Risk of Cesarean 2X higher if low vitamin D
Maternal Vitamin D Status and Delivery by Cesarean
Nutrients 2012, 4(4), 319-330; doi:10.3390/nu4040319
Theresa O. Scholl 1 scholl@umdnj.edu , Xinhua Chen 1 and Peter Stein 2
1 Two Medical Center Drive, Department of Obstetrics and Gynecology, SOM, University of Medicine and Dentistry of New Jersey, Stratford, NJ 08084, USA
2 Two Medical Center Drive, Department of Surgery, SOM, University of Medicine and Dentistry of New Jersey, Stratford, NJ 08084, USA
Received: 29 November 2011; in revised form: 23 February 2012 / Accepted: 13 April 2012 / Published: 20 April 2012
Abstract: We examined the association of vitamin D deficiency to risk of cesarean delivery using prospective data in a cohort of 1153 low income and minority gravidae. Circulating maternal 25-hydroxyvitamin D and intact parathyroid hormone were measured at entry to care 13.73 ± 5.6 weeks (mean ± SD). Intake of vitamin D and calcium was assessed at three time points during pregnancy. Using recent Institute of Medicine guidelines, 10.8% of the gravidae were at risk of vitamin D deficiency, and 23.8% at risk of insufficiency. Maternal 25-hydroxyvitamin D was related positively to vitamin D and calcium intakes and negatively to circulating concentrations of parathyroid hormone. Risk for cesarean delivery was increased significantly for vitamin D deficient women; there was no increased risk for gravidae at risk of insufficiency.
When specific indications were examined, vitamin D deficiency was linked to a 2-fold increased risk of cesarean for prolonged labor .
Results were the similar when prior guidelines for vitamin D deficiency (25(OH)D < 37.5nmol/L) and insufficiency (37.5–80 nmol/L) were utilized.
(AOR = Adjusted Odds Ratio)
PDF is attached at the bottom of this page
Summary of RCT without enough participants:
400 IU ==> 25% Cesarean; 4000 IU ==> 14% Cesarean
See also VitaminDWiki
C-section 4X more likely when vitamin D less than 37 ng – many items
Overview Pregnancy and vitamin D has the following summary
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