Multiple Sclerosis and small doses of Vitamin D – meta-review
They consider >1,000 IU to be “high dose”
For MS high dose should be 20X higher
More than one nutrient is used by Dr. Coimbra
Dose size varies with the patient (not one size fits all)
No randomized controlled trials for Dr. Coimbra – all patients are treated, not just half
They thus gnore the success at CURING > 1,000 MS patients by Dr. Coimbra with Vitamin D, etc.
- The words Coimbra or Brazil do not occur even once in the meta-review
See VitaminDWiki
Multiple Sclerosis and (lots of) Vitamin D - book by patient on Coimbra protocol - Feb 2016
Vitamin D for the Treatment or Prevention of Multiple Sclerosis: A Review of the Clinical Effectiveness
Published on: March 10, 2016 Project Number: RC0755-000
Product Line: Rapid Response
📄 Download the PDF from VitaminDWiki
Question
What is the clinical effectiveness of vitamin D supplementation for the prevention of multiple sclerosis?
What is the clinical effectiveness of high versus low dose vitamin D supplementation for the prevention of multiple sclerosis?
What is the clinical effectiveness of vitamin D supplementation for the treatment of multiple sclerosis?
What is the clinical effectiveness of high versus low dose vitamin D supplementation for the treatment of multiple sclerosis?
Key Message
Four systematic reviews,
eight randomized controlled trials, and
three non-randomized studies
were identified regarding the clinical effectiveness of vitamin D supplementation for the prevention or treatment of multiple sclerosis. Due to substantial heterogeneity between studies, the evidence for most clinical outcomes was limited and often conflicting. Very limited evidence suggests a potential benefit of vitamin D supplementation for the prevention of MS, but this needs to be verified by future studies. Results of treatment of MS with vitamin D were inconsistent, with most evidence suggesting no effect on disability scores, and relapse rates. There were both positive and negative results for immunologic factors, imaging studies, and functional outcomes. Safety data suggests that high dose vitamin D is well tolerated and associated with minimal risk.