Seniors raised Vitamin D levels, more COVID survivors, less CKD (Slovakia)

Vitamin D Deficiency Prevalence in Hospitalized Patients with COVID-19 Significantly Decreased during the Pandemic in Slovakia from 2020 to 2022 Which Was Associated with Decreasing Mortality
Nutrients 2023, 15, 1132. https://doi.org/10.3390/nu15051132
Juraj Smaha 1, smaha1@uniba.sk, Peter Jackuliak 1, Martin Kuzma 1, Filip Max 2, Neil Binkley 3 and Juraj Payer 1
5th Department of Internal Medicine, Comenius University Faculty of Medicine, University Hospital, Ruzinovska 6, 826 06 Bratislava, Slovakia
Department of Pharmacology and Toxicology, Comenius University Faculty of Pharmacy, Odbojarov 10, 832 32 Bratislava, Slovakia
Department of Medicine, Geriatrics Faculty, Medical Sciences Center, University of Wisconsin, 1300 University Ave, Madison, WI 53706-1510, USA

Curve of Vitamin D vs survive COVID - data from both winters

Independent variables: b1 = age, b2 = sex, b3 = Vit D level
Dots on the curve appear to have no relationship to the data
The coronavirus disease 2019 (COVID-19) pandemic has led to changes in lifestyle, which could influence vitamin D status on a population level. The purpose of our study was to compare 25-hydroxyvitamin D (25[OH]D) levels in patients hospitalized because of severe COVID-19 during two waves of the pandemic (2020/21 vs. 2021/22). A total of 101 patients from the 2021/22 wave were compared with 101 sex- and age-matched subjects from the 2020/21 wave. Patients from both groups were hospitalized during the winter season from 1 December to 28 February. Men and women were analyzed together and separately. The mean 25(OH)D concentration increased from 17.8 ± 9.7 ng/mL to 25.2 ± 12.6 ng/mL between waves. The prevalence of vitamin D deficiency (<20 ng/mL) decreased from 82% to 54%. The prevalence of adequate serum 25(OH)D concentration (>30 ng/mL) increased from 10% to 34% (p < 0.0001). The proportion of patients with a history of vitamin D supplementation increased from 18% to 44% (p < 0.0001). Low serum 25(OH)D concentration was independently associated with mortality after adjusting for age and sex for the whole cohort of patients (p < 0.0001). The prevalence of inadequate vitamin D status in hospitalized patients with COVID-19 in Slovakia decreased significantly, probably due to a higher rate of vitamin D supplementation during the COVID-19 pandemic.
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