Severe depression while pregnant reduces Vitamin D by 62 %, resulting in many problems in infant
Serum Vitamin D status in full term neonates with severe perinatal depression
J Neonatal Perinatal Med. 2023 Jun 13. doi: 10.3233/NPM-230020 PDF behind paywall
P Batra 1, P Singh 1, R S Ahmed 2, D Harit 1
Background: Severe perinatal depression is a significant cause of mortality and morbidity in neonates. Vitamin D levels were observed to be low in mothers and their neonates with hypoxic ischemic encephalopathy in some studies, owing to its neuroprotective properties.
Objective: Primary objective was to compare vitamin D deficiency state in full term neonates with severe perinatal depression and healthy term controls. Secondary objectives were to determine sensitivity and specificity of serum 25(OH)D<12 ng/mL in predicting mortality, development of hypoxic ischemic encephalopathy, abnormal neurological examination at discharge, and developmental outcome at 12 weeks of age.
Material and methods: Serum 25(OH)D levels in full term neonates with severe perinatal depression and healthy controls were compared.
Results: Serum 25(OH)D levels in severe perinatal depression and controls (n = 55 each group) were significantly different (7.50 ± 3.53 ng/mL vs 20.23 ± 12.70 ng/mL).
At cut-off of < 12 ng/mL, serum 25(OH)D could predict
mortality with 100% sensitivity and 17% specificity and
poor developmental outcomes with sensitivity of 100% and specificity of 50%
Conclusion: Vitamin D deficiency status at birth can serve as an effective screening tool and poor prognostic markers in term neonates with severe
VitaminDWiki - studies in both categories Depression and Pregnancy
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Intervention studies: Depression reduced by Vitamin D
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VitaminDWiki – Depression contains
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Meta-analyses of Depression and Vitamin D, Omega-3, etc.
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VitaminDWiki - Pregnancy category contains
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VitaminDWiki - Healthy pregnancies need lots of vitamin D contains
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