Nerve growth and survival depends on BDNF (Brain-Derived Neurotrophic Factor), which is associated with Vitamin D

In VitaminDWiki

• Beneficial action of resveratrol: How and why (BNDF, etc.)– Feb 2016 in VitaminDWiki

• Stressors as a fetus or child can cause health problems in adult (perhaps via epigenetics) – Dec 2017

• More depression associated with more dementia in seniors (vitamin D not mentioned) – July 2014

• Omega-3, Vitamin D, and other nutrients decrease mental health problems – March 2015

VitaminDWiki is accumulating references

• Why BDNF Is Miracle-Gro For Your Brain July 2017

• 54 Ways To Increase BDNF (Brain-Derived Neurotrophic Factor) March 2017

• Quercetin attenuates cell apoptosis in focal cerebral ischemia rat brain via activation of BDNF-TrkB-PI3K/Akt signaling pathway Dec 2012

  • Note: Quercetin improves the Vitamin D Receptor
• Resveratrol Increases Serum BDNF Concentrations and Reduces Vascular Smooth Muscle Cells Contractility via a NOS-3-Independent Mechanism Feb 2017
  • Free PDF online Note: Resveratrol improves the Vitamin D Receptor
• Dietary zinc supplementation of 3xTg-AD mice increases BDNF levels and prevents cognitive deficits as well as mitochondrial dysfunction Oct 2010
  • Free PDF online. Note: Zinc increases Vitamin D levels
• Effects of vitamin D supplementation on neuroplasticity in older adults: a double-blinded, placebo-controlled randomised trial Jan 2015
  • 2,000 IU vitamin D daily got average vitamin D level to only 32 ng and did not have help brain much

• BNDF Wikipedia

  • “. . helping to support the survival of existing neurons, and encourage the growth and differentiation of new neurons and synapses.”
  • “It is also expressed in the retina, motor neurons, the kidneys, saliva, and the prostate.”
  • “BDNF itself is important for long-term memory.”
  • “Various studies have shown possible links between BDNF and conditions, such as depression,^[63][64] schizophrenia,^[65] obsessive-compulsive disorder,^[66] Alzheimer's disease,^[67] Huntington's disease,^[68] Rett syndrome,^[69] and dementia,^[70] as well as anorexia nervosa^[71] and bulimia nervosa.^[72]
    • Note: Most of these conditions are strongly also associated with low vitamin D

• Serum BDNF Concentrations Show Strong Seasonal Variation and Correlations with the Amount of Ambient Sunlight PLOS ONE - 2012

  • has the following chart, 📄 Download the PDF from VitaminDWiki
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• BDNF brain derived neurotrophic factor NCBI Gene
  • “Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients.”
  • BDNF is expressed in more than just the brain
  •