Overview Autism and vitamin D

Created July 2010
* Autism has seen huge increases around the world in the past few decades * There are many proposed reasons for the increase; including antibiotics, Roundup, genetics, vaccines, viral infections, heavy metals, * There are 27+ reasons to associate Autism with low vitamin D * Children of women who had higher levels of vitamin D have a lower risk of autism *            (More Autism info below) {include}

  • FACT: Studies have shown many associations between autism to low Vitamin D

  • FACT: Clinical trial has prevented Autism with Vitamin D during pregnancy

  • FACT: Clinical trial has treated autism in children

  • RECOMMENDATION: Take extra vitamin D when pregnant

    • There is a tiny risk in taking vitamin D during pregnancy, but a major risk in not doing so if you already have an autistic child

VitaminDWiki - Autism category contains

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Summary of this page by CHAT-GPT-4 Sept 2023

Facts:

  • Many studies have shown associations between autism and low Vitamin D levels.

  • Clinical trials have shown that Vitamin D during pregnancy can prevent Autism.

  • Clinical trials have also treated autism in children with Vitamin D.

  • The recommendation is to take extra vitamin D when pregnant. While there's a small risk in taking vitamin D during pregnancy, the risk of not doing so is significant, especially if you already have an autistic child.

    Highlighted Studies and Information:

  • Autism was 20X more likely if acetaminophen (Tylenol) was used from age 12 - 18 months (July 2023).

  • There were over 200 studies suggesting a link between vaccines and autism as of 2023.

  • The US saw an explosion of autism cases, with the cost associated with autism reaching $223 billion/year in 2020.

  • Almost 7% of 8-year-old boys in California had autism in 2020, with males being 3.8X more likely to have autism than females.

  • Autism symptoms, in some cases, disappeared by changing the diet.

  • A 3X increase in autism in boys by age 3 was observed if they had 3 hours of daily screen time before age 1 (potentially due to less vitamin D exposure) as of Feb 2022.

  • Autism may be synergistically treated by Vitamin D and probiotics (July 2022).

  • Autism was 2X to 3X more likely if there was a poor Vitamin D Receptor (June 2020).

  • Vaccinations resulted in increased office visits for children 16 months later (Nov 2020).

  • Dr. Cannell, who is associated with the Vitamin D Council, has written and spoken extensively about the relationship between autism and Vitamin D. He suggests that autism can be treated with Vitamin D levels between 80 – 120 ng.

Report on Autism and Vitamin D by Perplexity AI June 2025

📄 Download the PDF from VitaminDWiki

Could You be a "Little Bit Autistic?": The Nonvisible Part of the Spectrum - May 2024

6 minute video by the author

The Nonvisible Part of the Autism Spectrum : Could You be a "Little Bit Autistic?" (Optimistic Autism Book 1) Amazon $10

includes a substantial free portion of his book

Autism decreased by Omega-3, increased by Omega-6

Autism treated by a combination of Vitamin D plus Omega-3 - case report 2020

Omega-3 PUFAs and vitamin D co-supplementation as a safe-effective therapeutic approach for core symptoms of autism spectrum disorder: case report and literature review

Nutritional Neuroscience. An International J. on Nutrition, Diet and Nervous System. Vol 23, 2020 - Issue 10 https://doi.org/10.1080/1028415X.2018.1557385

Marco Infante,Barry Sears,Angela Maria Rizzo,Daniela Mariani Cerati,Massimiliano Caprio,Camillo Ricordi

Introduction: Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized by abnormal development of cognitive, social, and communicative skills. Although ASD aetiology and pathophysiology are still unclear, various nutritional factors have been investigated as potential risk factors for ASD development, including omega-3 polyunsaturated fatty acids (PUFAs) and vitamin D deficiency. In fact, both omega-3 PUFAs and vitamin D are important for brain development and function.

Case report: Herein, we report the case of a 23-year-old young adult male with autism who was referred to our Unit due to a 12-month history of cyclic episodes of restlessness, agitation, irritability, and oppositional and self-injurious behaviors. Laboratory tests documented a markedly altered omega-6/omega-3 balance, along with a vitamin D deficiency, as assessed by serum levels of 25-hydroxyvitamin D. Omega-3 and vitamin D co-supplementation was therefore started, with remarkable improvements in ASD symptoms throughout a 24-month follow-up period. A brief review of the literature for interventional studies evaluating the efficacy of omega-3 or vitamin D supplementation for the treatment of ASD-related symptoms is also provided.

Conclusion: To our knowledge, this is the first case reporting remarkable beneficial effects on ASD symptoms deriving from omega-3 and vitamin D combination therapy. This case report suggests omega-3 and vitamin D co-supplementation as a potential safe-effective therapeutic strategy to treat core symptoms of ASD. However, larger studies are needed to evaluate the real efficacy of such therapeutic approach in a broader sample of ASD patients.

📄 Download the PDF from VitaminDWiki

VitaminDWiki - studies in both categories Autism and Omega-3

This list is automatically updated

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Autism appears to be somewhat treated by Omega-3; I wonder if it might prevent it as well - March 2017
Omega-3 polyunsaturated fatty acids and/or vitamin D in autism spectrum disorders: a systematic review - Aug 2023

https://doi.org/10.3389/fpsyt.2023.1238973 FREE PDF

Autism may be associated with Increased Omega-6 (which blocks Omega-3) Aug 2024

mercola

Autism Risk factors

Having an autistic sibling: 20X

2014

Proven to be greatly decreased if the mother took lots of vitamin D in subsequent pregnancy

Autism 20X more likely if acetaminophen (Tylenol) from age 12 - 18 months - July 2023
Many childhood vaccinations: 4.4 X
Father over age 50: 2.2 X
  • A review of the risk factors for Autism - Oct 2024 - [https://doi.org/10.1093/eurpub/ckae144.1324FREE PDF]
Mother lived near a freeway during the third trimester of pregnancy: 2X

https://www.niehs.nih.gov/health/topics/conditions/autism

Less than 6 months between births 2.5X

Kaiser Probably Low vitamin D

200+ studies: Vaccines ==> Autism - 2023

If vaccines don't cause autism, then how do you explain all this evidence? Substack June 2023]

  • "There are large cohorts with a no vaccination policy which have NO autism."

  • Clinical pediatric practice for 35 years gave no vaccines and had ZERO autistic children.

    Two of his charts: many more health problems in vaccinated

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See also in VitaminDWiki: Problems after childhood vaccinations - many studies

5 vaccine ==> autism studies - Sept 2024

International scientists have found autism's cause. What will Americans do? Substack Handley

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"CDC AND NIH UNABLE TO PROVIDE A SINGLE STUDY TO SUPPORT THE SAFETY OF INJECTING ALUMINUM ADJUVANTS DESPITE ITS WIDESPREAD USE IN CHILDHOOD VACCINES"

US Explosion of Autism

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The chart is adapted from http://autisminnb.blogspot.com/2011/01/autism-speaks-cdc-autism-prevalence.html

Autism cases in U.S. jump to 1 in 45 Nov 2015 - based on 2014 data

In 2014, it was 75 % boys, 25 % girls.

Autism – 1 in 40 children in the US (as of 2016) – Nov 2018

CDC update: 1 in 88 as of 2008 Reported March 2012

This is a 78 % increase in (2003-2008) for ALL children

110% increase for Hispanics and 91% increase for black children (2003-2008) (dark skin strongly points to vitamin D)

CDC PDF of the 2008 study which was finally published in 2012 is attached to the bottom of this page

Prevalence of Autism Spectrum Disorder Among US Children and Adolescents, 2014-2016 JAMA 2018

Leveling out? 1.46% (1 in 68) based on a survey of parents - has the child been diagnosed with Autism

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1 child in 68 CDC March 2014

An increase of about 30% from 2008 to 2010, which is also a 120% increase in the decade since 2000/2002

Autism Tsunami - US cost $223 billion/year in 2020

Autism Tsunami: the Impact of Rising Prevalence on the Societal Cost of Autism in the United States - May 2021

Journal of Autism and Developmental Disorders May 2021 https://doi.org/10.1007/s10803-021-05120-7

Mark Blaxill • Toby Rogers • Cynthia Nevison

The cost of ASD in the U.S. is estimated using a forecast model that, for the first time, accounts for the true historical increase in ASD. Model inputs include ASD prevalence, census population projections, six cost categories, ten age brackets, inflation projections, and three future prevalence scenarios.

Future ASD costs increase dramatically: total base-case costs of

  • $223 (175-271) billion/year are estimated in 2020;

  • $589 billion/year in 2030,

  • $1.36 trillion/year in 2040, and

  • $5.54 (4.29-6.78) trillion/year by 2060,

    with substantial potential savings through ASD prevention . Rising prevalence, the shift from child to adult-dominated costs, the transfer of costs from parents onto the government, and the soaring total costs raise pressing policy questions and demand an urgent focus on prevention strategies.

A modern day witch trial substack by Rogers in May 2023

  • "The titans of the autism industry have officially banned any discussion of the prevalence, causes, and costs of autism in order to continue profiting from the mass poisoning of children."

  • "A societal cost of autism model (or really any cost of disease model) is pretty straightforward. One just has to calculate the prevalence of the condition in the population and then estimate the costs across several categories — lost parental wages, lost personal wages (for the person with the condition), educational costs, healthcare costs, supportive services (particularly housing) costs — and then just multiply the number of people afflicted times the average cost per person to come up with a number for the whole society."

Almost 7% of 8-year-old California boys (1 in 15) had Autism in 2020 (males 3.8X that of females)

Newly released autism prevalence estimates show that the iatrogenocide is expanding - Rogers Substack March 2023

Autism: mitochondria, toxins, probably helped by supplements - Mercola Dec 2021

  • "More recent investigations looking at mitochondrial biomarkers and electron transport chain activity suggest mitochondrial abnormalities may be involved in as many as 80% of cases."

    📄 Download the PDF from VitaminDWiki

Autism and Dr. Cannell (who is Autistic) at the Vitamin D Council (closed ~2018)

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  • Animal study finds that suggests vitamin D may help prevent and treat autistic symptoms. Vitamin D Council Feb 2016

    • ". . . "if you want your children to be free of autism, we recommend both mom and dad supplement with 5,000 IU/day of vitamin D for at least 3 months before conception (this dose will also improve both male and female fertility). Then, the pregnant woman should remain on 5,000 IU/day, and perhaps 10,000 IU/day, which is the No Observed Adverse Effects Level (NOAEL) level for vitamin D intake throughout her pregnancy."
    • "After the child is born, he or she should supplement with at least 1,000 IU/25 pounds of body weight per day. When the child reaches 125 pounds, he or she should take 5,000 IU/day. If the child shows any signs or symptoms of autism, the dose should be increased to 2,000 IU/per day/per 25 pounds of body weight."

    Vitamin D Council Autism Infographic April 2016

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150+ VitaminDWiki pages have AUTISM OR AUTISTIC in the title

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Autism and Vitamin D from Google Scholar 20,900 items Dec 2024

  • Associations Between Vitamin D and Core Symptoms in ASD: An Umbrella Review - Jul 2024 FREE PDF

  • Effects of Vitamin D Supplementation on Children with Autism Spectrum Disorder: A Systematic Review and Meta-analysis - May 2023 doi: 10.9758/cpn.2023.21.2.240 FREE PDF

  • Vitamin D Status in Children with Autism Spectrum Disorders: Determinants and Effects of the Response to Probiotic Supplementation - July 2022 FREE PDF

  • Steroid hormone pathways, vitamin D and autism: a systematic review - Feb 2023 FREE PDF

  • Research Progress on the Role of Vitamin D in Autism Spectrum Disorder - May 2022 FREE PDF

  • Vitamin D receptor gene variants and serum vitamin D in childhood autism spectrum disorder - Aug 2022 FREE PDF

  • Vitamin D: Before, during and After Pregnancy: Effect on Neonates and Children - May 2022 - FREE PDF

    • "...while in infants, the clinical conditions are low birth weight, lower bone mass and possible relationship with the development of such diseases as bronchiolitis, asthma, type 1 diabetes, multiple sclerosis, and autism included as VD non-classical actions."

  • The effect of vitamin D supplementation in the treatment of children with autism spectrum disorder: a systematic review and meta-analysis of randomized controlled trials - Sept 2020 FREE PDF

  • The Role of Vitamin D Supplementation in Children with Autism Spectrum Disorder: A Narrative Review - Dec 2021 FREE PDF

  • Maternal Vitamin D Levels During Pregnancy and Offspring Autism Spectrum Disorder - Dec 2021 - https://doi.org/10.1016/j.biopsych.2021.07.012 1.4X increased risk if < 30 nmol

  • The Relationship between Vitamin D and Autism Spectrum Disorder - Dec 2021   FREE PDF

Autism and Vitamin D on the web

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Is it Time to Give Up on a Single Diagnostic Label for Autism? Scientific American May 2018

  • "That was the ruling by the editors of the authoritative Diagnostic and Statistical Manual in 2013, but it remains controversial" +"All autistic individuals share core features, including social and communication difficulties, unusually narrow interests, a strong need for repetition and, often, sensory issues. Yet these core features vary enormously in how they are manifested and in how disabling they are." +"There are huge disparities in many areas, such as language development or IQ, and in the presence or absence of co-occurring medical conditions and disabilities"

HYPOTHESIS Vaccine ==> increased Autism

The Clear Legal Basis that Vaccines Cause Autism Green Med Info Sept 2018

Lengthy abstract of book How to End the Autism Epidemic Amazon published Sept 2018,

  1. 1 Best Seller in Pediatrics Sept 19, 2018

  • The Vaccine Act has a 3-year statute of limitation, and virtually all Autistic behavior is not detected until after the 3-year limitation

  • The one case in which Autism did start within the 3-year time limit was conceded by the govt (and the evidence was sealed), but the 5,500 other Autism claims were thrown out

    Table Of Contents

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Clinical Review of Autism and Vitamin D 2012 - excellent

[dl2624] if registered (free) for VitaminDWiki

Roundup and Autism

Powerful chart of the increase in Autism and increase in GMO food

from http://www.examiner.com/article/data-show-correlations-between-increase-neurological-diseases-and-gmos

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Roundup May Be Most Important Factor in Development of Autism . . Mercola June 2013

Dr. Seneff publications many on interactions of roundup on Autism

Seneff Nov 2014 Winston Price Conference

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See also VitaminDWiki

Which has many charts of increases in diseases with Glyphosate - which are HIGHLY LIKELY

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Perhaps many Females are autistic - but they have very different symptoms than males.

  • Why It’s So Difficult to Diagnose Autism in Girls Slate Oct 2015
    • "Some researchers theorize that girls are better than boys at camouflaging their symptoms, particularly during highly structured interactions such as clinic visits. For instance, a colleague of mine described girls with autism as “caricatures” in social interactions. These girls may be motivated to interact, but their behaviors seem exaggerated."
  • The Invisible Women With Autism Atlantic Mag Oct 2015
    • Similar article to Slate - very interesting
    • Wonder if the perceived ratio of male/female will decrease in the future
  • Vitamin D and Autism Spectrum Disorder: A Literature Review - 2016, 35 pages

Half of Autistic children have sleep problems such as insomnia

Autism and Sleep - What Parents Need to Know - Nov 2019

  • 65% have shorter REM sleep, and many autistic children have sleep apnea

  • Bright light in the morning seems to help - similar to helping people with Seaonal Affective Disorder

    It appears that Autistics supplemented with Vitamin D sleep better

    Items in both categories, Autism and Sleep, are listed here:

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Many autism symptoms disappear by changing the food

sulforaphane

Fever Benefits for Autism in a Food Video and Transcript -Dr. Greger March 2021

Nobel Prize for Medicine for brain ailments went to the “father of fever therapy,”

When the brain gets too hot, it generates heat shock proteins to protect itself

sulforaphane, the active ingredient in cruciferous vegetables such as broccoli, kale, and collard greens, activates the heat shock response.

His 2nd video on Autism and Food points out that four different aspects of Autism are treated by sulforaphane

"During the 18-week study, between 35 and 60 percent of those taking sulforaphane showed decreases in characteristic autism symptoms like repetitive movements, irritability, hyperactivity, and communication problems. "

A Randomized Controlled Dietary Trial for Autism June 2021, Dr. Greger

All had symptoms reduced after a gluten- and casein-free diet for a year

3X increase in Autism in boys by age 3 if 3 hours of daily screen time before age 1 (less vitamin D) - Feb 2022

Screen time in first year may raise autism risk at age 3 MDEdge   FREE PDF

16p11.2 deletion syndrome: gene defect associated with Multiple Sclerosis and low vitamin D - June 2022

Pesticides may increase the risk of Autism - Oct 2021

Autism Spectrum Disorder and Prenatal or Early Life Exposure to Pesticides: A Short Review - Oct 2021 https://doi.org/10.3390/ijerph182010991 FREE PDF

  • "Conclusions: Among the different environmental pollutants, pesticides should be considered as emerging risk factors for ASD."

See also: Pesticides 8 X less likely to result in female infertility if take vitamin D – Sept 2023

VitaminDWiki - Does a vaccine increase the risk of Autism – March 2019

See also: Vaccinations resulted in increased office visits for children 16 months later - Nov 2020

  Autism not mentioned, but huge increases in Asthma, ADHD, and 13 othe health issues

7+ Virus pages have AUTISM OR AUTISTIC in the title

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Autism is associated with other categories: Pregnancy 30, Infant-Child 19, ADHD 15, Intervention 11, Cognitive 10, Omega-3 7, Virus 6, Depression 6, Vitamin D Receptor 5, etc.

Books, videos on Vitamin D 4, Antibiotics, probiotics 4, Skin - Dark 4 ,Youth 4, Sleep 4; as of May 2024

Close Associations

Short url = http://is.gd/DAutism

Tags: Autism Greger Overview Treatment