caries in those older than 13 years old, especially in girls.

• Dental caries are more common in late winter and early spring, which is when vitamin D levels tend to be lower.

• Children with severe ECC have lower vitamin D levels compared to children without caries.

• Mothers with low vitamin D levels are more likely to give birth to children who develop dental caries.

• Vitamin D supplementation may help reduce the risk of developing dental caries.